- Microbial Community Ecology and Physiology
- Graphene research and applications
- Topological Materials and Phenomena
- Renin-Angiotensin System Studies
- Extracellular vesicles in disease
- MXene and MAX Phase Materials
- MicroRNA in disease regulation
- Advancements in Battery Materials
- Microbial Natural Products and Biosynthesis
- Genomics and Phylogenetic Studies
- Atomic and Subatomic Physics Research
- Boron and Carbon Nanomaterials Research
- Advanced Battery Materials and Technologies
- Angiogenesis and VEGF in Cancer
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Selenium in Biological Systems
- Polar Research and Ecology
- Advanced Photocatalysis Techniques
- Dark Matter and Cosmic Phenomena
- Studies on Chitinases and Chitosanases
- Trace Elements in Health
- Acute Myeloid Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Osteoarthritis Treatment and Mechanisms
- Gas Sensing Nanomaterials and Sensors
Central South University
2013-2025
First Affiliated Hospital of Chengdu Medical College
2025
Chengdu Medical College
2025
Huazhong University of Science and Technology
2023-2025
China Southern Power Grid (China)
2018-2024
Xi'an Jiaotong University
2014-2024
Key Laboratory of Guangdong Province
2024
Methodist Hospital
2020-2024
Chongqing Medical University
2023-2024
Children's Hospital of Chongqing Medical University
2023-2024
The higher-order topological phases have attracted intense attention in the past years, which reveals various intriguing properties. Meanwhile, enrichment of group symmetries with projective symmetry algebras redefines fundamentals matter and makes Stiefel-Whitney (SW) classes classical wave systems possible. Here, we report experimental realization nodal loop semimetal an acoustic system obtain inherent SW invariants. In stark contrast to semimetals relating complex vector bundles, hinge...
Abstract The discovery of higher‐order topological insulator metamaterials, in analogy with their condensed‐matter counterparts, has enabled various breakthroughs photonics, mechanics, and acoustics. A common way inducing wave phenomena is through pseudo‐spins, which mimic the electron spins as a symmetry‐breaking degree freedom. Here, this work exploits degenerate orbitals acoustic resonant cavities to demonstrate versatile, orbital‐selective, corner states. Type‐II states are theoretically...
Deep-sea hydrothermal vents are one of the most unique and fascinating ecosystems on Earth. Although phylogenetic diversity vent communities has been extensively examined, their physiological is poorly understood. In this study, a GeoChip-based, high-throughput metagenomics technology revealed dramatic differences in microbial metabolic functions newly grown protochimney (inner section, Proto-I; outer Proto-O) section mature chimney (4143-1) at Juan de Fuca Ridge. Very limited numbers...
Oxidative stress-induced endothelial dysfunction plays a key role in ischemia/reperfusion injury. Recent evidence indicates that progenitor cell-derived microvesicles (EPC-MVs) can promote angiogenesis of cells (ECs). Here, we investigated the potential effects EPC-MVs on hypoxia/reoxygenation (H/R) injury human brain microvascular ECs (hb-ECs). MVs were prepared from EPCs cultured serum deprivation (SD) medium (starving stress, sEPC-MVs) or SD containing tumor necrosis factor- α (TNF )...
Two-dimensional layered materials commonly face hindered electron transfer and poor structure stability, thus limiting their application in high-rate long-term sodium ion batteries. In the current study, we adopt finite element simulation to guide rational design of nanostructures. By calculating von Mises stress distribution a series carbon materials, find that hollow biconcave could effectively alleviate concentration resulting from expansion. Accordingly, propose biconcave-alleviated...
Two Shewanella -like bacterial strains, WP2 T and WP3 , which were isolated from west Pacific deep-sea sediment, studied to determine their taxonomic position. Cells of the two bacteria facultatively anaerobic, Gram-negative rods motile by means a single polar flagellum. Strain was psychrophilic, growing optimally at about 10–15 °C, whereas strain psychrotolerant, 15–20 °C. The strains grew in pressure range 0.1–50 MPa, with optimal growth 20 MPa. able use nitrate, fumarate, trimethylamine N...
