- Pericarditis and Cardiac Tamponade
- Infectious Diseases and Tuberculosis
- HIV/AIDS Research and Interventions
- Tuberculosis Research and Epidemiology
- Myasthenia Gravis and Thymoma
- Infective Endocarditis Diagnosis and Management
- Systemic Lupus Erythematosus Research
- Viral Infections and Immunology Research
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV/AIDS Impact and Responses
- Diagnosis and treatment of tuberculosis
- Lipoproteins and Cardiovascular Health
- Rheumatoid Arthritis Research and Therapies
- Probiotics and Fermented Foods
- Adolescent Sexual and Reproductive Health
- Global Health Workforce Issues
- Meat and Animal Product Quality
- Autoimmune and Inflammatory Disorders Research
- COVID-19 Clinical Research Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Protein Hydrolysis and Bioactive Peptides
- Cardiac electrophysiology and arrhythmias
- Adsorption and Cooling Systems
- HIV, Drug Use, Sexual Risk
- Cardiac Structural Anomalies and Repair
Stellenbosch University
2015-2024
Mundipharma (Germany)
2023
AbbVie (United States)
2023
Roche (Switzerland)
2023
Pfizer (United States)
2023
Novartis (France)
2023
Eli Lilly (Singapore)
2023
Cipla (United States)
2023
University Hospital Cologne
2013-2022
Tygerberg Hospital
2002-2021
The aim of the study was to investigate whether there is any structural evidence for model 'cognitive dysmetria' in schizophrenia if an automatic whole-brain analysis method used.High-resolution magnetic resonance scans were obtained 75 schizophrenic patients and controls.These data analysed using recently developed deformation-based morphometry allowing assessment volumetric differences without a priori definition regions interest.When compared with controls, we found reduced volumes...
Background Inequality is rife throughout South Africa. The first wave of COVID-19 may have affected people in lower socioeconomic groups worse than the affluent. SARS-CoV-2 seroprevalence and specificity anti-SARS-CoV-2 antibody tests Africa not known. Methods We tested 405 volunteers representing all strata from workforce a popular shopping tourist complex central Cape Town with Abbott IgG assay. assessed association between positivity symptom status, medical history, sociodemographic...
The aim was to establish the prevalence of large pericardial effusions in Western Cape Province South Africa, and determine incidence various types effusions. A total 233 patients presented with Each patient underwent tests for HIV, sputum smear culture, blood biochemistry serological testing. Tuberculous were diagnosed according pre-determined criteria. Eighty-four (36.1%) found be HIV positive; 81 these (96.4 %) had tuberculous pericarditis. More than 65% study population aged between 15...
Although there is growing literature on the psychological responses to and psychopathology associated with HIV/AIDS, few investigations have focused role of gender. This study compared psychiatric morbidity, coping responses, disability in male female outpatients recently diagnosed HIV/AIDS.One hundred forty-nine patients (44 male, 105 female) HIV/AIDS (mean +/- standard deviation (SD) months since diagnosis 5.8 4.1) attending an infectious diseases clinic at Tygerberg Hospital, Cape Town,...
This study examined the prevalence of unprotected sex, other sexual risk behaviours, and factors associated with sex among men women recently diagnosed HIV in South Africa. One hundred forty-nine outpatients (44 males 105 females) were assessed, whom 101 sexually active at least 6 months prior to entry. Subjects asked about behaviours reference their most recent encounter. Logistic regression analysis was employed determine predictors condom use, independent variables selected from five...
ABSTRACT Drug resistance among children with culture-confirmed tuberculosis (TB) provides an accurate measure of transmitted drug within the community. We describe genotype diversity in TB and investigate relationship between resistance. A prospective study was conducted from March 2003 through August 2005 at Tygerberg Children's Hospital, Western Cape Province South Africa. All (<13 years age) diagnosed were included. Genotype analysis phenotypic susceptibility testing performed on first...
Background: The last 50 years have seen major changes in the epidemiology of infective endocarditis (IE).
Background Systemic lupus erythematosus (SLE) is a life-threatening multisystem autoimmune disease that more severe in patients of African ancestry and children, yet pediatric SLE on the continent has been understudied. This study describes cohort (PULSE) South Africa. Methods Patients with diagnosis (1997 American College Rheumatology criteria) diagnosed prior to age 19 years Cape Town, Africa, were enrolled this cross-sectional from September 2013 December 2014. Information clinical...
African American ethnicity is independently associated with lupus myocarditis compared other ethnic groups. In the mixed racial population of Western Cape, South Africa, no data exists on clinical features/outcome myocarditis.The objective this study was to give a comprehensive description features and outcome acute in population.Clinical records (between 2008 2014) adult systemic erythematosus (SLE) patients at tertiary referral centre were retrospectively screened for echocardiographic...
Processed cheese foods were prepared by replacing young Cheddar solids with those of whey protein concentrates (WPC) obtained ultrafiltration Tilsit whey.Firrnness processed decreased in a highly significant manner (P< 0.01), while melting quality increased ( P< 0.01) the increase moisture over wide range.An amount and trisodium citrate improved firmness (P < but had deleterious effect on foods. food 1 flrmness 1melting concentrate additionRésumé -Fermeté et aptitude à la fusion de fromages...