A5101432613- Circular RNAs in diseases
- MicroRNA in disease regulation
- Magnetic Properties of Alloys
- Cancer-related molecular mechanisms research
- Rare-earth and actinide compounds
- Freshwater macroinvertebrate diversity and ecology
- Insect-Plant Interactions and Control
- RNA modifications and cancer
- RNA Research and Splicing
- Insect Resistance and Genetics
- Hemiptera Insect Studies
- Fish Ecology and Management Studies
- Physiological and biochemical adaptations
- Phytoplasmas and Hemiptera pathogens
- Histone Deacetylase Inhibitors Research
- Environmental DNA in Biodiversity Studies
- Neurobiology and Insect Physiology Research
- Invertebrate Immune Response Mechanisms
- Magnetic and transport properties of perovskites and related materials
- Calpain Protease Function and Regulation
- Aquaculture Nutrition and Growth
- Fatigue and fracture mechanics
- Signaling Pathways in Disease
- Galectins and Cancer Biology
- Insect symbiosis and bacterial influences
Tianjin Normal University
2020-2025
Shandong Normal University
2025
Hebei Medical University
2023-2024
First Affiliated Hospital of Henan University
2024
Zhengzhou University
2018-2023
Guangzhou Medical University
2020
Nankai University
2017-2018
Sun Yat-sen University
2018
Suzhou Vocational Health College
2010-2012
National Cancer Institute
2001-2002
Abstract The phylogeny of true bugs (Hemiptera: Heteroptera), one the most diverse insect groups in terms morphology and ecology, has been focus attention for decades with respect to several deep nodes between suborders Hemiptera infraorders Heteroptera. Here, we assembled a phylogenomic data set 53 taxa 3102 orthologous genes investigate Hemiptera–Heteroptera, both concatenation coalescent methods were used. A binode‐control approach filtering was introduced reduce incongruence different...
A growing number of long non-coding RNAs (lncRNAs) have been found to be involved in diverse biological processes such as cell cycle regulation, embryonic development, and differentiation. However, limited knowledge is available concerning the underlying mechanisms lncRNA functions. In this study, we down-regulation TCONS_00041960 during adipogenic osteogenic differentiation glucocorticoid-treated bone marrow mesenchymal stem cells (BMSCs). Furthermore, up-regulation promoted expression...
More than 95% of phytophagous true bug (Hemiptera: Heteroptera) species belong to four superfamilies: Miroidea (Cimicomorpha), Pentatomoidea, Coreoidea, and Lygaeoidea (all Pentatomomorpha). These iconic groups highly diverse, overwhelmingly insects include several economically prominent agricultural silvicultural pest species, though their evolutionary history has not yet been well resolved. In particular, superfamily- family-level phylogenetic relationships these lineages have remained...
Abstract A growing amount of evidence has shown that long noncoding RNAs (lncRNAs) play crucial roles in osteosarcoma (OS). However, little knowledge is available about the functional and molecular mechanisms lncRNA Alu‐mediated p21 transcriptional regulator (APTR) OS. Herein, APTR expression was demonstrated to be significantly upregulated OS tumor tissues four cell lines (including MG63, 143B, Saos‐2, HOS) compared with adjacent human osteoblast line hFOB1.19, respectively. We confirmed...
Long-term exposure of humans to air pollution is associated with an increasing risk cardiovascular diseases (CVDs). Astaxanthin (AST), a naturally occurring red carotenoid pigment, was proved have multiple health benefits. However, whether or not AST also exerts protective effect on fine particulate matter (PM2.5)-induced cardiomyocyte damage and its underlying mechanisms remain unclear.In vitro experiments, the H9C2 cells were subjected pretreatment varying concentrations AST, then injury...
Rabdosiae rubescentis herba (Isodon rubescens) is widely used as a folk medicine to treat esophageal cancer and sore throat in China. Its germplasm resources are abundant China, with I. rubescens (Hemsl.) Hara f. lushanensis 2 typical forms. featured by biosynthesis of the diterpenoid oridonin strong anticancer activity, while produces another lushanrubescensin. However, biosynthetic pathways both still need be fully understood. In particular, little known about genetic background lushanensis.
Prostate specific antigen, the clinical marker for prostate cancer, is a neutral serine protease whose function to lyse seminal proteins. Recent work by our laboratory has suggested that antigen stimulates generation of reactive oxygen species in cancer cells. Using 2',7'-dichlorofluorescin diacetate, dye fluoresces presence hydrogen peroxide or hydroxyl radicals, we found markedly stimulated LNCaP The effect was concentration dependent and its specificity supported fact anti-prostate...
Background: This study was designed to research the potential function of lncRNA ANRIL in osteosarcoma (OS). Materials and methods: Quantitative real-time PCR, cell counting kit-8, wound healing assay, Transwell flow cytometric analysis, caspase activity Western blot were carried out. Results: remarkably upregulated human OS tissues cells, knockdown significantly suppressed MG63 proliferation, migration, invasion promoted apoptosis. Moreover, our mechanistic findings verified that...
Aging is a complex biological process that progressively impairs cellular functionality and overall health across organisms. Transmission control mechanisms, vital for intercellular communication organ homeostasis, are significantly affected by this decline. Current research highlights aging disrupts ion channels, synaptic plasticity, protein trafficking, contributing to dysfunction age-related diseases like neurodegeneration cardiovascular issues. Advances have pinpointed molecular changes...
