A5101760107- Heat shock proteins research
- Cancer-related gene regulation
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Health disparities and outcomes
- Dementia and Cognitive Impairment Research
- Occupational and environmental lung diseases
- Cancer-related Molecular Pathways
- Pituitary Gland Disorders and Treatments
- Protein Structure and Dynamics
- Phytase and its Applications
- Ubiquitin and proteasome pathways
- ATP Synthase and ATPases Research
- Potato Plant Research
- Health and Well-being Studies
- Health, Environment, Cognitive Aging
- Cancer, Lipids, and Metabolism
- Plant-Derived Bioactive Compounds
- Frailty in Older Adults
- Adrenal Hormones and Disorders
- Cancer, Hypoxia, and Metabolism
- Heart rate and cardiovascular health
- Adrenal and Paraganglionic Tumors
- Angiogenesis and VEGF in Cancer
- Endoplasmic Reticulum Stress and Disease
- Autophagy in Disease and Therapy
Guangxi Normal University
2025
Southern Medical University
2016-2024
Sun Yat-sen University
2016-2020
Sun Yat-sen University Cancer Center
2016-2020
Meizhou City People's Hospital
2018-2020
State Key Laboratory of Oncology in South China
2016-2019
Nanfang Hospital
2019
This study aims to assess the relationship between modifiable dementia risk factors and both cognitive decline. Data were obtained from Health Retirement Study (HRS) [2008-2020], China Longitudinal (CHARLS) [2011-2020], English of Ageing (ELSA) [2010-2020]. After adjusting for confounding factors, multivariable logistic regression was utilized analyze dementia, while linear employed examine these Additionally, Cox proportional hazards model used number factor events, clusters, risk. A total...
Abstract Solanine, a naturally steroidal glycoalkaloid in nightshade (Solanum nigrum Linn.), can inhibit proliferation and induce apoptosis of tumor cells. However, the mechanism solanine‐suppressing prostate cancer cell growth remains to be elucidated. This study investigates inhibition solanine on development vivo cultured human DU 145 vitro. Results show that injection significantly suppresses xenograft athymic nude mice. Solanine regulates protein levels cycle proteins, including Cyclin...
Fine particulate matter (PM2.5) airborne pollution increases the risk of chronic respiratory diseases, such as idiopathic pulmonary fibrosis (IPF), which is characterized by non-specific inflammation interstitial lung and extensive deposition collagen fibers. Type 2 alveolar epithelial cells (AEC2s) are stem in adult that contribute to repair process through complex signaling. Our previous studies demonstrated OGG1, a kind DNA enzyme, have critical role protecting from oxidative damage...
Objective: To investigate the association between sleep duration and activity of daily living (ADL) in elderly aged 65 years older China. Methods: A total 11 247 subjects above were included Chinese Elderly Health Factors Tracking Survey from March 29, 2005 to April 8, 2019. Self-made questionnaire was used collect data population sociological characteristics, health status disease status. ADL assessed by basic activities living. The impairment Cox proportional risk regression model....
Renal cell carcinoma (RCC) is the second most common human urinary tumor. Eupatilin main active ingredient of traditional Chinese medicine Artemisia asiatica . The effect on RCC and underlying mechanism remain unknown. Here, we investigated anticancer effects mechanisms in vivo vitro , laying an experimental foundation for clinical application treatment RCC. results showed that significantly inhibited 786-O viability migration promoted apoptosis. expression miR-21 cells, overexpression...
To investigate the impact of lifestyle, apolipoprotein E (ApoE) gene, and their interaction on risk for cognitive frailty in elderly population China.
Upregulated gene 11 (URG11), a new upregulated by hepatitis B virus X protein, is involved in the development and progression of several tumors, including liver, stomach, lung, colon cancers. However, role URG11 prostate cancer remains yet to be elucidated. By determined expression human tissues, was found significantly positively correlated with severity cancer, compared that benign prostatic hyperplasia tissues. Further, mRNA protein levels were cell lines (DU145, PC3, LNCaP), epithelial...
Apollon, namely baculoviral inhibitor of apoptosis proteins (IAP) repeat containing 6, is an unusually large member the IAP family, and may be important in oncogenesis. The aim present study was to assess association between renal carcinoma (RC) Apollon expression, highlight link expression occurrence, development prognosis RC. detected by immunohistochemistry, western blotting reverse transcription-quantitative polymerase chain reaction RC tissues, adjacent non-cancerous tissues paired...
OBJECTIVE To study the expression of BIRC6 in renal cancer tissues and investigate effect silencing on apoptosis autophagy 786-O cells. METHODS Twenty surgical specimens adjacent were collected from Meizhou People's Hospital between February, 2016 December, 2018 for detection protein using immunohistochemistry. Renal cells transfected with a control small interfering RNA (siRNA) or siRNA via lipofectamine 2000, changes cell proliferation following 5-FU treatment assessed CCK8 assay flow...
Objective: To explore the association between resting heart rate(RHR) and all-cause mortality among Chinese oldest-old aged more than 80. Methods: Using a total of seven surveys or follow-ups data (1998, 2000, 2002, 2005, 2008, 2011 2014) from Longitudinal Healthy Longevity Survey (CLHLS). A 17 886 elderly over 80 years old were selected as subjects, their rate measured though baseline survey survival outcome death time subjects followed up. The divided into 6 groups according to rate. Cox...
Objective To evaluate the clinical efficacy of single-port anatomical retroperitoneal laparoscopic adrenalectomy for trentment adrenal cysts. Methods From July 2010 to May 2015, adrenalectomies had been completed successfully in 12 patients with a homemade single port. The mean age was (47±8) years. Five cases on right side, and 7 left side. average diameter cyst (5.0±0.7) cm. Results Operations were performed using conventional equipment Laparoscopic excision cysts 4 remaining...