A5057035824- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Aortic Disease and Treatment Approaches
- Transplantation: Methods and Outcomes
- Cardiac Valve Diseases and Treatments
- Tracheal and airway disorders
- Cardiovascular and Diving-Related Complications
- Vascular anomalies and interventions
- Cardiovascular Effects of Exercise
- Congenital Diaphragmatic Hernia Studies
- Coronary Artery Anomalies
- Infective Endocarditis Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Cardiomyopathy and Myosin Studies
- Pericarditis and Cardiac Tamponade
- Cardiac pacing and defibrillation studies
Newcastle upon Tyne Hospitals NHS Foundation Trust
2018-2023
Freeman Hospital
2015-2023
Newcastle University
2022-2023
Evelina London Children's Healthcare
2017-2018
University of Toronto
2017
Guy's and St Thomas' NHS Foundation Trust
2017
Adults with failing Fontan circulation (FFC) represent a heterogeneous, high-risk group for cardiac transplantation poor reported outcomes. We studied the impact of mode failure (preserved versus impaired systolic ventricular function) and end-organ dysfunction on early survival in adults undergoing FFC.A single-centre, retrospective study 26 (≥16 years) FFC between 1990 2015. Patients were classified by presence or absence preserved function (PVF). End-organ was assessed serum markers,...
Objectives Mortality associated with the modified Blalock–Taussig shunt (MBTS) remains high despite advanced perioperative management. This study was formulated to provide data on (1) current indications, (2) outcomes, and (3) factors affecting mortality morbidity. Design A retrospective single center chart review identified 95 children (excluding hypoplastic left heart lesions) requiring a MBTS. major morbidity were analyzed using Kaplan Meier method risk factor analysis Cox's proportional...
Abstract Background and Aims Transcatheter pulmonary valve implantation (TPVI) is indicated to treat right-ventricular outflow tract (RVOT) dysfunction related congenital heart disease (CHD). Outcomes of TPVI with the SAPIEN 3 that are insufficiently documented were investigated in EUROPULMS3 registry 3-TPVI. Methods Patient-related, procedural, follow-up outcome data retrospectively assessed this observational cohort from 35 centres 15 countries. Results Data for 840 consecutive patients...
Objectives Adults with congenital heart disease (ACHD) are a growing group end-stage failure. We aim to describe the outcomes of ACHD patients undergoing assessment for orthotopic transplant (OHT). Methods Case notes consecutive (>16 years) assessed OHT between 2000 and 2016 at our centre were reviewed. Decision outcome reported as 2017. Data analysed in three groups: systemic left ventricle (LV), right (RV) single (SV). Results 196 (31.8 years, 27% LV, 29% RV, 44% SV). 89 (45%) listed 67...
Objectives We set out to determine the characteristics and outcomes of symptomatic infants with tetralogy Fallot who due insufficient pulmonary blood flow required transcatheter or surgical intervention in early infancy. Methods Five centers United Kingdom contributed data for born underwent an initial procedure between January 2015 2022. The studied group were requiring palliative reparative at less than three months age. primary outcome was survival one year; secondary periprocedural...
Background: Hypoplastic left heart syndrome (HLHS) with either intact atrial septum (IS) or highly restrictive interatrial communication (HRIC) is associated poor survival. Immediate postpartum access to cardiac therapy and timely decompression (LAD) are paramount a successful outcome. We describe herein our evolving approach LAD report interstage longer-term results. Methods: retrospectively identified neonates HLHS IS/HRIC requiring between 2005 2019. All babies had prenatal/postnatal...
Our goal was to present 2 decades of our experience with the Ross procedure and its sequential modifications, adopted since 2010, improve reoperation rate.We performed a single-centre, retrospective review database information medical notes about implantation technique: freestanding root. We compared era 1 (1997-2009) (2010-2019).Between 1997 2019, total 214 procedures were (71% men, median age 24 years) [interquartile range (IQR) 15-38]. Of these, 87% had various forms congenital-dysplastic...
Ventricular assist device (VAD) for systemic right ventricular (RV) failure patients post-atrial switch, transposition of the great arteries (TGA), and those with congenitally corrected TGA has proven useful to reduce transpulmonary gradient bridge-to-transplantation. The purpose this study is describe our experience VAD in RV move towards concomitant tricuspid valve replacement (TVR).This a single-centre retrospective consecutive adult receiving HeartWare between 2010 2019. From 2017, TVR...
Objectives To describe a novel strategy for the management of infants with hypoplastic left heart syndrome (HLHS) and intact atrial septum. Antenatally diagnosed are delivered in cardiac theatre immediate decompression (LAD) using hybrid transatrial stent insertion (HTSI) via sternotomy is carried out. Background HLHS septum condition incompatible life following placental separation. Despite number reported strategies survival these remains much worse than those born an adequate...
Contemporarily modified Ross procedure continues to deliver excellent outcomes and remains part of the treatment strategy for aortic valve disease in young adult population. The aim this study was assess whether carried out as a second or subsequent intervention carries similar risk long-term benefit, when compared first-time replacement.A total 158 patients aged 16-60 years from single congenital cardiac centre between 1997 2020 were included. sample split into 2 subgroups, based on history...
Cardiomyopathy may have a variety of causes and lead to significant morbidity. Often, there is no “perfect” treatment. New investigative techniques add insight but retain the possibility uncertainty. The distinction between restrictive cardiomyopathy pericardial constriction be challenging, particularly when considering incidence these entities. This significantly impact patient management this becoming increasingly important in context donor organ austerity. We present case 17-year-old male...
Abstract Aims Patients with systemic right ventricles are at high risk of sudden cardiac death. Arrhythmia is a significant factor. Routine Holter monitoring opportunistic poor adherence. The aim this study was to determine if continuous rhythm an implantable loop recorder (ILR) could allow early detection clinically important arrhythmias. Methods and results Implantable implantation offered patients atrial switch repair for transposition the great arteries. Recordings were made symptoms or,...
Background A 9-year-old boy with Berlin Heart biventricular assist device for diagnosis of dilated cardiomyopathy developed progressive reduction in left ventricular device(VAD) emptying and evidence low cardiac output despite alterations to the settings. Computed tomography revealed that Dacron graft attaching systemic cannula ascending aorta was stenosed. Method & Result minimally invasive approach novel circuit modification used achieve antegrade stenting stenosed graft. Conclusion This...
<h3>Purpose</h3> Most reports on the outcome of children who present with heart failure are from an era when ventricular assist devices (VAD) were not available. This study provides data for modern where prolonged circulatory support can be considered all ages. <h3>Methods</h3> Data presented 2010–2015, a first diagnosis failure, excluding those structural disease, was retrieved. <h3>Results</h3> The median age at presentation, in 100 children, 18 months. Overall, hospital mortality 15%, 50%...