Angiotensin-converting enzyme 2 (ACE2) is a lately discovered catalyzing Angiotensin II into 1-7. has been reported to impair endothelial progenitor cell (EPC) function and detrimental stroke. Here, we studied the role of ACE2 in regulating EPC vitro vivo. EPCs were cultured from human renin angiotensinogen transgenic (R+A+) mice their controls (R-A-). In experiments, transduced with lentivirus-ACE2 or lentivirus-green fluorescence protein. The effects overexpression on NO synthase...
Cell-released microvesicles (MVs) represent a novel way of cell-to-cell communication. Previous evidence indicates that endothelial progenitor cells (EPCs)-derived MVs can modulate cell survival and proliferation. In this study, we evaluated whether EPC-MVs protect cardiomyocytes (CMs) against angiotensin II (Ang II)-induced hypertrophy apoptosis. The H9c2 CMs were exposed to Ang in the presence or absence EPC-MVs. Cell viability, apoptosis, surface area β-myosin heavy chain (β-MHC)...
Abstract Topological phases of matter have attracted significant attention in recent years, due to the unusual robustness their response defects and disorder. Various research efforts been exploring classical quantum topological wave phenomena engineered materials, which different degrees freedom (DoFs) – for most part based on broken crystal symmetries associated with pseudo-spins induce synthetic gauge fields that support unveil distinct forms propagation. However, spin is not only viable...
Abstract Neurotransmitters are key modulators in neuro-immune circuits and have been linked to tumor progression. Medullary thyroid cancer (MTC), an aggressive neuroendocrine tumor, expresses neurotransmitter calcitonin gene-related peptide (CGRP), is insensitive chemo- radiotherapies, the effectiveness of immunotherapies remains unknown. Thus, a comprehensive analysis microenvironment would facilitate effective therapies provide evidence on CGRP’s function outside nervous system. Here, we...
A sediment core spanning approximately 1,600 years was collected from a lake on Ardley Island, Antarctica. The had been greatly influenced by penguin guano. Using molecular methods, the chitinolytic bacterial community along studied over its entire length. Primers targeting conserved sequences of catalytic domains family 18 subgroup chitinases detected group wide taxonomic range bacteria. quantitative competitive PCR (QC-PCR), chitinase gene copies in each 1-cm section whole column were...
This study investigated the role of stromal cell-derived factor-1α (SDF-1α)/CXC chemokine receptor 4 (CXCR4) axis in brain and endothelial progenitor cells (EPCs), explored efficacy CXCR4 primed EPCs treating ischemic stroke diabetes. The db/db diabetic db/+ mice were used this study. Levels plasma SDF-1α circulating CD34+CXCR4+ measured. Brain expression quantified at basal after middle cerebral artery occlusion (MCAO). In vitro study, transfected with adenovirus carrying null (Ad-null) or...
Protection of cerebral endothelial cells (ECs) from hypoxia/reoxygenation (H/R)-induced injury is an important strategy for treating ischemic stroke. In this study, we investigated whether co-culture with progenitor (EPCs) and neural (NPCs) synergistically protects ECs against H/R the underlying mechanism. EPCs NPCs were respectively generated inducible pluripotent stem cells. Human brain used to produce in vitro H/R-injury model. Data showed: 1) Co-culture inhibited H/R-induced reactive...
T-cell-based immunotherapy is gaining momentum in cancer treatment; however, our comprehension of the transcriptional regulation governing T cell antitumor activity remains constrained. The objective this study was to explore function interferon regulatory factor 4 (IRF4) CD8 + cells using TRAMP-C1 prostate and B16F10 melanoma model. To achieve this, we generated an Irf4 GFP-DTR mouse strain discovered that tumor-infiltrating lymphocytes (TILs) expressing high levels IRF4.GFP exhibited a...
Rh, Ru, Pt or Pd doping on MnOx–CeO<sub>2</sub>/graphene catalysts increased the amount of chemisorbed oxygen and surface acid sites.