A5014612151- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Risk Factors
- Nutritional Studies and Diet
- Sodium Intake and Health
- Global Public Health Policies and Epidemiology
- Obesity, Physical Activity, Diet
- Hemodynamic Monitoring and Therapy
- Non-Invasive Vital Sign Monitoring
- Heart Rate Variability and Autonomic Control
- Optical Imaging and Spectroscopy Techniques
- Cardiovascular Health and Disease Prevention
- Pharmaceutical Economics and Policy
- Cardiac Valve Diseases and Treatments
- Gene expression and cancer classification
- Cell Adhesion Molecules Research
- Healthcare Policy and Management
- Air Quality and Health Impacts
- Bioinformatics and Genomic Networks
- Angiogenesis and VEGF in Cancer
- Aortic Disease and Treatment Approaches
- Acute Myocardial Infarction Research
- Atmospheric chemistry and aerosols
- Mitochondrial Function and Pathology
- Health disparities and outcomes
- Platelet Disorders and Treatments
University of Washington
2010-2025
Seattle University
2011-2025
Stanford University
1995-2024
Sungkyunkwan University
2024
Eugene Research Institute
2023
University of California, Irvine
2018
University of Washington Medical Center
2014-2015
Khoo Teck Puat Hospital
2014
Yonsei University
2006
Agilent Technologies (United States)
2003
Background— Apelin is among the most potent stimulators of cardiac contractility known. However, no physiological or pathological role for apelin–angiotensin receptor-like 1 (APJ) signaling has ever been described. Methods and Results— We performed transcriptional profiling using a spotted cDNA microarray with 12 814 unique clones on paired samples left ventricle obtained before after placement ventricular assist device in 11 patients. The significance analysis microarrays novel rank...
BACKGROUND: Cardiovascular disease (CVD) risk differs across Asian subgroups, possibly due to differences in hypertension burden. We characterized lifetime blood pressure (BP) trajectories for East and South individuals compared their associations with CVD risk. METHODS: Among 148 872 UK Biobank participants primary care utilization data, life course BP were fitted as a function of age by sex according self-identified ethnicity. determined time-averaged young adulthood (18–39 years), middle...
To gain fundamental information regarding the molecular basis of endothelial cell adhesive interactions during vascular formation, we have cloned and characterized a unique adhesion molecule. This molecule, named cell-selective molecule (ESAM), is new member immunoglobulin superfamily. The conceptual protein encoded by cDNA clones consists V-type C2-type domains as well hydrophobic signal sequence, single transmembrane region, cytoplasmic domain. Northern blot analysis showed ESAM to be...
Large-scale gene expression studies provide significant insight into genes differentially regulated in disease processes such as cancer. However, these investigations offer limited understanding of multisystem, multicellular diseases atherosclerosis. A systems biology approach that accounts for interactions, incorporates nontranscriptionally genes, and integrates prior knowledge offers many advantages. We performed a comprehensive level assessment coronary atherosclerosis using 51 artery...
Social determinants of health (SDOH) play a significant role in the development cardiovascular risk factors. We investigated SDOH associations with factors among Asian American subgroups.
Vascular endothelial cells maintain the interface between systemic circulation and soft tissues mediate critical processes such as inflammation in a vascular bed-selective fashion. To expand our understanding of genetic pathways that underlie these specific functions, we have focused on identification novel genes are differentially expressed all cells, well restricted groups this cell type. Virtual subtraction was conducted employing gene expression data deposited public databases 384...
Ultra-processed food (UPF) consumption is linked to adverse health outcomes, including cardiovascular disease and all-cause mortality. Asian Americans (AAs) are the fastest growing ethnic group in United States, yet their dietary patterns have seldom been described. The aim was characterize UPF among AAs determine whether acculturation associated with increased consumption. NHANES an annual, cross-sectional survey representative of US population. We examined 2011–2018 data, which included...
Most research examining the association between blood pressure (BP) and cardiovascular disease (CVD) is sex-agnostic. Our goal was to assess sex-specific associations BP CVD mortality.
This cross-sectional study aims to better understand the heterogeneous associations of acculturation level on CV risk factors among disaggregated Asian subgroups. We hypothesize that association between and will differ significantly by subgroup.We used National Health Interview Survey (NHIS), a nationally representative US survey, years 2014-18. Acculturation was defined using: (a) in US, (b) citizenship status, (c) English proficiency. created an index, categorized into low vs. high (scores...