Yi Chen

ORCID: 0000-0003-4426-406X
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About
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Research Areas
  • Microfluidic and Capillary Electrophoresis Applications
  • Analytical Chemistry and Chromatography
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Mass Spectrometry Techniques and Applications
  • Advanced biosensing and bioanalysis techniques
  • Microfluidic and Bio-sensing Technologies
  • Plasmonic and Surface Plasmon Research
  • Monoclonal and Polyclonal Antibodies Research
  • Biosensors and Analytical Detection
  • Photonic Crystals and Applications
  • Analytical chemistry methods development
  • Advanced Polymer Synthesis and Characterization
  • Soil Carbon and Nitrogen Dynamics
  • Photonic and Optical Devices
  • Nanopore and Nanochannel Transport Studies
  • Diatoms and Algae Research
  • Surface Modification and Superhydrophobicity
  • Biocrusts and Microbial Ecology
  • Agriculture and Biological Studies
  • Microbial Natural Products and Biosynthesis
  • Pickering emulsions and particle stabilization
  • Algal biology and biofuel production
  • Soil and Environmental Studies
  • Chemical Synthesis and Analysis
  • Nanoparticle-Based Drug Delivery

Chinese Academy of Sciences
2016-2025

Beijing National Laboratory for Molecular Sciences
2012-2025

University of Chinese Academy of Sciences
2014-2025

Huaiyin Institute of Technology
2020-2024

Lanzhou Institute of Chemical Physics
2020-2022

Institute of Hydrobiology
2020-2022

Institute of Geographic Sciences and Natural Resources Research
2020-2022

South China Sea Institute Of Oceanology
2022

Institute of Oceanology
2022

Changchun Institute of Optics, Fine Mechanics and Physics
2021

Multilayer films of shortened multiwalled carbon nanotubes (MWNTs) are homogeneously and stably assembled on glassy electrodes with the layer-by-layer (LBL) method, based electrostatic interaction positively charged poly(diallyldimethylammonium chloride) negatively MWNTs. The film assembly electrochemical property as well electrocatalytic activity toward O2 reduction MWNT multilayer studied. Scanning electron microscopy, quartz crystal microbalance technique,...

10.1021/la048923l article EN Langmuir 2004-09-01

Abstract Smallholder farmers in sub‐Saharan Africa (SSA) currently grow rainfed maize with limited inputs including fertilizer. Climate change may exacerbate current production constraints. Crop models can help quantify the potential impact of climate on yields, but a comprehensive multimodel assessment simulation accuracy and uncertainty these low‐input systems is lacking. We evaluated varying [CO 2 ], temperature rainfall conditions yield, for different nitrogen (N) (0, 80, 160 kg N/ha)...

10.1111/gcb.15261 article EN Global Change Biology 2020-07-06

Polydopamine (PDA)-based surface modification has been used in a variety of fields. However, vague impression on the stability PDA still exists due to lack systematic studies. To ascertain issue and make better use this method, technique plasmon resonance imaging (SPRi) was exploited study coated gold surface. The results showed that PDA-coating largely dependent pH aqueous solutions, giving detachment ratios up 66% 80% at 1.0 14.0, respectively. increasing ionic strength solutions could...

10.1021/acs.langmuir.7b03143 article EN Langmuir 2018-03-05

Due to its strong ultraviolet absorption, high salt tolerance, and little interference in the low molecular weight region, N-(1-naphthyl) ethylenediamine dihydrochloride (NEDC) has been applied as a matrix measure level of glucose rat brain microdialysates by matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) combination with vivo microdialysis. By monitoring ion signals (glucose + Cl)− spectra, we achieved detection limit ∼10 μM for 126 mM NaCl, which is typical...

10.1021/ac202438a article EN Analytical Chemistry 2011-11-23

The superparamagnetic surface molecularly imprinted Fe3O4@MIP nanoparticles for bisphenol A (BPA) were prepared via initiated atom transfer radical polymerization (si-ATRP). Fe3O4 core was compactly encapsulated with a polychloromethylstyrene (PCMS) layer viamini-emulsion polymerization. exhibited property saturation magnetization of 25.2 emu g−1. BPA revealed specific selectivity and high affinity to the template over structural analogues. Moreover, surface-imprinted MIP showed good site...

10.1039/c1jm10227c article EN Journal of Materials Chemistry 2011-01-01

Chromochloris zofingiensis has obtained particular interest as a promising candidate for natural astaxanthin production. In this study, we established two-stage heterotrophic cultivation process, by using which both the growth of C. and accumulation are substantially enhanced. Specifically, ultrahigh biomass concentration 221.3 g L-1 was achieved under optimum culture conditions in 7.5 L fermenter during 12 days. When scaled-up 500 fermentor, yield reached 182.3 9 days, while content 0.068%...

10.3389/fbioe.2022.834230 article EN cc-by Frontiers in Bioengineering and Biotechnology 2022-02-24

A series of glycidyl methacrylate-based polymer monoliths, including spherical walled structures, sub-micron skeletons, and lamellar morphologies, are reproducibly prepared by high internal phase emulsions in combination with block copolymer chemistry. The morphologies could be manipulated over a wide range only altering the typical tri-block (Pluronic F127) concentration. ability Pluronic F127 to direct supramolecular self-assembly is main reason for rich behavior exhibited such as micellar...

