Lei He

ORCID: 0000-0001-5313-7607
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About
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Research Areas
  • Animal Nutrition and Physiology
  • Vitamin D Research Studies
  • Influenza Virus Research Studies
  • Trace Elements in Health
  • Meat and Animal Product Quality
  • Biochemical effects in animals
  • Phytochemistry and Biological Activities
  • Natural product bioactivities and synthesis
  • Crystallization and Solubility Studies
  • Phytase and its Applications
  • Pancreatic function and diabetes
  • X-ray Diffraction in Crystallography
  • Neurological Disease Mechanisms and Treatments
  • Aquaculture Nutrition and Growth
  • Traditional Chinese Medicine Analysis
  • Vaccine Coverage and Hesitancy
  • Contact Dermatitis and Allergies
  • Food composition and properties
  • FOXO transcription factor regulation
  • Drug-Induced Hepatotoxicity and Protection
  • Educational Reforms and Innovations
  • Sleep and related disorders
  • Medicinal Plant Research
  • Drug Transport and Resistance Mechanisms
  • Dental Trauma and Treatments

First Affiliated Hospital of Xinxiang Medical University
2021-2023

Shangqiu Normal University
2021-2023

Henan Normal University
2021-2023

Ludong University
2022

Xinxiang Medical University
2021

Shaoxing People's Hospital
2021

Shaoxing University
2021

Ministry of Education of the People's Republic of China
2013-2020

Xi'an Jiaotong University
2020

Air Force Medical University
2020

Abstract Context Insomnia is associated with insulin resistance (IR) in observational studies; however, whether insomnia causally IR remains unestablished. Objective This study aims to estimate the causal associations of and its related traits. Methods In primary analyses, multivariable regression (MVR) 1-sample Mendelian randomization (1SMR) analyses were performed (triglyceride-glucose index triglyceride high-density lipoprotein cholesterol [TG/HDL-C] ratio) traits (glucose level, TG,...

10.1210/clinem/dgad089 article EN The Journal of Clinical Endocrinology & Metabolism 2023-02-16

Background Anti-tuberculosis (anti-TB) drug-induced liver injury (ADLI) is one of the most common adverse effects associated with TB treatment. Cytochrome P450 (CYP) 1A1 and glutathione S-transferase (GST) P1 are important phase I/II metabolizing enzymes involved in drug metabolism detoxification. Genetic polymorphism CpG island methylation have been reported as factors influencing expression CYP1A1 GSTP1. Objective This study aimed to determine potential relationships GSTP1 polymorphisms...

10.1371/journal.pone.0119481 article EN cc-by PLoS ONE 2015-03-23

Seasonal influenza epidemic occurs every year in Guangzhou, which can affect all age groups. Young children are the most susceptible targets. Parents decide whether to vaccinate their or not based on own consideration China. The aim of this study was identify factors that important for parental decisions vaccinating against seasonal a modified health belief model (HBM).A cross-sectional conducted A total 335 parents who had at least child aged between 6 months and 3 years were recruited from...

10.4103/0366-6999.150099 article EN cc-by-nc-nd Chinese Medical Journal 2015-01-27

Sesame can trigger a systemic allergic reaction. In the present study, we investigated responses of structure and IgE binding sesame allergens to different roasting treatments (120, 150, 180 °C for 5 30 min). We analyzed tryptic digestion peptides using label-free mass spectrometry method. The total amount soluble proteins in was significantly reduced by at °C, followed 150 °C. Ses i 1 most stable protein during processing as it still possessed higher abundance compared other after under...

10.1021/acs.jafc.2c01617 article EN Journal of Agricultural and Food Chemistry 2022-07-12

The early Eocene is the warmest epoch in last 65 million years, with a global mean temperature 9 to 23°C higher than modern era. According state-of-the-art climate models, tropical rainfall contracted towards equator during this extremely warm period. However, physical mechanism causing phenomenon remains unclear. In study, we examined hemispheric energy balance that causes equatorward contraction of precipitation. A novel underlying revealed. Based on modeling CESM1.2, show...

10.5194/egusphere-egu25-18941 preprint EN 2025-03-15

Background: The aim of this study was to clarify the relationship among Rac1 expression and activation, oxidative stress β cell dysfunction in obesity. Methods: In vivo, serum levels glucose, insulin, markers were compared between ob/ob mice C57BL/6J controls. Then, these variables rechecked after administration specific inhibitor-NSC23766 mice. vitro, NIT-1 cells cultured a hyperglycemic and/or hyperlipidemic state with or without NSC23766, differences translocation, NADPH oxidase(Nox)...

10.1159/000374019 article EN cc-by-nc Cellular Physiology and Biochemistry 2015-01-01

Objective: This research aimed to evaluate the effects of age on growth, tibia development, and intestinal calcium (Ca) phosphorus (P) transporter gene expressions in broiler chickens.Methods: A total 224 male Arbor Acres broilers were fed with nutrient-adequate diets reared eight cages (28 per cage). Eight (one cage) selected killed at 5, 10, 15, 20, 25, 30, 35, 40 days age, respectively.Results: Body weight continuously increased chickens from 5 days. The bone weight, ash diameter, length...

