Hongli Yu

ORCID: 0000-0003-4375-0496
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Research Areas
  • Plant-based Medicinal Research
  • Bioactive Natural Diterpenoids Research
  • Phytochemistry and Biological Activities
  • Traditional Chinese Medicine Analysis
  • Natural product bioactivities and synthesis
  • Flavonoids in Medical Research
  • Phytochemistry and Bioactive Compounds
  • Nanoplatforms for cancer theranostics
  • Heme Oxygenase-1 and Carbon Monoxide
  • Mast cells and histamine
  • Ginger and Zingiberaceae research
  • Inflammasome and immune disorders
  • Characterization and Applications of Magnetic Nanoparticles
  • Angiogenesis and VEGF in Cancer
  • Metal-Organic Frameworks: Synthesis and Applications
  • Peroxisome Proliferator-Activated Receptors
  • Phytochemical and Pharmacological Studies
  • Cancer, Lipids, and Metabolism
  • Cancer, Hypoxia, and Metabolism
  • Immune Response and Inflammation
  • Advanced Photocatalysis Techniques
  • Berberine and alkaloids research
  • Drug Transport and Resistance Mechanisms
  • Cancer Treatment and Pharmacology
  • MicroRNA in disease regulation

Nanjing University of Chinese Medicine
2015-2025

University of Science and Technology Beijing
2025

Materials Science & Engineering
2025

Shenyang University of Technology
2024

Qingdao University
2020-2024

Fourth Affiliated Hospital of Guangxi Medical University
2021

Weifang Medical University
2018-2020

Fuzhou University
2019

Tianjin First Center Hospital
2019

Tianjin Medical University
2019

The purpose of the research was to determine effect nano-hydroxyapatite concentrations on initial enamel lesions under dynamic pH-cycling conditions. Initial were prepared in bovine with an acidic buffer. NaF (positive control), deionized water (negative control) and four different (1%, 5%, 10% 15% wt%) selected as treatment agents. Surface microhardness (SMH) measurements performed before/after demineralization after 3, 6, 9 12 days application, percentage surface recovery (%SMHR)...

10.1088/1748-6041/4/3/034104 article EN Biomedical Materials 2009-06-01

The Traditional Chinese Medicine herbs Pollen Typhae and Carbonisatus have been used as a hemostatic medicine promoting blood clotting for thousands of years. In this study, reliable, highly sensitive method based on LC-MS/MS has developed differentiation the heating products total flavonoids in (FPT-N). Twenty three peaks were detected 18 structurally identified by comparing retention times, high resolution mass spectrometry data, fragment ions with those reference substances and/or...

10.3390/molecules201018352 article EN cc-by Molecules 2015-10-08

Background . The neuronal injury and cognitive dysfunction after liver transplantation have severe effects on the prognosis life quality of patients. Accumulating evidence suggests that both exosomes pyroptosis could participate in hepatic ischemia-reperfusion (HIRI) play key roles death. However, link between HIRI awaits further investigation. Methods. After establishing rat models, we primarily studied role hippocampal cortical neuron through detecting NOD-like receptor protein 3 (NLRP3),...

10.1155/2019/3753485 article EN Oxidative Medicine and Cellular Longevity 2019-11-13

Nasopharyngeal carcinoma (NPC) is a common epithelial malignancy that occurs in the nasopharynx and it one of high incidences malignant tumors China. As previous reports, berberine hydrochloride (BH) possesses repressive effect on proliferation various cancer types. But application BH was hampered for long time due to its hydrophobic properties, along with poor stability bioavailability. In this study, folate acid modified chitosan nanoparticles loaded (BH/FA-CTS NPs) were prepared by ionic...

