A5051457645- Transcranial Magnetic Stimulation Studies
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Vestibular and auditory disorders
- Neural and Behavioral Psychology Studies
- Hallucinations in medical conditions
- Neural dynamics and brain function
- Motor Control and Adaptation
- Visual perception and processing mechanisms
- Ophthalmology and Eye Disorders
- Advanced Neuroimaging Techniques and Applications
- Sleep and Wakefulness Research
- Advanced MRI Techniques and Applications
- Neurological disorders and treatments
- Neuroscience and Music Perception
- Virtual Reality Applications and Impacts
- Heart Rate Variability and Autonomic Control
- Muscle activation and electromyography studies
- Neurobiology of Language and Bilingualism
- Stroke Rehabilitation and Recovery
- Spatial Neglect and Hemispheric Dysfunction
- Sleep and Work-Related Fatigue
- Traumatic Brain Injury and Neurovascular Disturbances
- Schizophrenia research and treatment
- Optical Imaging and Spectroscopy Techniques
Université de Caen Normandie
2015-2024
Chimie Organique, Médicinale et Extractive et Toxicologie Expérimentale
2020-2024
Normandie Université
2014-2024
Cyceron
2000-2024
Inserm
2011-2024
Centre Hospitalier Universitaire de Caen Normandie
2015-2024
École Pratique des Hautes Études
2024
Centre National de la Recherche Scientifique
2000-2023
École Nationale Supérieure d'Ingénieurs de Caen
2023
GREYC
2023
The prediction of neurological outcome in comatose patients after cardiac arrest has major ethical and socioeconomic implications. purpose this study was to assess the capability serum neuron-specific enolase (NSE), a biomarker hypoxic brain damage, predict death or vegetative state cardiac-arrest survivors. We conducted prospective observational cohort one university hospital general Intensive Care Unit (ICU). All consecutive who suffered were subsequently admitted from June 2007 February...
Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is a neuropsychiatric disease characterized by an antibody-mediated autoimmune response against NMDAR. Recent studies have shown that anti-NMDAR antibodies are involved in the pathophysiology of disease. However, upstream immune and inflammatory processes responsible for this pathogenic still poorly understood. Here, we immunized mice region NMDA containing N368/G369 amino acids, previously implicated response. This paradigm induced...
Lexical and semantic retrieval was investigated in normal volunteers with PET by comparing picture confrontation naming verb generation related to the same pictures. Conjunction analysis of uncovered a common network including occipito-temporal ventral pathway for object recognition, bilateral anterior insula, SMA precentral gyrus coordination, planning overt word production. Naming highlighted two different patterns: showed specific implication Broca Wernicke's areas, whereas specifically...
Abstract One drawback of functional magnetic resonance imaging (fMRI) is that the subject must endure intense noise during testing. We examined possible role such on activation early visual cortex mental imagery. postulated may require subjects to work harder pay attention task, which in turn could alter pattern found a silent environment. To test this hypothesis, we used positron emission tomography (PET) monitor regional Cerebral Blood Flow (rCBF) six while they performed an imagery task...
See Sun et al. (doi:10.1093/aww306) for a scientific commentary on this article. About 20% of patients with ischaemic stroke have preceding transient attack, which is clinically defined as focal neurological symptoms origin resolving spontaneously. Failure to diagnose attack wasted opportunity prevent recurrent disabling stroke. Unfortunately, diagnosis can be difficult, due numerous mimics, and the absence specific test. New diagnostic tools are thus needed, in particular radiologically...
Despite extensive testing, the efficacy of low-frequency (1 Hz) repetitive transcranial magnetic stimulation (rTMS) temporo-parietal targets for treatment auditory verbal hallucinations (AVH) in patients with schizophrenia is still controversial, but promising results have been reported both high-frequency and neuronavigated rTMS. Here, we report a double-blind sham-controlled study to assess (20 rTMS applied over precise anatomical site left temporal region using neuronavigation.Fifty-nine...
Abstract Inhibitory control (IC) is a core executive function that enables humans to resist habits, temptations, or distractions. IC efficiency in childhood strong predictor of academic and professional success later life. Based on analysis the sulcal pattern, qualitative feature cortex anatomy determined during fetal life stable development, we searched for evidence interindividual differences partly trace back prenatal processes. Using anatomical magnetic resonance imaging (MRI), analyzed...
Positron emission tomography (PET) was used to investigate the functional anatomy of foveal fixation system in 10 subjects scanned under three different conditions: at rest (REST), during a central point (FIX), and while fixating same target presentation peripheral visual distractors (DIS). Compared with REST condition, both FIX DIS tasks activated common set cortical areas. First, addition involvement occipital cortex, frontal eye field (FEF) intraparietal sulcus (IPS) were bilaterally...
Background New insights have expanded the influence of vestibular system to regulation circadian rhythmicity. Indeed, hypergravity or bilateral loss (BVL) in rodents causes a disruption their daily rhythmicity for several days. The thus influences hypothalamic rhythms on Earth, which raises question whether might be altered due pathology humans. aim this study was evaluate human people presenting total comparison with control participants. Methodology and Principal Findings Nine patients...
The effect of sleep deprivation on the vestibular function is largely unknown. Some studies have found that postural balance or reflexes are decreased in sleep-deprived subjects while others no change. aim this study was to evaluate vestibulo-ocular reflex (VOR). Horizontal eye movements were recorded healthy during earth vertical axis rotation darkness once after an ordinary night and 26-29 h deprivation. In first experiment (n = 8), for which a 60 degrees s(-1) velocity step, induced...
Abstract Efforts to exclude past experiences from conscious awareness can lead forgetting. Memory suppression is central affective disorders, but we still do not really know whether emotions, including their physiological causes, are also impacted by this process in normal functioning individuals. In two studies, measured the after-effects of suppressing negative memories on cardiac response healthy participants. Results Study 1 revealed that efficient control was associated with long-term...
Normand, Hervé, Olivier Etard, and Pierre Denise.Otolithic tonic neck receptors control of limb blood flow in humans. J. Appl. Physiol. 82(6): 1734–1738, 1997.—The aim this study was to evaluate the role otolithic mechanoreceptors on cardiovascular system. We measured calf (CBF) forearm (FBF) by strain-gauge plethysmography, mean arterial pressure (MAP), heart rate (HR) 12 healthy subjects two body positions (lying prone left side) three head (reference, flexion, extension). When were lying...
Anoxic coma following cardiac arrest is a common problem with ethical, social, and legal consequences. Except for unfavorable somatosensory-evoked potentials (SSEP) results, predictors of outcome 100% specificity high sensitivity are lacking. The aim the current research was to construct clinical EEG scoring system that predicts early cortical response (N20) somatosensory evoked 6-months in comatose patients after arrest.We retrospectively reviewed records all consecutive who suffered...