10.1039/b816712e article EN Journal of Materials Chemistry 2008-12-18

In this study, oligo(ethylene glycol) (OEG)-based thermoresponsive molecularly imprinted polymers (MIPs) for lysozyme on the surface of magnetic nanoparticles were synthesized. Thermoresponsive monomer 2-(2-methoxyethoxy)ethyl methacrylate, chelate N-(4-vinyl)-benzyl iminodiacetic acid, and acidic methacrylic acid selected as ingredients preparing MIP layer. The behavior novel was evaluated by dynamic light scattering swelling ratios measurements. Interestingly, in analysis lysozyme,...

10.1021/am505427j article EN ACS Applied Materials & Interfaces 2014-09-08

Recent years have witnessed the rapid progress in deep learning (DP), which also brings their potential weaknesses to spotlights of security and machine studies. With important discoveries made by adversarial research, surprisingly little attention, however, has been paid real-world techniques deployed cybercriminal evade image-based detection. Unlike examples that induce misclassification using nearly imperceivable perturbation, images tend be less optimal yet equally effective. As a first...

10.1109/sp.2019.00032 article EN 2022 IEEE Symposium on Security and Privacy (SP) 2019-05-01

In this study, a novel fluorescent and temperature responsive block copolymer has been designed synthesized by reversible addition–fragmentation chain transfer (RAFT) polymerization method in terms of the strategy that N-isopropylacrylamide (NIPAm), maleic anhydride (MAn) 7-amino-4-methylcoumarin (AMC) act as unit, hydrophilic unit respectively. The successfully was characterized gel permeation chromatography (GPC) nuclear magnetic resonance (1H NMR) spectroscopy. Meanwhile, self-aggregation...

10.1039/c2jm31093g article EN Journal of Materials Chemistry 2012-01-01

The stability of slippery liquid-infused porous surfaces (SLIPSs) is great significance in long-term applications.

10.1039/d0ta08717c article EN Journal of Materials Chemistry A 2020-01-01

We have found a new way, metal-organic coordination gel template method, to generate polymer monoliths with an essentially macropore size, in which the pores are organized spontaneously into continuous networks; furthermore, resulting macroporous potential applications high-throughput and high-efficiency separation of proteins.

10.1039/b709865k article EN Chemical Communications 2007-01-01

A novel integrated continuous-flow microfluidic system was designed and fabricated for solid phase peptide synthesis (SPPS) using conventional reactants. The composed of a glass-based radial reaction chip, diffluent amino acid feeding reservoirs reagent pathways. tri-row cofferdam-fence structure supports trapping. Highly cross-linked, porous high-loading 4-(hydroxymethyl)phenoxymethyl polystyrene (HMP) beads were prepared SPPS. transfer losses, hazardous handling time-consuming processes in...

10.1039/c0lc00542h article EN Lab on a Chip 2011-01-01

In this perspective article, several internationally recognized experts, members of the editorial team journal, discuss a selection current hot topics identified in Food Science and Foodomics. The are comprised main areas Foodomics, namely, food safety, authenticity, processing, bioactivity. Logically, discussed involve more than one mentioned areas. Regarding use analytical nanotechnology, nanometrology, nano-chromatography; determination organic contaminants based on MS NMR; impact...

10.37349/eff.2024.00060 article EN cc-by 2024-11-28

Ligand binding to membrane proteins initiates numerous therapeutic processes. Surface plasmon resonance (SPR), a popular method for analyzing molecular interactions, has emerged as promising tool in situ determination of protein kinetics owing its label-free detection, high surface sensitivity, and resistance intracellular interference. However, the excitation SPR relies on noble metal films, typically gold, which are biologically incompatible can cause fluorescence quenching. Here we...

10.1021/acs.analchem.4c05510 article EN Analytical Chemistry 2025-01-27

A chiral capillary electrophoretic method with nearly full p H window was explored for the separation and determination of dl ‐penicillamine. facile one‐pot labeling technique coupled in introduction chromophore charge groups onto analytes to facilitate electromigration sensitive detection. By using simply a cost‐effective neutral β‐cyclodextrin as selector, baseline ‐penicillamine achieved from 2.0 over 10. Quantification standard d ‐ l ‐penicillamines demonstrated by taking 4.5, 7.4, 9.7...

10.1002/elps.201200046 article EN Electrophoresis 2012-07-01

The study of enzyme immobilization using an extracorporeal shunt system is essential to eliminate the side effects L-asparaginase (L-Asnase; including hepatic toxicity, allergic reaction, pancreatitis, central nervous toxicity and decreased synthesis blood clotting factors) when it was applied as anticancer drug given directly patients by injection. Thus, novel monolith coating enzymatic reactors were provided in this assay a microchip electrophoresis–laser induced fluorescence (MCE–LIF)...

10.1039/c1an15067g article EN The Analyst 2011-01-01
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