A5106406689- Higher Education and Teaching Methods
- Education and Work Dynamics
- Traditional Chinese Medicine Studies
- Monoclonal and Polyclonal Antibodies Research
- Spine and Intervertebral Disc Pathology
- Radiomics and Machine Learning in Medical Imaging
- Venous Thromboembolism Diagnosis and Management
- Pharmacological Effects of Natural Compounds
- HER2/EGFR in Cancer Research
- Intraocular Surgery and Lenses
- Migraine and Headache Studies
- Acute Ischemic Stroke Management
- Animal Nutrition and Physiology
- Smart Agriculture and AI
- Ophthalmology and Visual Impairment Studies
- Invertebrate Immune Response Mechanisms
- Liver Disease Diagnosis and Treatment
- Genetic Syndromes and Imprinting
- Cardiac Imaging and Diagnostics
- Remote-Sensing Image Classification
- Nutritional Studies and Diet
- Retinal and Macular Surgery
- Pathogenesis and Treatment of Hiccups
- Psychosocial Factors Impacting Youth
- Nuclear Receptors and Signaling
China Medical University
2024-2025
Berry Oncology (China)
2025
Center for High Pressure Science & Technology Advanced Research
2025
Air Force Medical University
2015-2025
Sixth Affiliated Hospital of Sun Yat-sen University
2025
Sun Yat-sen University
2025
Jinggangshan University
2025
Erasmus MC
2024
Shangqiu Normal University
2024
Zhongda Hospital Southeast University
2024
<h3>Objective:</h3> To characterize the HER-2/<i>neu</i>oncogene in head and neck squamous cell carcinoma (HNSCC) lines tumor tissue specimens. <h3>Design:</h3> Molecular analysis of amplification expression HNSCC by Southern, Northern, Western blot techniques, HER-2/<i>neu</i>oncoprotein sections immunohistochemical analysis. <h3>Specimens:</h3> Eleven lines, eight paired samples frozen specimens adjacent nonmalignant mucosa, 38 paraffinembedded slides derived from (including those which...
Four experiments were performed to investigate the role of mitogen-activated protein kinase (MAPK) signaling pathway in intestinal absorption phosphorus (P) and calcium (Ca) broiler chickens. Experiment 1 assessed how dietary levels 1,25-dihydroxyvitamin D
Peptidoglycan recognition proteins (PGRPs) are the evolutionarily highly conserved class of pattern receptors, however, their functions on innate immune system and neuro-inflammatory response in aquatic organism still poorly understood. In this study, we systematically investigated molecular PGRPs zebrafish embryos. Firstly, identified three phylogenetic analysis suggested that DrPGRP-5 was a novel member PGRP superfamily evolution. Secondly, endogenous mRNA levels were expressed brain...
Multimorbidity and physical function in older adults have been identified as associated with coronavirus disease 2019 (COVID-19) outcomes. This study aimed to investigate whether multimorbidity affects the association of impaired functional independence (FI) critical COVID-19 among inpatients during peak Omicron infection China. is a multicentre, retrospective cohort northeastern Patients aged ≥ 60 years, who were diagnosed at time admission or hospitalisation. The Barthel index was used...
Accurate preoperative evaluation of rectal cancer lung metastases (RCLM) is critical for implementing precise medicine. While artificial intelligence (AI) methods have been successful in detecting liver and lymph node using magnetic resonance (MR) images, research on still limited. Utilizing MR images to classify RCLM could potentially reduce ionizing radiation exposure the costs associated with chest CT patients without metastases. This study aims develop validate a transformer-based deep...
We determined the association between Life's Essential 8 (LE8) scores and AMD incidence ascertained whether genetic susceptibility modifies it. This prospective cohort study included 268,634 UK Biobank participants with high, moderate, or low cardiovascular health based on LE8 scores. High corresponded to lowest highest disease risks, respectively. The hazard ratios (HRs) 95% confidence intervals (CIs) for were estimated using Cox proportional hazards models. dose-response relationships...
Hepatocellular carcinoma (HCC) is one of the most common cancers. Early detection HCC helps improve patients' 5-year survival rate. Our goal was to identify superior methylation biomarkers develop a methylation-specific quantitative PCR (MS‒qPCR) assay. A five-phase case-control study identified via capture sequencing, TCGA/RNA-seq filtering, technical (MS-qPCR/Sanger) and biological (quadruplex MS-qPCR) validation. Methylated were selected based on differential expression using tissue...
In the context of new education reform, teaching evaluation has been assigned a more important role, especially with introduction and practice “integration evaluation” concept. This paper, in line 2022 Compulsory Education Curriculum Standards’ requirements for classroom evaluation, explores significance “teaching integration” concept its implementation strategies. By reviewing domestic international research, this paper analyzes current research status emerging issues proposes suggestions...
Background Although guidelines on physical activity recommend at least 150 minutes of moderate‐to‐vigorous exercise weekly for optimal health outcomes, the distinction between concentrated and evenly distributed patterns remains unclear. We explored relationships accelerometer‐measured weekend warrior spread (MVPA) risks all‐cause, cardiovascular disease, cancer mortality. Methods Accelerometer‐based data from UK Biobank (Cohort 1 [June 8, 2013–December 30, 2015]: 89 488 individuals) US...
Abstract: Intervertebral disc degeneration (IDD) is a common musculoskeletal system disease, which one of the most important causes low back pain. Despite high prevalence IDD, current treatments are limited to relieving symptoms, and there no effective therapeutic agents that can block or reverse progression IDD. Oxidative stress, result an imbalance between production reactive oxygen species (ROS) clearance by antioxidant defense system, plays role in Polyphenols compounds inhibit ROS...
Overexpression and/or amplification of the HER2/neu gene has been shown in roughly 30% breast cancer patients. Increased levels mRNA some cell lines is partially caused by increased transcription. In MDA-MB453 human cells, an activated trans-acting factor involved transcription mediating its effects through a specific DNA region promoter. A methylation interference experiment showed novel sequence for protein–DNA interactions. Three polypeptides approximately 110, 70, and 35 kD interact with...
Abstract Background Hypertension is a major risk factor of structural brain changes, including atrophy and cerebral small vessel disease. Intracranial arteriosclerosis could be an underlying mechanism between hypertension changes. This study investigated whether intracranial carotid artery calcification (ICAC), as proxy for arteriosclerosis, explains the association changes in patients with TIA or ischemic stroke. Methods 968 (mean age 62.7 years) stroke from registry who underwent...