A5073167082- Forensic and Genetic Research
- Environmental DNA in Biodiversity Studies
- Identification and Quantification in Food
- HIV Research and Treatment
- Primate Behavior and Ecology
- Blood groups and transfusion
- Genomics and Phylogenetic Studies
- Genetic and phenotypic traits in livestock
- Genomics and Chromatin Dynamics
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genetic Associations and Epidemiology
- Herpesvirus Infections and Treatments
- Amphibian and Reptile Biology
- Erythrocyte Function and Pathophysiology
- Wildlife Ecology and Conservation
- Gene expression and cancer classification
- Single-cell and spatial transcriptomics
- Pleistocene-Era Hominins and Archaeology
- Animal Behavior and Reproduction
- Parvovirus B19 Infection Studies
- Genetic Mapping and Diversity in Plants and Animals
- Human-Animal Interaction Studies
- Genetic diversity and population structure
- Animal Nutrition and Physiology
- Archaeology and ancient environmental studies
Arizona State University
2015-2025
University of California, Davis
2009-2023
Rhesus macaques ( Macaca mulatta ) are the most widely used nonhuman primate in biomedical research, have largest natural geographic distribution of any primate, and been focus much evolutionary behavioral investigation. Consequently, rhesus one thoroughly studied species. However, little is known about genome-wide genetic variation this A detailed understanding extant genomic among has implications for use species as a model studies human health disease, well population genomics....
Genomics research has uncovered recurrent hybridization between hominin species, yet its morphological impact remains understudied. Non-human primate suggested a signature of hybrid ancestry, which could be used to identify hybrids in the fossil record. This pattern may include extreme size, heightened variation, and markers developmental instability, but factors affecting these characteristics are poorly understood. Studies non-mammalian taxa suggest that morphology is more likely...
Abstract Wildlife‐related crimes are the second most prevalent lawbreaking offense globally. This illicit trade encompasses hunting, breeding and trafficking. Besides diminishing many species their habitats ecosystems, hindering economic development of local communities that depend on them, undermining rule law financing terrorism, various cross‐species transmissions (zoonoses) pathogens, including COVID‐19, can be attributed to wildlife crimes. Wildlife forensics applies interdisciplinary...
Abstract The National Primate Research Centers (NPRCs) established Working Groups (WGs) for developing resources and mechanisms to facilitate collaborations among non‐human primate (NHP) researchers. Here we report the progress of Genome Banking Genetics Genomics WGs in advance exchange, analysis comparison NHP genetic genomic data across NPRCs. WG has a DNA bank comprising 1250 samples from unrelated animals family trios 10 species housed within NPRC system. is SNP arrays that will provide...
Rhesus macaques are the most common nonhuman primate model organism used in biomedical research. Their increasingly frequent use as subjects studies involving transplantation requires that blood and other tissue antigens of donors recipients be compatible. We report here an easy rapid multiplex polymerase chain reaction (PCR) to determine ABO group phenotypes rhesus can performed with only small amounts DNA. phenotyped 78 individuals found this species exhibit A, B AB frequencies vary by...
Summary Almost half of all US households own a dog ( Canis familiaris ). Though these household pets can attack humans and other animals, they are also frequently victims cruelty, neglect theft. In human‐oriented investigations, the tendency domestic dogs to leave behind physical traces (such as hair) serve valuable links between crime scenes suspects/victims. This demonstrated utility canine biological evidence has created demand for genotyping marker sets forensic genetic testing. Through...
Abstract Macaques are commonly used in biomedical research as animal models of human disease. The ABO phenotype donors and recipients plays an important role the success transplantation stem cell both macaque tissue. Traditional serological methods for phenotyping can be time consuming, provide ambiguous results and/or require tissue that is unavailable or unsuitable. We developed a novel method to detect A , B AB phenotypes macaques using real‐time quantitative polymerase chain reaction....
Abstract Background Conservation of single nucleotide polymorphisms ( SNP s) between human and other primates (i.e., heterospecific in candidate genes can be used to assess the utility those organisms as models for biomedical research. Methods A total 59,691 s 22 rhesus macaques 20 humans were analyzed trait associations 4207 biallelic both taxa compared genetic variation. Results Variation comparisons at showed that more genetically diverse than with observed expected heterozygosities 0.337...
A much larger sample (N = 2369) was used to evaluate a previously reported distribution of the A, AB and B blood group phenotypes in rhesus cynomolgus macaques from six different regional populations. These samples, acquired 15 breeding research facilities United States, were analyzed using real-time quantitative polymerase chain reaction (qPCR) assay that targets single nucleotide polymorphisms (SNPs) responsible for macaque phenotypes. The frequency distributions two species differ...
Abstract Pedigree metrics are essential for investigating colony genetic structure. The structure of a closed Callicebus cupreus was examined using multigenerational pedigrees. Inbreeding low, but drift caused the loss founder genome representation. Pedigrees can be used to detect representation and prevent bottlenecks allele loss.