A5016585458- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Long-Term Effects of COVID-19
- Family and Patient Care in Intensive Care Units
- Sepsis Diagnosis and Treatment
- Cardiac Structural Anomalies and Repair
- Hemodynamic Monitoring and Therapy
- COVID-19 Clinical Research Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Clostridium difficile and Clostridium perfringens research
- Cardiovascular Disease and Adiposity
- Adrenal Hormones and Disorders
- Prostate Cancer Diagnosis and Treatment
- Healthcare Systems and Public Health
- Chronic Myeloid Leukemia Treatments
- Climate Change and Health Impacts
- Thermal Regulation in Medicine
- Cardiac pacing and defibrillation studies
- Immune Response and Inflammation
- Mechanical Circulatory Support Devices
- Central Venous Catheters and Hemodialysis
- Prostate Cancer Treatment and Research
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Health and Risk Factors
- Pediatric Pain Management Techniques
Boston University
2025
University of Miami
2022-2024
Jackson Memorial Hospital
2022-2023
John H. Stroger, Jr. Hospital of Cook County
2023
Miami Transplant Institute
2023
University of Chicago Medical Center
2020-2023
University of Chicago
2021-2022
University of Cartagena
2019
Fundación Santa Fe de Bogotá
2019
Abstract Respiratory failure and mortality from COVID-19 result virus- inflammation-induced lung tissue damage. The intestinal microbiome associated metabolites are implicated in immune responses to respiratory viral infections, however their impact on progression of severe remains unclear. We prospectively enrolled 71 patients with critical illness, collected fecal specimens within 3 days medical intensive care unit admission, defined compositions by shotgun metagenomic sequencing,...
Objectives: We recently found that distinct body temperature trajectories of infected patients correlated with survival. Understanding the relationship between and host immune response to infection could allow us immunophenotype at bedside using temperature. The objective was identify whether have consistent associations specific cytokine responses in two cohorts patients. Design: Prospective observational study. Setting: Large academic medical center 2013 2019. Subjects: Two patients: 1)...
In acute respiratory distress syndrome (ARDS), dead space fraction has been independently associated with mortality. We hypothesized that early measurement of the difference between arterial and end-tidal CO2 (arterial-ET difference), a surrogate for fraction, would predict mortality in mechanically ventilated patients ARDS.We performed two separate exploratory analyses. first used publicly available databases from ALTA, EDEN, OMEGA ARDS Network trials (N = 124) as derivation cohort to test...
SUMMARY INTRODUCTION: Assessment of acute postoperative pain is mandatory for effective treatments. Pain trajectories may help professionals improve It has been suggested that uncontrolled in the immediate period generates higher intensities on following days hospital stay. OBJECTIVE: To determine relationship between during first hour and 24 hours. METHODS: Setting: a general university hospital. Study design: prospective observational, analytical study patients undergoing surgical...
Rationale: In patients who are mechanically ventilated, diaphragm thinning on ultrasound is thought to correlate with atrophy and has been associated prolonged intubation. Factors other than atrophy, however, may cause changes in thickness, which confound studies examining thickness over time. Objectives: To determine if the mode of mechanical ventilation or an interruption sedatives have immediate effects measurements adult intensive care unit ventilated. Methods: Adult receiving invasive...
RATIONALE: A high percentage of patients with Covid-19 associated acute hypoxemic respiratory failure (AHRF) receive invasive mechanical ventilation, which is a mortality. Noninvasive ventilation (NIV) offers an alternative to though its role in both de novo AHRF and pandemic viral pneumonia has been controversial. Our group previously demonstrated that NIV delivered by helmet reduces endotracheal intubation rates improves mortality distress syndrome when compared facemask randomized...
Introduction: Dasatinib is one of the first-line therapies for CML. A large pericardial effusion requiring drainage has rarely been documented among its adverse effects, and treatment still a subject study. Case Presentation: 44-year-old female with history chronic myeloid leukemia (CML) in remission on past 10 years presented to emergency complaints chest pain palpitations 3 weeks. Physical examination was remarkable muffled heart sounds tachycardia. No JVD, pulsus paradoxus, or hypotension...
