- Phytochemicals and Antioxidant Activities
- Diet and metabolism studies
- Gut microbiota and health
- Bone health and osteoporosis research
- Cardiovascular Health and Disease Prevention
- Bone Metabolism and Diseases
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Antioxidant Activity and Oxidative Stress
- Eating Disorders and Behaviors
- Nutrition, Genetics, and Disease
- Blood Pressure and Hypertension Studies
- Mindfulness and Compassion Interventions
- Coronary Interventions and Diagnostics
- Nutrition and Health in Aging
- Adipokines, Inflammation, and Metabolic Diseases
- Phytoestrogen effects and research
- Cardiac Imaging and Diagnostics
- Heart Rate Variability and Autonomic Control
- Muscle metabolism and nutrition
- Vitamin D Research Studies
- Food composition and properties
- Acute Myocardial Infarction Research
- Bone health and treatments
- Probiotics and Fermented Foods
Colorado State University
2016-2025
Florida State University
2013-2023
Princess Margaret Cancer Centre
2023
Tallahassee Orthopedic Clinic
2015-2019
Nutrition Sciences (Belgium)
2019
Sartorius (United States)
2019
University of Toronto
2005-2012
The Scarborough Hospital
2012
Carolinas Medical Center
2011
Centre for Addiction and Mental Health
2005
This prospective series of results and complications coronary arteriography from the Registry Society for Cardiac Angiography Interventions is largest ever reported. Since initial report published in 1982, artery surgery angioplasty have improved therefore older more symptomatic patients are referred arteriography. More now studied by femoral approach, major techniques similar. Despite studying higher-risk patients, remarkably similar to those reported series. Because sicker being studied,...
Background/Objectives: Microgreens are rich in nutrients and phytochemicals that can support healthy aging, including attenuation of cardiovascular disease risk. The nutrient phytochemical contents red beet (i.e., bull’s blood’ beet, Beta vulgaris) cabbage (Brassica oleracea var capitate) microgreens, as well existing preclinical evidence suggest their cardioprotective effects, but the feasibility, gastrointestinal tolerability, human health effects daily microgreen consumption unknown. This...
Abstract In a 42‐month period, 218 deaths occurred in 222, 553 patients undergoing coronary arteriography (0.098%). Age > 60 years, NYHA Class IV function, presence of left main disease, and ejection fraction < 30% all significantly increased the risk procedure. Sex approach (brachial or femoral) used for catheterization did not affect mortality. Since SCAI report 1982, death rate has dropped high‐risk patients. Low‐risk (NYHA I normal arteries) who died generally were elderly had...
In this study, we quantify the relative damage enhancement due to presence of gold nanoparticles (GNP) in vitro a clinical 6 MV beam for various delivery parameters and depths. It is expected that depths modes produce larger proportions low-energy photons will have effect on cell samples containing GNP. HeLa cells with without 50 nm GNP were irradiated at 1.5, 5, 10, 15 20 cm. Conventional beams square aperture sizes 10 cm isocenter, flattening filter free (FFF) used. Relative DNA was...
Microgreens are an emerging functional food crop with promise for sustainably diversifying global systems, facilitating adaptations to urbanization and climate change, promoting human health. Previous work suggests microgreens have high nutritional quality, low environmental impacts, broad consumer acceptance. For better reception into the system increased per capita consumption, research is needed elucidate acceptance of various species, including factors contributing their or lack thereof....
Probiotics are increasingly used by consumers and practitioners to reduce gastrointestinal (GI) distress improve gut function. Here, we sought determine whether the addition of supplemental bacteriophages (PreforPro) could enhance effects a common probiotic, Bifidobacterium animalis subsp. lactis (B. lactis) on GI health. A total 68 participants were enrolled in 4-week, randomized, parallel-arm, double-blind, placebo-controlled trial where primary outcomes included self-assessments health,...
This randomized, double-blind, placebo-controlled trial showed that blueberries improve endothelial function through reduced oxidative stress in postmenopausal women with above-normal blood pressure.
This study presents the anti-inflammatory and antioxidative properties of dried plum (Prunus domestica L.) polyphenols in macrophage RAW 264.7 cells. We hypothesized that have strong antioxidant against lipopolysaccharide (LPS)-induced production pro-inflammatory markers, nitric oxide (NO) cyclooxygenase-2 (COX-2), lipid peroxidation product, malondialdehyde, activated To test this hypothesis, cells were stimulated with either 1 μg ml(-1) (for measurement NO production) or ng COX-2...
Oxidative stress and inflammation are central to the development of a number chronic diseases including cardiovascular disease previous research suggests that blueberry consumption may attenuate these processes. The present study investigated effects blueberries on blood biomarkers oxidative stress, inflammation, antioxidant defense in postmenopausal women with pre- stage 1-hypertension. In randomized, parallel-arm, double-blind, placebo-controlled clinical trial, 40 1-hypertensive aged 45...
Greater than one-third of adults in the United States have metabolic syndrome (MetS), a cluster risk factors highly associated with development cardiovascular diseases. Premature vascular dysfunction MetS may lead to accelerated age-related atherogenesis and arterial stiffening, thereby increasing risk. Montmorency tart cherries (
Mounting evidence indicates that blueberry consumption is associated with a variety of health benefits. It has been suggested regular blueberries can support and/or protect against cardiovascular disease and function, pre-diabetes type 2 diabetes, brain cognitive function in individuals conditions age-related decline. Further, mechanistic investigations highlight the role anthocyanins mediating these benefits, part through interactions gut microbiota. Also, nutritional interventions have...
Microgreens are the young leafy greens of many vegetables, herbs, grains, and flowers with potential to promote human health sustainably diversify global food system. For successful further integration into system evaluation their impacts, it is critical elucidate optimize nutritional quality. We aimed comprehensively evaluate metabolite mineral contents 6 microgreen species, influence maturity on contents. Plant species evaluated were from Brassicaceae (arugula, broccoli, red cabbage),...
Abstract Cannabidiol (CBD) is a dietary supplement with numerous purported health benefits and an expanding commercial market. Commercially available CBD preparations range from tinctures, oils, powders, to foods beverages. Despite widespread use, information regarding bioavailability of these formulations limited. The purpose this study was test the two oral in humans explore their potential acute anti‐inflammatory activity. We conducted pilot randomized, parallel arm, double‐blind 10...
Recent preclinical data suggest that alterations in the gut microbiota may be an important factor linking obesity to vascular dysfunction, early sign of cardiovascular disease. The purpose this study was begin translation these by examining whether phenotypes humans are transmissible through microbiota. We hypothesized germ-free mice colonized with from obese individuals would display diminished function compared receiving lean individuals.We transplanted fecal material and age-and...
Obesity is a costly and ongoing health complication in the United States globally. Bioactive-rich foods, especially those providing polyphenols, represent an emerging attractive strategy to address this issue. Berry-derived anthocyanins their metabolites are of particular interest for bioactive effects, including weight maintenance protection from metabolic aberrations. Earlier findings small clinical trials suggest modulation substrate oxidation glucose tolerance with mediation prospective...
Menopause leads to an increased risk for osteoporosis in women. Although drug therapies exist, increasing numbers of people prefer alternative such as dietary supplements, example, calcium, vitamin D, and collagen hydrolysates the prevention treatment osteoporosis. We have previously shown that a 3-month intervention using calcium-collagen chelate (CC) supplement was efficacious improving bone mineral density (BMD) blood biomarkers turnover osteopenic postmenopausal This study reports...