A5070372961- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Valve Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Health and Risk Factors
- Blood Pressure and Hypertension Studies
- Cardiac tumors and thrombi
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular Syncope and Autonomic Disorders
- Heme Oxygenase-1 and Carbon Monoxide
- Plasma Applications and Diagnostics
- Cardiovascular Effects of Exercise
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Ocular and Laser Science Research
- Patient-Provider Communication in Healthcare
- Myasthenia Gravis and Thymoma
- Names, Identity, and Discrimination Research
- Cardiac and Coronary Surgery Techniques
- IgG4-Related and Inflammatory Diseases
- Esophageal and GI Pathology
- Hematological disorders and diagnostics
- Sex and Gender in Healthcare
Boston University
2022-2025
Boston Medical Center
2021-2025
University Medical Center
2024
Hadassah Medical Center
2016-2022
Beth Israel Deaconess Medical Center
2019-2021
Harvard University
2019-2020
Sheba Medical Center
2020
Pulsed field ablation (PFA) is a nonthermal energy with potential safety advantages over radiofrequency ablation. This study investigated novel PFA system-a circular multielectrode catheter (PFA lasso) and multichannel generator designed to work Carto 3 mapping system.A 7.5F bidirectional 10 electrodes variable expansion was for (biphasic, 1800 Volts). included total of 16 swine used investigate the following experimental aims: Aim 1 examined feasibility create right atrial line block from...
Background: Pulsed field ablation (PFA) is a nonthermal energy that may provide safety advantages over radiofrequency (RFA). One-shot PFA catheters have been developed for pulmonary vein isolation, but they do not permit flexible lesion sets. This study investigated novel lattice-tip catheter designed focal RFA or ablation. Methods: The effects of (biphasic, 24 amperes) were in 25 swine using and system (Affera Inc). Step 1 (n=14) examined the feasibility to create atrial line block...
Background: The mitral isthmus is the critical element of perimitral reentrant tachycardias. Prolongation in transisthmus conduction time and differential pacing techniques are commonly used to determine block. However, these may not distinguish block from slow or via epicardial bridging connections. aim this study was examine standard criteria for line with endocardial activation mapping. Methods: In 56 patients, posterior performed using radiofrequency ablation. Conduction defined as (≥100...
Abstract Introduction Multielectrode mapping catheters improve the ability to map within heterogeneous scar. A novel Octaray catheter with eight spines and 48 electrodes may further speed resolution of atrial mapping. The aims this study were (1) establish Octaray's baseline performance electrogram (EGM) characteristics in healthy atria (2) determine its utility for identifying gaps a swine model ablation lines. Methods Results right mapped Pentaray (Biosense Webster, Irvine, CA) before...
Background Radiofrequency ablation of intramural ventricular substrate is often limited by insufficient tissue penetration despite high energy settings. As lesion dimensions have a direct and negative relationship to impedance, reducing the baseline impedance may increase effect on deep tissue. Methods This study included 16 patients with tachycardia or frequent premature complexes refractory irrigated catheters. After failed response radiofrequency ablation, was modulated adding...
Background: High-current short-duration radiofrequency energy delivery has potential advantages for cardiac ablation. However, this strategy is limited by high current density and narrow safety-to-efficacy window. The objective of study was to examine a novel using new electrode design capable delivering power at low increase the therapeutic range Methods: Sphere9 an expandable spheroid-shaped lattice with effective surface area 10-fold larger than standard irrigated electrodes (lattice...
Abstract Objective To adapt and validate an algorithm to ascertain transgender gender diverse (TGD) patients within electronic health record (EHR) data. Methods Using a previously unvalidated of identifying TGD persons administrative claims data in multistep, hierarchical process, we validated this EHR set with self-reported identity. Results Within 52 746 adults identity (gold standard) identify via TGD-related diagnosis procedure codes, gender-affirming hormone therapy prescription had...
Background We investigated national trends in volume and outcomes of percutaneous coronary angioplasty ( PCI ), artery bypass grafting CABG ischemic heart disease–related mortality Israel. Methods Results Using International Classification Diseases 9th 10th revision codes, we linked 5 Israeli databases, including the Israel Center for Disease Control National Registries, Ministry Health Hospitalization Report, Bureau Statistics, Interior Mortality to assess annual volume, procedural...
Multielectrode mapping catheters can be advantageous for identifying surviving myocardial bundles in scar. This study aimed to evaluate the utility of a new multielectrode catheter with increased number small and closely spaced electrodes ventricles healed infarction.In 12 swine (four healthy eight infarction), left ventricle was mapped investigational (OctarayTM) standard (PentarayTM) catheters. The has more (48 vs. 20), each smaller surface area (0.9 2.0 mm2) spacing is fixed at 2 mm (vs....
Background: Ventricular tachycardia ablation is often limited by insufficient lesion creation. A novel radiofrequency catheter with an expandable lattice electrode has a larger surface area capable of delivering higher currents at lower density to potentially increase dimensions without overheating. Methods: This 8F bidirectional irrigated (Sphere-9, Affera Inc) 9 mm spherical tip (“lattice”) effective 10-fold than standard linear catheters. Nine thermocouples provide temperature feedback...
Background: In infarct-related ventricular tachycardia (VT), the circuit often corresponds to a location characterized by activation slowing during sinus rhythm (SR). However, relationship between SR and vulnerability for reentry correlation components of VT are unknown. This study examined correlated these areas with circuit. Methods: porcine model healed infarction, spatial distribution endocardial velocity was compared VT. Isthmus sites were defined using entrainment mapping as exhibiting...
Gastric outlet obstruction can be a dangerous complication of intragastric balloons, as it result in severe metabolic alkalosis. As weight loss procedures and medical tourism become more popular, physicians should have high index suspicion for complications invasive procedures, particularly returning travelers.
Physical inactivity is a known risk factor for atrial fibrillation (AF). Wearable devices, such as smartwatches, present an opportunity to investigate the relation between daily step count and AF risk.The objective of this study was association predicted 5-year AF.Participants from electronic Framingham Heart Study used Apple smartwatch. Individuals with diagnosed were excluded. Daily count, watch wear time (hours days), self-reported physical activity data collected. Individuals' estimated,...
Exhaled carbon monoxide (eCO) is associated with subclinical and overt cardiovascular disease stroke. The association between eCO left atrial size, prevalent, or incident fibrillation (AF) are uncertain.