RATIONALE: Survivors of critical illness are at risk for long-term physical disability and poor quality life. Changes in health care delivery, such as visitor restrictions limited availability therapy services coupled with economic hardship due to the COVID-19 pandemic may exacerbate these consequences. Methods: Patients respiratory failure requiring advanced support (endotracheal tube, noninvasive ventilation, or high-flow nasal cannula) and/or shock admitted intensive unit (ICU) were...
Despite the benefits of intra-aortic balloon pump (IABP) being a subject debate, it remains widely available and easy-to-use mechanical circulatory support device. Nonetheless, its use is not exempt from complications. Aortic dissection IABP an infrequent but deathly complication. We describe case in which early recognition condition led to control through endovascular approach. A 57-year-old male was admitted for acute decompensated heart failure requiring intravenous inotropic agents....
OBJECTIVES: To identify cytokine signature clusters in patients with septic shock. DESIGN: Prospective observational cohort study. SETTING: Single academic center the United States. PATIENTS: Adult (≥ 18 yr old) admitted to medical ICU shock requiring vasoactive medication support. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: One hundred fourteen completed measurement at time of enrollment (t 1 ) and 24 hours later 2 ). Unsupervised random forest analysis change cytokines over time,...
ASCVD/CVD in Women Polycystic Ovary Syndrome (PCOS) involves cardiometabolic abnormalities that increase women's risk of cardiovascular disease (CVD) and are thought to predisposition worse outcomes. However, the independent association PCOS with CVD outcomes after a event is still unclear. The National Inpatient Sample (NIS) Database was queried from 2011-2019 for relevant ICD-9 -10 diagnostic procedural codes. We identified patients admitted acute coronary syndrome (ACS) included those...
Introduction: Transcatheter aortic valve replacement (TAVR) is a well-recognized treatment for severe stenosis. One potentially life-threatening complication of TAVR infective endocarditis (IE). There limited contemporary data on the clinical characteristics and outcomes patients undergoing who develop in-hospital IE. Aim: Describe Methods: The National Inpatient Sample Database was queried from 2016 to 2020 relevant ICD-10 procedural diagnostic codes. Baseline adult (≥18 years) developed IE...
Introduction: Acute coronary syndrome (ACS) is one of the main causes morbidity and mortality in elderly. Women general are less likely to be referred for catheterization, percutaneous intervention, fibrinolysis. Hypothesis: We tested hypothesis that elderly females were undergo catheterization revascularization ACS as compared men. Methods: identified hospitalizations patients aged 75 years old or older admitted with a primary admitting diagnosis NSTEMI STEMI between 2016 2019 using...
Resumen Objetivo Mundialmente, el cáncer de próstata es la segunda neoplasia maligna más frecuente en hombres a nivel mundial y primera Colombia. Se determinaron las características clínico-patológicas los casos diagnosticados un hospital región caribe colombiana. Métodos realizó estudio retrospectivo Facultad Medicina Universidad Cartagena, analizaron clínicas patológicas todos pacientes con Hospital Universitario del Caribe durante años 2007 2014. Resultados documentaron 394 casos, edad...
Rationale:Patients with COVID-19 frequently develop severe respiratory disease and may require invasive mechanical ventilation. A study of primarily white patients intubated for associated failure found predictors 28-day mortality to be system compliance, age, tidal volume, arterial pH heart rate. Little is known about the outcomes minority populations pneumonia. Therefore, we present an analysis in a group African American failure. Methods:All adult admitted University Chicago intensive...
RationaleThe novel coronavirus, COVID-19, can cause critical illness in up to 5% of infected patients. Although the sequelae surviving are known, limited data exist regarding psychological and cognitive outcomes specifically survivors COVID-19. Given social isolation, scarcity multidisciplinary staff, socio-economic impact pandemic, understanding due COVID-19 is utmost importance. MethodsA prospective observational cohort study at an academic medical center enrolled critically ill patients...