A5103212106- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Functional Brain Connectivity Studies
- Neurobiology of Language and Bilingualism
- Neurological Disorders and Treatments
- Developmental and Educational Neuropsychology
- Aging, Health, and Disability
- Cognitive Abilities and Testing
- Emotional Intelligence and Performance
- Cardiovascular Health and Risk Factors
- Health Policy Implementation Science
- Health, Environment, Cognitive Aging
- Hemispheric Asymmetry in Neuroscience
- Intensive Care Unit Cognitive Disorders
- Educational and Psychological Assessments
- Emotions and Moral Behavior
- Memory Processes and Influences
- Neuroscience, Education and Cognitive Function
- Blood Pressure and Hypertension Studies
- Children's Physical and Motor Development
- Interprofessional Education and Collaboration
- Cardiac Health and Mental Health
- Autism Spectrum Disorder Research
- Genetics and Neurodevelopmental Disorders
- Cholinesterase and Neurodegenerative Diseases
Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia
2015-2025
Instituto de Neurología Cognitiva
2013-2024
Measures of social cognition have now become central in neuropsychology, being essential for early and differential diagnoses, follow-up, rehabilitation a wide range conditions. With the scientific world becoming increasingly interconnected, international neuropsychological medical collaborations are burgeoning to tackle global challenges that mental health These initiatives commonly merge data across diversity populations countries, while ignoring their specificity.
Abstract INTRODUCTION Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm‐FINGERS) is the first non‐pharmacological multicenter randomized clinical trial (RCT) prevent cognitive impairment in America (LA). Our aim present study design and discuss strategies used multicultural harmonization. METHODS This 1‐year RCT (working on a extension) investigates feasibility of multi‐domain lifestyle intervention LA efficacy intervention, primarily function. An...
Purpose To describe results of the Amyloid, Tau, Neurodegeneration (ATN) research framework classification in Argentine-Alzheimer's Disease Neuroimaging Initiative (arg-ADNI) cohort. Methods Twenty-three patients with mild cognitive impairment (MCI), 12 dementia Alzheimer's type (DAT), and 14 normal controls were studied following ADNI2 protocol. Patients categorized according to presence or absence biomarkers for amyloid beta (Aβ; A: positron emission tomography [PET] scan cerebrospinal...
Abstract Harmonized neuropsychological assessment for neurocognitive disorders (NCDs) is an urgent priority in clinics. Neuropsychology assessments NCDs seldom include tests exploring social cognitive skills. In 2022, we launched the SIGNATURE initiative to optimize socio‐cognitive NCDs. Here, report findings from first phase, including consortium creation and evaluation of state art memory We developed ad hoc online survey explore practices measures, relevance, obstacles preventing use...
Most studies examining episodic memory in Alzheimer disease (AD) have focused on patients' impaired ability to remember information. This approach provides only a partial picture of deficits since other factors involved are not considered.To evaluate the recognition performance by using yes/no procedure examine effect discriminability and response bias measures amnestic mild cognitive impairment (a-MCI), AD dementia, normal-aging subjects.We included 43 controls 45 a-MCI 51 dementia...
Limb apraxia comprises many different and common disorders, which are largely unrecognized essentially because there is no easy-to-use screening test sensitive enough to identify all types of limb praxis deficits.We evaluated 70 right-handed patients with due a single focal lesion the left hemisphere 40 normal controls, using new test. The covered 12 items including: intransitive gestures, transitive gestures elicited under verbal, visual, tactile modalities, imitation meaningful meaningless...
The purpose of this study was to investigate the relationship between cognitive reserve and concentration Aβ1-42 in cerebrospinal fluid (CSF) patients with mild impairment, those Alzheimer's disease, control subjects.Thirty-three participants from Argentina-Alzheimer's Disease Neuroimaging Initiative database completed a battery, Cognitive Reserve Questionnaire (CRQ), an Argentinian accentuation reading test (TAP-BA) as measure premorbid intelligence, underwent lumbar puncture for CSF...
