A5100438091- Liver Disease Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Autophagy in Disease and Therapy
- Hepatitis B Virus Studies
- Pancreatitis Pathology and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Tracheal and airway disorders
- Acute Ischemic Stroke Management
- Peripheral Artery Disease Management
- Phagocytosis and Immune Regulation
- Trauma Management and Diagnosis
- Congenital Diaphragmatic Hernia Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Airway Management and Intubation Techniques
- Bone fractures and treatments
- Pancreatic and Hepatic Oncology Research
- Diabetes Treatment and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Coronary Artery Anomalies
- Liver Disease and Transplantation
- Histone Deacetylase Inhibitors Research
- Immunotherapy and Immune Responses
- Cerebrospinal fluid and hydrocephalus
- Cancer, Hypoxia, and Metabolism
- Animal Disease Management and Epidemiology
Shanxi Province Hospital of Traditional Chinese Medicine
2024
Liaocheng People's Hospital
2011-2023
Wuhan University
2023
Renmin Hospital of Wuhan University
2023
Pingxiang University
2023
Jilin Agricultural University
2022
North China University of Science and Technology
2022
Henan Agricultural University
2022
China Medical University
2022
Chinese Center For Disease Control and Prevention
2022
Background: The outbreak of coronavirus disease 2019 (COVID-19) has led to a large and increasing number patients requiring prolonged mechanical ventilation tracheostomy. indication optimal timing tracheostomy in COVID-19 are still unclear, the outcomes about have not been extensively reported. We aimed describe clinical characteristics with confirmed severe acute respiratory syndrome 2 (SARS-CoV-2) pneumonia who underwent elective tracheostomies. Methods: multi-center, retrospective,...
Inhibition of autophagy has been accepted as a promising therapeutic strategy in cancer, but its clinical application is hindered by lack effective and specific inhibitors. We previously identified cepharanthine (CEP) novel inhibitor, which inhibited autophagy/mitophagy through blockage autophagosome-lysosome fusion human breast cancer cells. In this study we investigated whether how inhibition affected the efficacy chemotherapeutic agent epirubicin triple negative (TNBC) cells vitro vivo....
Objective Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have shown notable advancements in managing blood sugar control. Nevertheless, there remains a gap real-world data regarding the variation acute pancreatitis (AP) risk among different GLP-1 RAs. Our study aimed to characterize and evaluate AP associated with RAs (exenatide, lixisenatide, liraglutide, albiglutide, semaglutide, dulaglutide tirzepatide) public adverse events database review relevant case reports. Methods We...
Abstract Background: Inhibiting RET kinase is a fundamental therapeutic approach for malignancies related to alterations. Despite the remarkable efficacy of pralsetinib and selpercatinib in treating various cancers, resistances due newly surfacing on-target mutations pose challenge. The emergence adaptive at solvent-front, such as G810C/S/R, coupled with occurrence concurrent both gatekeeper solvent front regions, render these medications ineffective. Furthermore, off-target VEGFR2...
We conducted environmental surveillance to detect avian influenza viruses circulating at live poultry markets (LPMs) and farms in Guangxi Autonomous Region, China, where near the China-Vietnam border. From November through April 2017-2018 2018-2019, we collected samples from 14 LPMs, 4 farms, 5 households with backyard two counties of tested for A, H5, H7, H9 by real-time reverse transcription-polymerase chain reaction (rRT-PCR). In addition, four cross-sectional questionnaire surveys among...
Human papillomavirus (HPV) vaccination is a key initiative to promote the WHO global strategy accelerate elimination of cervical cancer, and this study aimed investigate current status HPV infection genotypic characteristics population under impact age-expansion nine-valent policy in China.The clinical data 60,685 subjects who were admitted Renmin Hospital Wuhan University underwent genotyping from January 2017 October 2022 retrospectively analyzed.The total number positive included was...
Abstract The aim of our study was to describe the clinical characteristics and outcomes patients with confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia who underwent elective tracheostomies. We investigated all COVID-19 tracheostomies in intensive care units (ICUs) 23 hospitals Hubei Province, China, from January 8, 2020 March 25, 2020. Demographic information, characteristics, treatment, details tracheostomy procedure, successful weaning after tracheostomy,...
Two experiments were conducted in this research. Experiment 1 investigated the spatial expression characteristics of calcium (Ca) and phosphorus (P) transporters duodenum, jejunum, ileum 21-day-old broilers provided with adequate nutrient feed. 2 evaluated effects dietary vitamin D3 (VD3) concentration (0, 125, 250, 500, 1,000, 2,000 IU/kg) on growth performance, bone development, gene levels intestinal Ca P 1-21-day-old negative control diet without supplemental VD3. Results experiment...
Background Diabetes mellitus (DM) or cognitive impairment (CI) is known to be strongly associated with mortality. DM commonly coexists CI and proportionally increases age. However, little about the combined effect of function diabetes on This study aimed evaluate effects all-cause cause-specific mortality in Chinese older adults. Methods prospective population-based cohort was based Beijing Elderly Comprehensive Health Cohort Study. A total 4,499 adults were included. Cox’s proportional...
Vertebral artery origin anomalies are typically incidental findings during angiography. We present an extremely rare variant in which the right vertebral has a double from subclavian and common carotid association with aberrant artery, never been reported before.
The objective of this research was to study the CYP2E1 gene expression in carbon tetrachloride (CCl4)-induced acute liver injury hepatitis B virus (HBV) transgenic mice. Twenty-four HBV(-) and 24 HBV(+) mice aged 8 10 weeks were selected for present study. Intraperitoneal injection 1.0 μL/g CCl4 (1:4 dissolved olive oil) performed induce model. Eight normal clean-grade C57BL/6 taken as control group. group received saline intraperitoneally. each killed 3, 6, 12, 24, 48, 72 h after injection....
Background Endovascular thrombectomy (EVT) has evolved into the standard treatment for patients with acute ischemic stroke (AIS) and large vessel occlusion (LVO). However, little information is available on management of EVT in young AIS-LVO China. The purpose this study was to assess favorable outcomes mortality rates after 90 days Chinese their predictors. Methods This retrospective included aged 18–50 years AIS-LVO. primary efficacy endpoint modified Rankin scale (mRS) score at day 90,...