Members of the family Scutelleridae (Heteroptera: Pentatomomorpha: Pentatomoidea) are also called shield bugs because greatly enlarged scutellum, or jewel brilliant colours many species. All scutellerids phytophagous, feeding on various parts their host plants. Due to lack obvious synapomorphies and failure apply rigorous phylogenetic methods, higher classification has been disputed for more than 150 years. Here we reconstructed a phylogeny based complete sequences 18S 28S nuclear rDNAs all...
Persistent infection with hepatitis B virus (HBV) accounts for the majority of hepatocellular carcinoma (HCC), but molecular mechanisms underlying liver carcinogenesis are still not completely understood. Increasing evidence demonstrates that microRNAs (miRNAs) play significant functional roles in virus-host interactions. The aim this study was to explore differentially expressed miRNA profiles and investigate mechanism miR-0308-3p HBV-positive HCC carcinogenesis.High-throughput sequencing...
Abstract MicroRNA‐17‐5p (miR‐17‐5p) and epithelial‐mesenchymal transition (EMT) have been reported to participate in the development progression of multiple cancers. However, relationship between miR‐17‐5p EMT osteosarcoma (OS) is still poorly understood. This study was investigate effects its potential mechanism regulating proliferation, apoptosis, human OS. Quantitative real‐time PCR used detect SRC kinase signaling inhibitor 1 (SRCIN1) messenger RNA expression OS specimens cell lines....
Abstract Chironomidae species are universally used for studying the impact of pollutants in aquatic systems. The nonbiting midge Propsilocerus akamusi is often found urban streams and suitable use as a toxicological bioindicator. However, few studies have previously examined metal stress this species. We sequenced genome to address question. Here, we present first chromosome‐level P . , obtained from Illumina short‐read PacBio long‐read sequences with Hi‐C technology. size very small...
Although the executive pathways of senescence are known, underlying control mechanisms diverse and not fully understood, particularly how cancer cells avoid triggering despite experiencing exacerbated stress conditions within tumor microenvironment.Mass spectrometry (MS)-based proteomic screening was used to identify differentially regulated genes in serum-starved hepatocellular carcinoma RNAi employed determine knockdown phenotypes prioritized genes. Thereafter, gene function investigated...
The crystallographic and magnetic structures of at 77 K have been refined by Rietveld analysis the high-resolution neutron powder diffraction data. indicates that has -type structure (). Cr atoms occupy 12j, 6g 4f sites with occupancies 0.12, 0.10 0.50 respectively, but are absent 12k sites. moments all lie in plane perpendicular to sixfold axes exhibit planar anisotropy. relations between interesting abnormal properties discussed.
The magnetic structure of Nd6Fe13 Si has been studied by magnetization measurement, the singular point detection technique and neutron powder diffraction. It was found that Nd6Fe13Si is ferrimagnetic with a compensation temperature 357 K Curie 441 K. spontaneous values are 12.9 J T-1 kg-1 at 5 7.4 300 There two B0cr1 B0cr2 phase transition field below 225 K: B0cr1=6.2 T B0cr2=8.2 77 B0cr=5.3 atomic moments ordered in an antiparallel manner, magnetosublattices MI up arrow (8f(Nd), 16l(Nd),...
To explore the mechanisms underlying pro-apoptotic effects of synthetic retinoid N-4-(hydroxyphenyl)retinamide (4-HPR) on LNCaP human prostate cancer cells, we used differential display-polymerase chain reaction (DD-PCR) technique to identify 4-HPR-responsive genes. RNA extracted from cells that had been treated for 24 h with 4-HPR at a dose (2.5 microM) optimal apoptosis induction was DD-PCR analysis using random primers. A differentially expressed 115 bp fragment cloned and sequenced then...
Cancer cells use glucose via glycolysis to maintain tumor cell proliferation. However, the effect of long non‑coding RNAs (lncRNAs) on in osteosarcoma (OS) remains unclear. The present study aimed investigate involvement lncRNA XLOC_005950/hsa‑microRNA (miR)‑542‑3p/phosphofructokinase, muscle (PFKM) axis regulation metabolism, proliferation and apoptosis progression OS. XLOC_005950, hsa‑miR‑542‑3p PFKM expression OS tissues was detected reverse transcription‑quantitative PCR analysis....
The aim of the present study was to investigate effects microRNA (miR)-183 on vitality, invasion, metastasis and apoptosis in osteosarcoma (OS) cells, mediated by its binding metastasis-associated protein 1 (MTA1). A dual luciferase reporter assay performed determine whether MTA1 a direct target miR-183. Cell Counting Kit-8, Transwell, scratch-wound healing, fluorescence-activated cell sorting andterminal deoxynucleotidyl transferase dUTP nick end labeling assays were also miR-183 expression...
(1) Background: At present, cancer cell metastasis is the main cause of death in patients with malignant tumors, and up to 23% osteosarcoma have died due lung lymph node metastasis. Therefore, finding new molecules involved tumor development can provide strategies for diagnosis treatment patients. Circular RNAs (circRNAs) are a type RNA molecule that connected head-to-tail form closed ring. There increasing evidence circRNAs many biological functions various diseases. However, role mechanism...