A5102744444- Esophageal Cancer Research and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Osteoarthritis Treatment and Mechanisms
- Remote Sensing in Agriculture
- Cancer-related molecular mechanisms research
- Metastasis and carcinoma case studies
- Bone Metabolism and Diseases
- Head and Neck Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Circular RNAs in diseases
- Tracheal and airway disorders
- Cancer Diagnosis and Treatment
- Remote Sensing and LiDAR Applications
- Colorectal Cancer Treatments and Studies
- HER2/EGFR in Cancer Research
- Actinomycetales infections and treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Pancreatitis Pathology and Treatment
- Wnt/β-catenin signaling in development and cancer
- Cancer Immunotherapy and Biomarkers
- Biometric Identification and Security
- Advanced Steganography and Watermarking Techniques
People's Liberation Army 401 Hospital
2025
Fudan University Shanghai Cancer Center
2013-2024
Wuhan University
2009-2024
Huazhong Agricultural University
2024
Fudan University
2008-2023
Tongren Hospital
2023
Shanghai Jiao Tong University
2023
Jilin Province Tumor Hospital
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2014-2023
Shanghai Medical College of Fudan University
2014-2023
Abstract Background Chylothorax is a rare but serious postoperative complication in esophageal cancer patients. The aim of this study was to identify risk factors associated with chylothorax and the indication for surgical intervention. Methods A consecutive series 1290 patients who underwent esophagectomy included. Peri‐operative data, including morbidity mortality, were analyzed. Results Thirty‐four (2.6%) developed had significantly higher instances pneumonia (26.5% vs. 11.1%, P = 0.012)...
Sweet esophagectomy is performed widely in China, while the Ivor-Lewis procedure, with potential benefit of an extended lymphadenectomy, limitedly conducted owing to concern for a higher risk morbidity. Thus, role procedure thoracic esophageal cancer needs further investigation.To determine whether associated increased postoperative complications compared procedure.A randomized clinical trial was from May 2010 July 2012 at Fudan University Shanghai Cancer Center, Shanghai, 300 patients...
To investigate whether survival is improved by using the right thoracic approach (extended lymphadenectomy) compared with left (limited for esophageal cancer.The optimal surgical technique cancer remains unclear.Between May 2010 and July 2012, 300 patients middle lower carcinoma were randomized to receive esophagectomy through either or approach. Of these, 286 squamous cell determined postoperative pathology included in this analysis. Disease-free (DFS) overall (OS) between (n = 146) groups...
CD44, a transmembrane glycoprotein expressed in variety of cells and tissues, has been implicated tumour metastasis. But the molecular mechanisms CD44-mediated cell metastasis remain to be elucidated. The downregulation CD44 was determined by immunofluorescence. Moreover, motility breast cancer detected wound-healing transwell experiments. Then spontaneous CD44-silenced MDA-MB-231 tested histology with BALB/c nude mice. A positive correlation between Na+/H+ exchanger isoform 1 (NHE1) found...
Abstract Background The benefit and harm of three-field lymphadenectomy for oesophageal cancer are still unknown. aim this study was to compare overall survival morbidity mortality between three- two-field in patients with squamous cell carcinoma. Methods Between March 2013 November 2016, carcinoma the middle or distal oesophagus were assigned randomly open oesophagectomy (cervical–thoracic–abdominal) (thoracic–abdominal) lymphadenectomy. No chemo(radio) therapy given before surgery. This...
The study aims to evaluate the safety and availability of totally minimally invasive Ivor-Lewis esophagectomy (MIIE) with single-utility incision video-assisted thoracoscopic surgery. Forty-one patients mid-lower thoracic esophageal cancer were prospectively treated MIIE. Two stages laparoscopic-thoracoscopic procedures performed. first 29 four-port surgery (Group 1); others 2). Short-term clinicopathological outcomes examined. All had negative tumor margins pathologically staged from T1N0M0...
Osteoarthritis (OA) is a common degenerative disease characterized by degeneration of articular cartilage. Increasing studies showed that long noncoding RNAs (lncRNAs) play important roles in the cartilage damage. However, little known about role UCA1 osteoarthritis. The expression level was upregulated OA Overexpression suppressed miR-204-5p chondrocytes. downregulated Moreover, negatively correlated with Elevated promoted chondrocytes cell proliferation and overexpression proliferation. In...
Mounting studies have shown that long noncoding RNAs (lncRNAs) play important roles in the development and occurrence of several human diseases.However, role LINC00461 osteoarthritis (OA) remains obscure.A CCK-8 assay was performed to detect cell viability, qRT-PCR analysis used measure mRNA expression.The targeting by miR-30a-5p 3'UTR detected using a luciferase reporter assay.Our data indicated inflammatory mediators IL-6 TNF-α induced expression chondrocytes upregulated OA...
We compared video-assisted thoracoscopic surgery (VATS) lobectomy and stereotactic body radiation therapy (SABR) to explore clinical outcomes in the treatment of patients with early stage NSCLC.Major medical databases were systematically searched identify studies on VATS SBRT published between January 2010 October 2015. English publications I II NSCLC adequate doses included. A multivariate random effects model was used perform meta-analysis compare overall survival (OS) disease-free (DFS)...
Abstract High-affinity potassium transporters (HKTs) play an important role in plants responding to salt stress, but the transport properties of soybean HKT at molecular level are still unclear. Here, using Xenopus oocyte as a heterologous expression system and two-electrode voltage-clamp technique, we identified four transporters, GmHKT1;1, GmHKT1;2, GmHKT1;3 GmHKT1;4, all which belong type I subfamily, have distinct ion properties. While GmHKT1;2 function Na+ GmHKT1;1 is less selective...
For the surgery of esophageal cancer, cervical, mediastinal, and abdominal lymph node dissection (three-field dissection, 3FLND) is still controversial in most countries. This study aims to provide additional evidence this procedure comparing with mediastinal-abdominal (two-field 2FLND) from a high volume center China, also attempts identify routes reduce postoperative complications associated 3FLND.From January 2009 December 2013, 348 consecutive patients received esophagectomy 3FLND 1,406...
To investigate the impact of prolonged length stay (LoS) on long-term mortality in patients who have undergone curative resection for esophageal cancer (EC).
Digital images are facing trustworthy crisis with the emergence of various digital image process tools and steganography tools. Current forensic methods can not evaluate image's trustworthiness. Base on Dempster-Shafer (D-S) evidence theory, this paper proposed a new model which effectively Instead using Dempster's original rule combination, we use feature fusion method to resolve problem conflict. Experimental results show that only trustworthiness effectively, but also some problems...
Abstract Background To compare the efficacy and safety of postoperative extensive target volume irradiation with elevated radiation dose concurrent chemotherapy radiotherapy only for treatment esophageal squamous cell carcinoma. Methods This trial was a single-arm phase II trial. Patients who underwent radical transthoracic resection negative margins within 3 months histologically confirmed carcinoma (pT3-4N0M0 or pTxN + M0, AJCC 7th) were eligible this study. Postoperative performed at...
For patients diagnosed with locally advanced esophageal cancer, neoadjuvant therapy followed by surgery is the most common approach. However, randomized trials resulted in inconsistent conclusions. We conducted this retrospective study to evaluate influence of on postoperative events and disease-free survival (DFS) overall (OS).We retrospectively reviewed all underwent following for squamous cell carcinoma (ESCC) during January 1st, 2013 December 31st, 2015 Fudan University Shanghai Cancer...