A5021019289- Neonatal and fetal brain pathology
- Neonatal Respiratory Health Research
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Infant Development and Preterm Care
- Anesthesia and Neurotoxicity Research
- Stroke Rehabilitation and Recovery
- Advanced MRI Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Venous Thromboembolism Diagnosis and Management
- Neuroscience of respiration and sleep
- Advanced X-ray and CT Imaging
- Medical Imaging Techniques and Applications
- Infectious Encephalopathies and Encephalitis
- Glioma Diagnosis and Treatment
- Congenital Heart Disease Studies
- Genetics and Neurodevelopmental Disorders
- Electrical and Bioimpedance Tomography
- Genomics and Rare Diseases
- Bacterial Infections and Vaccines
- Photoacoustic and Ultrasonic Imaging
- Atomic and Subatomic Physics Research
- Cerebral Venous Sinus Thrombosis
- Cardiovascular Conditions and Treatments
- Advanced Neuroimaging Techniques and Applications
Innsbruck Medical University
2019-2022
Universität Innsbruck
2019-2022
In patients with large ischemic stroke, thrombectomy within 12 hours after onset was superior to best medical treatment in reducing 90-day functional disability irrespective of the collateral status on single-phase CT angiography images.
BACKGROUND: Recent randomized trials demonstrated the beneficial effect of endovascular therapy in patients with low Alberta Stroke Program Early Computed Tomography Score. Despite large follow-up infarct volumes, a significantly increased rate good functional outcomes was observed, challenging role volume as predictive imaging marker. This analysis evaluates extent to which effects thrombectomy on are explained by (1) and (2) early neurological status stroke METHODS: TENSION trial conducted...
Segmentation of specific brain tissue from MRI volumes is great significance for disease diagnosis, progression assessment, and monitoring neurological conditions. Manual segmentation time-consuming, laborious, subjective, which significantly amplifies the need automated processes. Over last decades, active development in field deep learning, especially convolutional neural networks (CNNs), associated performance improvements have increased demand application CNN-based methods to provide...
Cerebellar injury is increasingly recognized as a relevant complication of premature birth. However, the prevalence reduced cerebellar growth and its consequences for neurodevelopmental outcome in preterm infants without overt brain remain to be defined detail. The aim this study was assess transcerebellar diameter (TCD) at term-equivalent age (TEA) very evaluate whether TCD related population.Very underwent magnetic resonance imaging TEA. Infants with any grade supra- or infratentorial were...
Very preterm infants are at risk for adverse neurodevelopmental outcome. To better identify children without brain injury developmental sequelae, we assessed predictive values of supratentorial metrics in relation to outcome.Very underwent magnetic resonance imaging (MRI) term-equivalent age. Infants with any grade supra- or infratentorial according Kidokoro et al. [Pediatrics 2014;134:e444-53] were excluded. Supratentorial (biparietal width, extracerebral space, interhemispheric distance)...
Abstract Objectives We aimed to evaluate the ability of feed-forward neural networks (fNNs) predict neurodevelopmental outcome (NDO) very preterm neonates (VPIs) at 12 months corrected age by using biomarkers cerebral MR proton spectroscopy ( 1 H-MRS) and diffusion tensor imaging (DTI) term-equivalent (TEA). Methods In this prospective study, 300 VPIs born before 32 gestational weeks received an MRI scan TEA between September 2013 December 2017. Due missing or poor-quality data tests, 173...
Abstract Background The epileptic encephalopathies display extensive locus and allelic heterogeneity. Biallelic truncating DOCK7 variants were recently reported in five children with early‐onset epilepsy, intellectual disability, cortical blindness, indicating that deficiency causes a specific type of encephalopathy. Methods We identified 23‐ 27‐year‐old siblings the clinical pattern for deficiency, conducted genome‐wide linkage analysis WES. consequences variant analyzed on transcript...
<b><i>Introduction:</i></b> Prophylactic low-dose paracetamol administration is used to induce closure of the ductus arteriosus. Effects on neurological outcome in preterm infants remain unknown. We compared microstructural brain development very with and without exposure prophylactic by using MR-based diffusion tensor imaging. <b><i>Materials Methods:</i></b> Infants aged &#x3c;32 gestational weeks born between October 2014 December 2018...
Abstract In this article, we described a case of pathogen-induced bilateral optic neuritis accompanying meningococcal meningoencephalitis in an adolescent male. A 15-year-old boy presented to our emergency room due progressive severe headache, stiff neck, diffuse extremity pain, fever, and nausea concerning meningoencephalitis. Intravenous ceftriaxone, metamizole, ondansetron were started immediately. Due acute autonomic dysregulation development petechiae, he was transferred the pediatric...
Zielsetzung We aimed to evaluate if proton magnetic resonance spectroscopy (1H-MRS) and diffusion tensor images (DTI) quantified in very preterm infants (VPIs) at term equivalent age (TEA) enhance the predictive role of conventional MRI for their neurodevelopmental outcome (NDO) corrected 12 months using feed-forward neural-networks (fNNs).