ABSTRACT The Argentina-Alzheimer's disease neuroimaging initiative (Arg-ADNI) study is a longitudinal prospective cohort of 50 participants at single institution in Buenos Aires, Argentina. Longitudinal assessments on neuropsychological test battery were performed 15 controls, 24 mild cognitive impairment (MCI) patients and 12 Alzheimer's (AD) dementia patients. In our population, there was high prevalence positive AD biomarkers the group, 92.3% (12/13); low normal 20%; almost half (48%)...
Increased life expectancy and exponential growth of adults suffering from Alzheimer's disease (AD) worldwide, has led to biomarkers incorporation for diagnosis in early stages. Use neuropsychological testing remains limited. This study aimed identify which tests best indicated underlying AD pathophysiology.One hundred forty-one patients with MCI (Mild Cognitive Impairment) were studied. A test battery based on the Uniform Data Set (UDS) Disease Centers program National Institute Aging (NIA)...
Abstract Background The 2021 WHO report highlights the importance of global planning for dementia. Initiatives that unite and support young leaders stakeholders from diverse backgrounds in dementia care & research are crucial. G8 Summit on Dementia 2013 led to creation World Council Young Leaders (WYLD) network, which connects professionals work together finding solutions challenges. With emergence new leadership structure January 2024 we aim present our 2024‐2029 roadmap. Method We...
Abstract Background Dementia represents a significant health challenge, with evidence suggesting that it can be potentially delayed or prevented through non‐pharmacological interventions. There are different types of interventions for Mild Cognitive Impairment (MCI). The Aging Well Interaction and Scientific Education (AgeWISE) Program is notable cognitive intervention designed to educate both individuals experiencing normal aging those age‐related diseases. It offers strategies managing...
OBJECTIVE: To describe related factors to conversion from CDR 0,5 1 in the ADNI-Arg population BACKGROUND: Alzheimer disease (AD) represents most frequent cause of dementia worldwide, knowledge about this disorder have increased dramatically during last decade. ADNI is one projects that contributed achievement; using a multimodal approach including neuropsychological assessment, Magnetic Resonance Imaging (MRI) and biomarkers such as PET Scan, Cerebrospinal Fluid (CSF): Amyloid protein...
The Argentina- Alzheimer's Disease Neuroimaging Initiative (Arg-ADNI) study is a longitudinal prospective cohort of 60 participants at single institution from Buenos Aires, Argentina. Arg-ADNI the first worldwide ADNI center in Latin America and Hispanic community-dwelling subjects worldwide. Baseline assessments have been done on 15 normal controls, 28 mild cognitive impairment (MCI) 13 AD dementia subjects, with 4 lost to follow-up. For Arg-ADNI, magnetic resonance imaging (MRI),...
It is important for elderly patients with cognitive impairment to assess the impact that memory loss has on functional capacity of everyday activities. Performance these activities directly related independent living and need care. Systematic assessment appropriate scales thus an clinical research issue. The Everyday Cognition (ECog) scale a relatively new informant subjective-rated measure instrumental daily function. objective this study was determine validity internal consistency...
In elderly patients with cognitive impairment is it important for diagnostic and clinical issues to assess objectively the functional activities of every day. present study, we aimed explore existence an association between status based on assessment informant- ECog score presence brain amyloid, using PiB-PET imaging, from Argentina-ADNI cohort. All participants were enrolled in study. Fifty subjects included analysis, 13 whom have a current diagnosis mild Alzheimer's disease (AD) dementia,...
Abstract Background In recent years, there has been an increase in the number of case reports families with autosomal dominant Alzheimer’s disease (ADAD) Latin America (LA). Nevertheless, little is known about clinical phenotypes and demographic characteristics mutations each country. Past literature proved that variants LA have different unique than those reported Asia, North America, Europe. Clinical heterogeneity ADAD supports need to study phenotypes, especially preclinical stages,...
The aim of the present study is to report conversion rate, time and determinate which basal assessment measures could predict dementia in a 60 month longitudinal follow up ADNI-Arg cohort. Fifty-six subjects from cohort fulfill criteria for Healthy Control (HC) (n=15) Mild Cognitive Impairment (MCI), (n=28) or Dementia Alzheimer Type (DTA) (n=13). Conversion was defined as change CDR (global score). A event analysis performed order determine median groups differences. In subanalysis on MCI...