A5022289377- Indoor Air Quality and Microbial Exposure
- Asthma and respiratory diseases
- Air Quality and Health Impacts
- Occupational exposure and asthma
- Allergic Rhinitis and Sensitization
- Pediatric health and respiratory diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Stroke Rehabilitation and Recovery
- Odor and Emission Control Technologies
- Respiratory and Cough-Related Research
- Acute Ischemic Stroke Management
- Noise Effects and Management
- Workplace Health and Well-being
- Climate Change and Health Impacts
- Occupational and environmental lung diseases
- Occupational Health and Safety Research
- Urban Green Space and Health
- Nutritional Studies and Diet
- Toxic Organic Pollutants Impact
- Pesticide Exposure and Toxicity
- Cervical Cancer and HPV Research
- Obesity, Physical Activity, Diet
- Health, Environment, Cognitive Aging
- Carcinogens and Genotoxicity Assessment
- IL-33, ST2, and ILC Pathways
Massey University
2016-2025
University of Otago
2002-2024
Nationwide Children's Hospital
2023
Victoria University of Wellington
2000-2022
Canterbury District Health Board
2022
Monash University
2022
Hawke's Bay Hospital
2022
Auckland University of Technology
2022
Aspirus Wausau Hospital
2022
Capital and Coast District Health Board
2022
The prevalence of allergic airway diseases such as asthma and rhinitis has increased dramatically to epidemic proportions worldwide. Besides air pollution from industry derived emissions motor vehicles, the rising trend can only be explained by gross changes in environments where we live. world economy been transformed over last 25 years with developing countries being at core these changes. Around planet, both developed countries, are undergoing profound Many considered have negative...
<b>Background:</b> The role of the innate immune system in pathogenesis asthma is unclear. Activation receptors response to bacterial lipopolysaccharide, viral infection and particulate matter triggers a pre-programmed inflammatory response, which involves interleukin (IL)8 neutrophil influx. heterogeneous. <b>Aim:</b> To test hypothesis that activation may be relevant mechanism neutrophilic where IL8 levels are increased. <b>Methods:</b> Induced sputum was obtained from non-smoking adults...
Yeast cell wall proteins, including Cwp1p and alpha-agglutinin, could be released by treating the with either beta-1,3-or beta-1,6-glucanases, indicating that both polymers are involved in anchoring proteins. It was shown immunologically beta-1,3- beta-1,6-glucan were linked to yeast alpha-agglutinin. further beta-1,3-glucan protein through a moiety. The moiety removed from other proteins cleaving phosphodiester bridges enzymatically using phosphodiesterases or chemically ice-cold aqueous...
House dust-associated bacterial endotoxins have been shown to be associated with asthma severity, and a similar role has suggested for fungal (1-->3)-beta-D-glucans. In this study the relation between these agents peak expiratory flow (PEF) variability was investigated in 148 children 7 11 yr of age whom 50% had self- or parent-reported chronic respiratory symptoms. All self-monitored twice daily their PEF period 16 wk. Dust samples were collected from mattresses living room bedroom floors,...
The influence of various filter types and extraction conditions on the quantitation airborne endotoxin with Limulus amebocyte lysate test was studied by using dusts sampled in a potato processing plant. Samples were collected an apparatus designed to provide parallel samples. Data from parallel-sampling experiment statistically evaluated analysis variance. In addition, storage detectable concentration investigated commercially available lipopolysaccharides (LPS) endotoxin-containing house...
The aim of the present study was to assess which factors contribute lower prevalence allergic diseases in farmers’ children, and importance timing exposure. In a cross-sectional questionnaire survey, asthma symptoms, hay fever eczema were assessed, as well current, early prenatal farm-related exposures 1,333 children 566 reference aged 5–17 yrs. Farmers’ had incidence symptoms eczema. Current maternal exposure during pregnancy animals and/or grain reduced risk exposure–response association...
The current authors examined whether mite and cat allergen bacterial endotoxin levels in dust of the mothers' mattresses were associated with cord blood immunoglobulin (Ig)E (CB-IgE) newborns. Data from 1,332 term normal weight neonates, an ongoing birth cohort study, influences life-style related factors on immune system development allergies childhood (LISA), complete information exposure to biocontaminants mattress CB-IgE analysed. Two thirds undetectable (<0.35 kU x L(-1)). Thus, 0.35...
ABSTRACT Deletion of GAS1/GGP1/CWH52 results in a lower β-glucan content the cell wall and swollen, more spherical cells (L. Popolo, M. Vai, E. Gatti, S. Porello, P. Bonfante, R. Balestrini, L. Alberghina, J. Bacteriol. 175:1879–1885, 1993; A. F. Ram, C. Brekelmans, W. Oehlen, Klis, FEBS Lett. 358:165–170, 1995). We show here that gas1 Δ release β1,3-glucan into medium. Western analysis medium proteins with β1,3-glucan- β1,6-glucan-specific antibodies showed further at least some released...
Background: Recently, the International Agency for Research on Cancer (IARC) Programme Evaluation of Carcinogenic Risks to Humans has been criticized several its evaluations, and also approach used perform these evaluations. Some critics have claimed that failures IARC Working Groups recognize study weaknesses biases Group members led inappropriate classification a number agents as carcinogenic humans.Objectives: The authors this Commentary are scientists from various disciplines relevant...
BackgroundSeveral small experimental studies and cross-sectional observational have shown that exposure to the natural environment might protect against attention-deficit hyperactivity disorder (ADHD) or moderate symptoms of ADHD in children. We aimed assess whether protects this hypothesised protective effect varies across a child's life course.MethodsWe did longitudinal study with data collected from all children born New Zealand 1998, excluding those without an address history, who were...
Extended-spectrum-beta-lactamase (ESBL)- or AmpC beta-lactamase (ACBL)-producing