10.1166/jbn.2018.2596 article EN Journal of Biomedical Nanotechnology 2018-06-15

Organic–inorganic metal halides (OIMHs) have attracted considerable attention owing to their unique optoelectronic properties. Here, we successfully synthesized five lead, manganese and copper containing OIMHs based on 4-aminodiphenylmethane (C13H13N) 4,4′-methylenedianiline (C13H14N2). Among them, (C13H14N)2PbCl4 (C13H14N)2PbBr4, both exhibiting two-dimensional frameworks, crystallize into the Pmm2 P21/c space groups, respectively, present optical band gaps of approximately 3.6 3.0 eV....

10.1021/acs.inorgchem.5c00163 article EN Inorganic Chemistry 2025-02-26

The excellent optoelectronic properties of layered halide perovskites make them ideal for devices such as solar cells, light-emitting diodes, and photodetectors. In this study, we report five two-dimensional (2D) perovskites: (C6H14N2)PbBr4, (C8H18N2)PbBr4·H2O, (C6H14N2)PbI4, 1-(C8H18N2)PbI4, 2-(C8H18N2)PbI4, (C6H14N2 = N-Ethylpiperazine, C8H18N2 1-Butylpiperazine). optical band gaps these compounds range from 2.63 to 3.35 eV. (C6H14N2)PbBr4 exhibits broad orange emission with a peak at 624...

10.1021/acs.inorgchem.5c01472 article EN Inorganic Chemistry 2025-05-05

Organic-inorganic metal halides (OIMHs) are widely recognized for their varied structures, tunable bandgaps, and outstanding efficiency in optoelectronic applications. Meanwhile, temperature-dependent luminescent lifetime supports advanced functionalities such as temperature...

10.1039/d5tc00705d article EN Journal of Materials Chemistry C 2025-01-01

Inhibition of autophagy increases the sensitivity tumor cells to radiotherapy and chemotherapy improves therapeutic effect on tumors. Recently, photodynamic therapy (PDT) combined with has been proven further improve efficiency cancer treatment. As such, combining inhibition PDT may represent a potentially effective new strategy for However, currently widely studied inhibitors inevitably produce various toxic side effects due their inherent pharmacological activity. To overcome this...

10.1021/acs.molpharmaceut.4c00203 article EN Molecular Pharmaceutics 2024-08-06

Flos Sophorae and its processed product have been clinically used to treat hemorrhage. In this study, the total ion chromatographic fingerprints of heating products flavonoids in were established by high‐performance liquid chromatography with tandem mass spectrometry hemostatic activities studied screening tests vivo. The spectrum–effect relationships between investigated using canonical correlation analysis trace peaks responsible for effects. predicted active isolated column their...

10.1002/jssc.201500100 article EN Journal of Separation Science 2015-03-12

The electronic properties and metal ion (Li, Na, Mg) storage capabilities of the two-dimensional Ti<sub>3</sub>N<sub>2</sub> monolayer its Ti<sub>3</sub>N<sub>2</sub>X<sub>2</sub> derivatives (X = O, F, OH) as anode materials in rechargeable batteries are investigated by DFT computations.

10.1039/c9ra07670k article EN cc-by-nc RSC Advances 2019-01-01

A new casbane diterpenoid, referred to as pekinenin G, together with one cembrane diterpene and four known diterpenoids were isolated from the roots of Euphorbia pekinensis. Their structures elucidated on basis spectroscopic studies comparison related compounds. The six compounds showed different cytotoxic activities against human cancer cell lines.

10.1080/14786419.2015.1027704 article EN Natural Product Research 2015-04-07

Platycladi cacumen and its processed product have been utilized as a Chinese medicine to treat hemorrhages. In this study, the base peak chromatogram fingerprints of heating products total flavonoids in were established by high performance liquid chromatography coupled with mass spectroscopy/mass spectroscopy (HPLC-MS/MS), hemostatic activities studied screening tests vivo. The spectrum-effect relationships between analyzed using canonical correlation analysis trace peaks responsible for...

10.3390/molecules200916970 article EN cc-by Molecules 2015-09-17
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