A5090856147- RNA Interference and Gene Delivery
- Cardiovascular Health and Risk Factors
- Cancer-related molecular mechanisms research
- Advanced biosensing and bioanalysis techniques
- Renal and related cancers
- Cardiac Health and Mental Health
- Acupuncture Treatment Research Studies
- Metabolomics and Mass Spectrometry Studies
- MXene and MAX Phase Materials
- RNA modifications and cancer
- Spinal Cord Injury Research
- Sexual function and dysfunction studies
- Cancer, Hypoxia, and Metabolism
- Circular RNAs in diseases
- Animal Virus Infections Studies
- High Altitude and Hypoxia
- MicroRNA in disease regulation
- Pain Mechanisms and Treatments
- Ferroptosis and cancer prognosis
- Neurogenesis and neuroplasticity mechanisms
- Nerve injury and regeneration
- Renal cell carcinoma treatment
- RNA Research and Splicing
- SARS-CoV-2 and COVID-19 Research
- Hormonal and reproductive studies
Chongqing Medical University
2024-2025
Urology San Antonio
2016
University of California, San Francisco
2012-2016
Nanjing Drum Tower Hospital
2009
Tsinghua University
2004-2005
Abstract Background Clear cell renal carcinoma (ccRCC) is the most prevalent kidney cancer with high aggressive phenotype and poor prognosis. Accumulating evidence suggests that circRNAs have been identified as pivotal mediators in cancers. However, role of ccRCC progression remains elusive. Methods The differentially expressed 4 paired human adjacent noncancerous tissues were screened using circRNA microarrays candidate target was selected based on expression level weighted gene correlation...
SARS-CoV (the SARS-Associated Coronavirus) was reported as a novel virus member in the coronavirus family, which cause of severe acute respiratory syndrome. Coronavirus replication occurs through unique mechanism employing Leader sequence transcripts when initiating transcription from genome. Therefore, we cloned SARS-CoV(BJ01), is identical to that identified SARS-CoV(HKU-39849), and constructed specific siRNA targeting sequence. Using EGFP RFP reporter genes fused with sequence,...
Clear cell renal carcinoma (ccRCC) is the most prevalent kidney cancer, with a highly aggressive phenotype and poor prognosis. RNA binding proteins (RBPs) play crucial roles in post-transcriptional gene regulation have been implicated tumorigenesis. RBPs potential to become new therapeutic target for ccRCC. In this study, we screened validated that insulin-like growth factor 2 mRNA protein (IGF2BP2) as an RBP, was down-regulated ccRCC tissues lines. Functionally, verified IGF2BP2...