A5100691473- Heme Oxygenase-1 and Carbon Monoxide
- Alcohol Consumption and Health Effects
- Intracerebral and Subarachnoid Hemorrhage Research
- Neonatal Health and Biochemistry
- Cancer-related molecular mechanisms research
- Acute Ischemic Stroke Management
- Neurological Disease Mechanisms and Treatments
- Cystic Fibrosis Research Advances
- MicroRNA in disease regulation
- Venous Thromboembolism Diagnosis and Management
- Advanced Glycation End Products research
- Energy, Environment, Economic Growth
- Hemoglobin structure and function
- Cleft Lip and Palate Research
- Immune Response and Inflammation
- Plant Pathogens and Fungal Diseases
- Circular RNAs in diseases
- Stroke Rehabilitation and Recovery
- Bone Metabolism and Diseases
- Genomics and Rare Diseases
- TGF-β signaling in diseases
- Sphingolipid Metabolism and Signaling
- Sustainable Industrial Ecology
- Inflammation biomarkers and pathways
- Kruppel-like factors research
Xinxiang Medical University
2012-2023
First Affiliated Hospital of Xinxiang Medical University
2019-2023
National Academy of Governance
2022
Children's Hospital of Fudan University
2021-2022
Chinese Academy of Governance
2022
Henan Psychiatric Hospital
2013-2022
Griffith University
2022
Peking University
2022
Shandong University
2022
First Hospital of China Medical University
2022
Abstract During bacterial infection, the bone marrow hematopoietic activity shifts toward granulocyte production, which is critical for host defenses. Along with this enhancement of granulopoiesis, also increases its release precursors. At present time, little known about commitment precursor cells, including stem cells and progenitors, in response. To investigate cell response to bacteremia was established Balb/c mice by i.v. injection Escherichia coli. Bacteremia caused a 10-fold increase...
Follistatin-like protein 1 (FSTL1) is a proinflammation mediator implicated in arthritis rodent animal models. The present study aimed at assessing FSTL1 levels systemic autoimmune diseases and correlating them with disease activity patients rheumatoid (RA). Serum from 487 69 healthy individuals were measured by enzyme-linked immunosorbent assay (ELISA). expression synovial fluid (SF) tissues (STs) was determined ELISA, immunohistochemistry, real-time polymerase chain reaction (RT-PCR)...
Objective: The drug-loaded PEGylated nanomaterials have shown effective cell-killing in vitro, but to the best of authors' knowledge there been no reports successful drug delivery vitro and vivo using polyethyleneglycol-2000-distearoyl phosphatidyl ethanolamine (PEG2000-DSPE) loaded with unmodified molecules, such as quercetin (QUE). In this study, it remained an open question whether formulations could prove vivo, study distribution clearance PEG-DPSE-ylated lipid-based nanoliposomes...
Esophageal cancer is one of the most aggressive cancers in world, 70 % which are from China and esophageal squamous cell carcinoma (ESCC) major histopathological form (>90 %). The single nucleotide polymorphisms (SNPs) mature sequence microRNA (miRNA) (mmSNPs) could cause alteration expression contribute to susceptibility cancers. To evaluate association between mmSNPs ESCC, a case-control study including 773 patients with ESCC 882 gender- age-matched controls was carried out investigate...
Triple-negative breast cancer (TNBC) is defined by the lack of expression estrogen receptor (ER), progesterone (PR) and human epidermal growth factor 2 (HER2). It characterized aggressive behavior, poor prognosis targeted therapies. MicroRNA (miRNA) as a novel modulator gene has played an important regulatory role in malignancy. Dysregulation and/or mutation miRNAs may also contribute to TNBC susceptibility since it associated with ER, PR HER2. Single nucleotide polymorphisms (SNPs) be...
Fungal infections have been increasing and life-threatening in recent years, but host immune responses, especially the humoral immunity, to fungi not fully understood. In present study, we report that natural antibodies from unimmunized mice bind Candida albicans. We established a monoclonal antibody, 3B4, which recognized surface antigen located at germ tubes of C. The 3B4 antibody protected albicans-induced death passive immunization, by mechanisms involving suppressing tube formation...
Delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) is more characteristic of anoxic than other types anoxia. Those who have the same degree and are similar age gender a greater risk getting DEACMP. This has made it clear that there obvious personal differences. Genetic factors may play very important role. The authors performed genome-wide association study involving pooling DNA obtained from 175 patients 244 matched without delayed controls. Illumina HumanHap 660 Chip...
The effects of different hormones and their concentration combinations, explant types, dark periods, on the regeneration grape ‘Wink’ was investigated using in vitro leaves, petioles, internodes radicles. results showed that all media prepared, explants following produced highest rate: 78.74±1.60% leave medium prepared with MS+18.20 μM,TDZ+0.49 μM IBA regenerated a mean 6.75±0.75 shoots per explant; 39.33±1.47% petioles MS+9.10 TDZ+0.49 3.55±0.50 41.37±1.13% same 4.74±0.64. However, radicles...
Objective: The influence of vaspin on vascular health had been investigated, yielding conflicting results. This study is intended to investigate the relation between and stroke severity outcome in a cohort Chinese patient with acute ischemic (AIS).Methods: was prospective single-center observational Xinxiang, China. From 1 July 2017 30 November 2019, all patients first-ever AIS were consecutively included. Serum levels vaspin, at (assessed by NIHSS score) admission functional modified Rankin...
The aim of this study is to explore the relationship between neuron-specific enolase (NSE) gene polymorphism and delayed encephalopathy after acute carbon monoxide poisoning (DEACMP) provide a theoretical basis for DEACMP pathogenesis, diagnosis, prognosis. To investigate relationship, we screened 6 NSE single nucleotide polymorphisms (SNPs), based on results previous genome-wide association studies (GWAS). A total 1,201 patients, including 416 in group 785 (ACMP) group, were detected by...
Background Inverted nipples are a common problem in female patients. This deformity impairs the function and appearance of breast may cause psychological distress. Existing correctional techniques result nipple necrosis, recurrence, infection, scarring. In this study, we evaluated efficacy minimally invasive inverted correction method involving an adjustable-traction device designed by authors. Methods All patients who underwent at authors’ hospital from April 2003 to March 2014 were...
The temperature dependence of methionine ligand dissociation and rebinding dynamics in cytochrome c aqueous solution has been studied using classical molecular simulation. Results are compared with previous study at 300 K water order to understand how the change protein environment underlying energy landscape influence dynamics. Rebinding 77, 180, exhibits changes both time scale mechanism as solvent undergo a dynamic "glass transition". At each temperature, yields subset trajectories that...
IL-12 inhibition of the endothelial cell functions and angiogenesis is mediated by cross-talk between lymphocyte cells, which plays a key role in inhibiting process eyeballs malignant tumors.
We explored the association of leucine-rich repeats and calponin homology domain containing 1 (LRCH1) gene polymorphisms with genetic susceptibility to delayed encephalopathy after acute carbon monoxide poisoning (DEACMP), which might provide a theoretical basis for pathogenesis, diagnosis, prognosis research DEACMP.Four single nucleotide polymorphisms, rs1539177 (G/A), rs17068697 rs9534475 (A/C), rs2236592 (T/C), LRCH1, selected as candidate genes through genome-wide analysis, were...