A5101446291- Gut microbiota and health
- Scoliosis diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Pelvic and Acetabular Injuries
- Hospital Admissions and Outcomes
- Chronic Lymphocytic Leukemia Research
- Clostridium difficile and Clostridium perfringens research
- Spine and Intervertebral Disc Pathology
- Probiotics and Fermented Foods
- Ion channel regulation and function
- Electrochemical Analysis and Applications
- Retinal Diseases and Treatments
- Pharmacological Effects of Natural Compounds
- Hip and Femur Fractures
- COVID-19 and healthcare impacts
- Sepsis Diagnosis and Treatment
- Retinal Development and Disorders
- Nanopore and Nanochannel Transport Studies
- Trauma and Emergency Care Studies
- Gallbladder and Bile Duct Disorders
- IL-33, ST2, and ILC Pathways
- Retinopathy of Prematurity Studies
- Autoimmune and Inflammatory Disorders
- Nerve injury and regeneration
- Eosinophilic Esophagitis
Hospital for Sick Children
2019-2025
University of Toronto
2010-2024
SickKids Foundation
2023
Children's Hospital of Philadelphia
2017-2020
University of Pennsylvania
2018
Philadelphia University
2018
Johns Hopkins Medicine
2015
Johns Hopkins University
2015
Cornell University
2013
Feinstein Institute for Medical Research
2011-2012
Diabetic retinopathy (DR) is a leading cause of blindness in working age adults. The objective this study to investigate the effects vascular endothelial growth factor receptor 1 (VEGFR1) blockade on complications DR. Experimental models diabetes were induced with streptozotocin (STZ) treatment or Insulin2 gene mutation (Akita) mice. Protein expression and localization examined by western blots (WB) immunofluorescence (IF). mRNA was quantified PCR array real-time PCR. activity VEGFR1...
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is an antibiotic resistance threat of the highest priority. Given limited treatment options for this multidrug-resistant organism (MDRO), there urgent need targeted strategies to prevent transmission.
Background: Adolescent idiopathic scoliosis (AIS) is the most prevalent pediatric spinal condition. During growth, moderate treated with a brace to minimize risk of progression surgical range. However, minority patients meet indications, greater number presenting late, already appropriate for surgery. This study determines treatment cost differential between candidates and late-presenting within public health care setting. Methods: retrospective review 373 consecutive AIS seen initial...
To describe the provision of weekend physiotherapy (PT) services in tertiary-care hospitals Canada.A prospective cross-sectional survey was conducted across hospitals, defined as those with university affiliation and at least one intensive care unit (ICU). Data were collected via telephone-administered questionnaires addressing hospital demographics, staffing, workload, referral criteria.A response rate 84% (n=36) obtained. Of facilities providing PT (97%), 35 (100%) provided on Saturdays,...
Idiopathic chronic enterocolitis (ICE) is one of the most commonly encountered and difficult to manage diseases captive rhesus macaques ( Macaca mulatta ). The etiology not well understood, but perturbations in gut microbial communities have been implicated. Here we evaluated effects a 14-day course vancomycin, neomycin, fluconazole on animals affected with ICE, comparing treated, untreated, healthy animals. We performed microbiome analysis duodenal colonic mucosal samples feces order probe...
Background: The COVID-19 pandemic has affected healthcare worldwide since December 2019. We aimed to identify the effect of on outpatient clinic and surgical volumes peri-operative complications for pediatric spinal deformities patients. Methods: In this multi-center retrospective study, visits (in-person virtual care) spine surgeries in four high-volume centers were compared between March 2019 same period 2020. Peri-operative collected periods. Descriptive statistics calculated, comparative...
# Abstract 57. Radiographic reporting in adolescent idiopathic scoliosis: Is there a discrepancy comparing radiologists’ reports and surgeons’ assessments? {#article-title-2} Cobb angle measurement is the standard method for quantification of scoliosis (AIS),
Purpose: To describe the provision of weekend physiotherapy (PT) services in tertiary-care hospitals Canada. Methods: A prospective cross-sectional survey was conducted across hospitals, defined as those with university affiliation and at least one intensive care unit (ICU). Data were collected via telephone-administered questionnaires addressing hospital demographics, staffing, workload, referral criteria. Results: response rate 84% (n=36) obtained. Of facilities providing PT (97%), 35...