Göksel Leblebisatan

ORCID: 0000-0003-3435-757X
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Research Areas
  • Platelet Disorders and Treatments
  • Hemoglobinopathies and Related Disorders
  • Blood groups and transfusion
  • Hemophilia Treatment and Research
  • Iron Metabolism and Disorders
  • Metabolism and Genetic Disorders
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Venous Thromboembolism Diagnosis and Management
  • Genital Health and Disease
  • Blood properties and coagulation
  • Blood disorders and treatments
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Pharmacological Effects and Toxicity Studies
  • Autoimmune and Inflammatory Disorders Research
  • Immune Cell Function and Interaction
  • Neurological and metabolic disorders
  • Parvovirus B19 Infection Studies
  • Hemostasis and retained surgical items
  • Immunodeficiency and Autoimmune Disorders
  • Folate and B Vitamins Research
  • Complement system in diseases
  • Blood Coagulation and Thrombosis Mechanisms
  • Research on Leishmaniasis Studies
  • Muscle and Compartmental Disorders
  • Central Venous Catheters and Hemodialysis

Cukurova University
2015-2024

Adıyaman University
2014

Gaziantep Children's Hospital
2010-2013

Background: Reversible posterior leukoencephalopathy syndrome (PRES) is a neurological disorder characterized by signs of cerebral edema upon radiographic examination. Materials and Methods: We retrospectively analyzed the records nine children with diagnosis PRES. Results: Of patients, seven were receiving immunosuppressive therapy two acute hypertensive crisis associated renal disease. Immunosupressive drugs intrathecal methotrexate in cyclosporine cytarabine one patient, cyclophasphamide...

10.4103/0028-3886.55605 article EN Neurology India 2009-01-01

Background and objective: To determine the prevalence clinical significance of thyroid autoantibodies their influence on treatment response in children with idiopathic thrombocytopenic purpura (ITP). Patient Method: We retrospectively analyzed antithyroglobulin (anti-TG) antithyroid peroxidase (anti-TPO) antibodies from records 151 ITP patients who were admitted to Pediatric Hematology Department Gaziantep University between 2009 2012. Results: Anti-TPO and/or anti-TG was found positive 38...

10.3109/08880018.2012.756564 article EN Pediatric Hematology and Oncology 2013-01-09

Summary. Circumcision is the oldest and most frequent surgical procedure in world especially Turkey as seen other Islamic countries because of religious traditional pressures. In this study, we aim to report experience circumcision at Çukurova University a total 76 patients with haemophilia between 1990 2011. We retrospectively reviewed medical records 69 without inhibitors seven who had been circumcised. Before year 2000, factor concentrates were given before after for 6 – 7 days. After...

10.1111/j.1365-2516.2011.02706.x article EN Haemophilia 2011-12-19

Hemophagocytic lymphohistiocytosis (HLH) is a rare clinical syndrome characterized by uncontrolled activation of cytotoxic T cells and antigen-presenting cells. Common manifestations include high fever, maculopapular rash, neurological symptoms, coagulopathy, abnormal liver function tests [1]. HLH can be either primary, that is, due to an underlying genetic defect, or secondary, associated with malignancies, autoimmune diseases, infections. The true incidence secondary difficult define....

10.3109/08880018.2012.666783 article EN Pediatric Hematology and Oncology 2012-03-30

Ankaferd blood stopper (ABS) is a hemostatic agent used topically for controlling bleedings of skin or mucosal surfaces in Turkey. It currently body injuries, traumas, and minor major surgical interventions. Here we have evaluated 12 pediatric patients with hemorrhagic diathesis on whom was oral bleedings. Topical administered hemorrhages cavity during 15 bleeding attacks. ABS administrations successfully stopped the bleedings, except one patient hemorrhage who did not respond to...

10.1097/mbc.0b013e32834fa837 article EN Blood Coagulation & Fibrinolysis 2012-05-10

Objective: Immune thrombocytopenia (ITP) is a rare autoimmune disease and hematologic disorder characterized by reduced platelet counts that can result in significant symptoms, such as bleeding, bruising, epistaxis, or petechiae.The thrombopoietin receptor agonist eltrombopag (EPAG) second-line agent used to treat chronic ITP purpura adults children. Materials Methods:The present retrospective study evaluated the efficacy, safety, side effects of EPAG treatment pediatric patients with acute...