10.5713/ab.22.0058 article EN cc-by Animal Bioscience 2022-05-02

Two experiments were conducted in this research. Experiment 1 investigated the spatial expression characteristics of calcium (Ca) and phosphorus (P) transporters duodenum, jejunum, ileum 21-day-old broilers provided with adequate nutrient feed. 2 evaluated effects dietary vitamin D3 (VD3) concentration (0, 125, 250, 500, 1,000, 2,000 IU/kg) on growth performance, bone development, gene levels intestinal Ca P 1-21-day-old negative control diet without supplemental VD3. Results experiment...

10.5187/jast.2022.e78 article EN cc-by-nc Journal of Animal Science and Technology 2022-10-21

1. This study investigated the effect of dietary calcium (Ca) levels on growth performance, bone development and Ca transporter gene expression in small intestine broiler chickens.2. On day hatch, 350, Ross 308 male broilers were randomly allotted to one five treatments with replicate pens each 14 birds per pen. Dietary feed 5.0, 7.0, 9.0, 11.0 13.0 g/kg, which 9.0 g/kg was control diet. All diets contained 4.5 non-phytate phosphorus (NPP).3. The increase from 5.0 did not affect performance...

10.1080/00071668.2021.1949697 article EN British Poultry Science 2021-06-30

1,25-Dihydroxycholecalciferol (1,25-(OH)2-D3) is the final active product of vitamin D. This study aimed to investigate effects 1,25-(OH)2-D3 on growth performance, bone development, and calcium (Ca) transporter gene expression levels in small intestine broiler chickens. On day hatching, 140 female Ross 308 broilers were randomly allotted into two treatments with five replicates (14 birds per replicate). Two (0 1.25 µg/kg) added basal diet without Results showed that addition µg/kg increased...

10.2141/jpsa.0210019 article EN cc-by-nc-sa The Journal of Poultry Science 2021-06-24

Background: Carvacrol is a monoterpenic phenol extracted from traditional Chinese herbs, including oregano and thyme. Currently, carvacrol has been widely studied for its therapeutic role in central nervous system diseases, liver diseases digestive cancer. Objective: However, the of osteosarcoma underlying molecular mechanism remain elusive. Here, we aimed to examine anticancer effects on osteosarcoma. Methods: The proliferation capacity were revealed by CCK-8 colony formation assays. Flow...

10.2174/1871520621666210901111932 article EN Anti-Cancer Agents in Medicinal Chemistry 2021-09-07

1. AOAC International, 2005. Official Methods of Analysis International. 18th Edition. Gaithersburg, MD (USA) Google Scholar

10.22358/jafs/157475/2023 article EN Journal of Animal and Feed Sciences 2023-02-03

5,6-dihy-droxy-7,8-dimeth-oxy-2-phenyl-chromen-4-one), C17H14O6, is a flavone that was isolated from the petroleum ether-soluble fraction of rare traditional Chinese medicinal herb Saussurea involucrata. The mol-ecule almost planar, with dihedral angle between planes benzo-pyran-4-one group and attached phenyl 1.89 (6)°. 5-hy-droxy forms strong intra-molecular hydrogen bond carbonyl group, resulting in six-membered hydrogen-bonded ring. 6-hy-droxy also an O-H⋯O contact. In crystal, molecules...

10.1107/s1600536813014451 article EN cc-by Acta Crystallographica Section E Structure Reports Online 2013-06-14

This study investigated the effect of calcium (Ca) and phytase interaction on growth performance bone quality in 1-42-day-old broiler chickens. A total 624 female one-day-old Ross 308 broilers were allotted to 13 treatments with four replicates 12 birds per replicate. 2 × 6 factorial experiment was designed test combinations 0.50% 1.00% Ca 0, 500, 1,000, 2,500, 5,000, 10,000 FTU/kg basal diet (0.25% non-phytate phosphorus, NPP). The control contained adequate phosphorus (P). Dietary Ca,...

10.1590/1806-9061-2021-1568 article EN cc-by Brazilian Journal of Poultry Science 2022-01-01

Objective To explore the effect of safflower yellow pigment on serum level SOD,MDA and CAT in acute cerebral infarction.Methods One hundred twenty-one cases infarction were selected from November 2007 to 2009,and randomly divided into observation group control group.The routine therapy was used group,and basis therapy,safflower lyophilized powder(100 mg) group,one time a day.The course two groups 14 days.Before after treatment,Chinese stroke scale(CSS)and National Institutes Health Stroke...

10.3760/cma.j.issn.1674-4756.2011.08.022 article EN Central Plains Medical Journal 2011-04-25

HMIPv6 remedied the deficiency of mobile IPv6 protocol, reduced delay and amount signaling during handover compared with basic MIPv6. But duplicate address detection transmission time for operation in could cause high delay. So still cannot reach requirement traffic that is sensitive, such as voice. Through analysis HMIPv6, a kind optimized managing models routing on basis hierarchical mechanisms was proposed. By NS-2 simulation, we present analyze performance testing our proposal by...

10.1109/wicom.2008.993 article EN 2008-10-01
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