10.4274/tjh.galenos.2020.2019.0380 article EN Turkish Journal of Hematology 2020-03-17

Cardiac failure due to iron overload remains the most common cause of death in patients with beta-thalassemia major. This study aimed evaluate myocardial function children major using standard echocardiography technique and strain rate imaging.Conventional echocardiographic analysis, tissue velocity imaging, strain/strain imaging left ventricle were evaluated 48 (19 girls, 29 boys; 8.39±4.05 years) 22 healthy (11 11 8±3.72 years).Conventional examinations revealed that had larger ventricular...

10.4274/tjh.2012.0065 article TR Turkish Journal of Hematology 2013-09-05

Glanzman thrombasthenia is a rare hematologic disorder characterized by qualitative thrombocyte abnormality. Patients present with episodic mucocutaneous bleeding. Thrombosis paradox phenomenon observed in patients and generally considered as treatment complication. We 16-year-old girl referred for severe flank pain beginning after of hematuria due to thrombasthenia. The patient underwent endoscopy further diagnosis because the failure radiologic evaluation. Although resolution large clots...

10.1097/mbc.0b013e32834a5c4c article EN Blood Coagulation & Fibrinolysis 2011-10-04

Deficiency of Adenosine Deaminase 2 (DADA2) is a monogenic autoinflammatory disorder characterized by livedo reticularis, skin ulcers, subcutaneous rash, aphthous and leukocytoclastic vasculitis, neurological signs such as early onset stroke polyneuropathy. A minority DADA2 patients suffer from severe cytopenia lymphoproliferation. Herein, we report an adolescent patient, followed up having hematological for many years, eventually diagnosed DADA2. In view the presence elevated acute phase...

10.1080/08880018.2019.1621973 article EN Pediatric Hematology and Oncology 2019-08-18

The literature on the use of recombinant factor VIIa (rFVIIa), which was initially used in hemophiliac patients with inhibitors, for hemorrhages that cannot be managed conventional methods or operations performed safely is increasingly growing. This study presents a group nonhemophiliac hemorrhagic problems hemorrhage risk some interventions were successfully resolved rFVIIa. patient composed 20 different disorders resulting similar results as risk. Most diagnosed liver primary secondary to...

10.1177/1076029608322549 article EN Clinical and Applied Thrombosis/Hemostasis 2008-10-06

There are numerous reports that patients with thalassemia faced hypercoagulability leading to vascular disorders. One of these complications is known as a silent infarct, defined small infarct detected by cerebral imaging but without any neurological symptoms. Since it has progressive nature, vital importance because may lead symptomatic cerebrovascular accidents in the future. Twenty-two children intermedia were enrolled into study and MRI scans performed. All demographic data clinical...

10.1097/mbc.0b013e3283566b0f article EN Blood Coagulation & Fibrinolysis 2012-08-21

Allergic reactions from insect bites are mostly observed with bee stings. Bee sting can be classified into 3 main headings: local, systemic, and rare reactions. Vascular thrombosis is considered both in systemic The wild venom induces the secretion of many inflammatory mediators, including histamine, phospholipase A1, thromboxane, leading to vasoconstriction thrombosis. Inflammatory cytokines also cause endothelial injury deterioration microcirculation. In literature, have been reported...

10.1097/mph.0000000000002072 article EN Journal of Pediatric Hematology/Oncology 2021-01-27

Abstract Transfusion-associated acute lung injury (TRALI) is one of the complications seen due to transfusion. Hypoxemia and bilateral pulmonary infiltration in posteroanterior chest roentgenogram all cases during transfusion or within first 6 hours; fever, hypotension, pink frothy bleeding from endotracheal tube may also be seen. It can following administration any blood product. The management strategies for TRALI include withholding transfusion, positive pressure breathing support,...

10.1055/s-0039-1694991 article EN Journal of Pediatric Intensive Care 2019-08-26
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