A5090263642- Animal Disease Management and Epidemiology
- Vector-Borne Animal Diseases
- Animal Virus Infections Studies
- Viral Infections and Immunology Research
- Viral gastroenteritis research and epidemiology
- Influenza Virus Research Studies
- Microbial infections and disease research
- Respiratory viral infections research
- Virus-based gene therapy research
- Agriculture and Farm Safety
- Viral Infections and Vectors
- Viral Infectious Diseases and Gene Expression in Insects
- Bayesian Modeling and Causal Inference
- Herpesvirus Infections and Treatments
- Fault Detection and Control Systems
- Anomaly Detection Techniques and Applications
- Animal Behavior and Welfare Studies
- Zoonotic diseases and public health
- Natural Language Processing Techniques
- Vector-borne infectious diseases
- Biomedical Text Mining and Ontologies
- Virology and Viral Diseases
- Genetic and phenotypic traits in livestock
- Bacillus and Francisella bacterial research
- Dutch Social and Cultural Studies
Wageningen University & Research
2009-2019
Netherlands Food and Consumer Product Safety Authority
2012
Cardiovascular Institute of Philadelphia
2011
Friedrich-Loeffler-Institut
2011
University of Veterinary Medicine Hannover, Foundation
2011
Veterinary and Agrochemical Research Centre
2011
Institute of Virology of the Slovak Academy of Sciences
2011
De Gezondheidsdienst voor Dieren
1996-2009
GGz centraal
2008
The declaration of the human influenza A pandemic (H1N1) 2009 (H1N1/09) raised important questions, including origin and host range [1], [2]. Two three pandemics in last century resulted spread virus to pigs (H1N1, 1918; H3N2, 1968) with subsequent independent establishment evolution within swine worldwide [3]. key public veterinary health consideration context evolving is whether H1N1/09 could become established pig populations [4]. We performed an infection transmission study...
ABSTRACT The emergence in humans of the A(H1N1)pdm09 influenza virus, a complex reassortant virus swine origin, highlighted importance worldwide surveillance swine. To date, large-scale studies have been reported for southern China and North America, but such data not yet described Europe. We report first genomic characterization 290 viruses collected from 14 European countries between 2009 2013. A total 23 distinct genotypes were identified, with 7 most common comprising 82% incidence....
Swine influenza causes concern for global veterinary and public health officials. In continuing two previous networks that initiated the surveillance of swine viruses (SIVs) circulating in European pigs between 2001 2008, a third Surveillance Network Influenza Pigs (ESNIP3, 2010–2013) aimed to expand widely knowledge epidemiology SIVs. ESNIP3 stimulated programs harmonized SIV countries supported coordination appropriate diagnostic tools subtyping methods. Thus, an extensive virological...
Infections with Schmallenberg virus (SBV) are associated congenital malformations in ruminants. Because reporting of suspected cases only could underestimate the true rate infection, we conducted a seroprevalence study Netherlands to detect past exposure SBV among dairy cattle. A total 1,123 serum samples collected from cattle during November 2011-January 2012 were tested for antibodies against by using neutralization test; was 72.5%. Seroprevalence significantly higher central-eastern part...
At the end of 2011, a new orthobunyavirus, tentatively named Schmallenberg virus (SBV), was discovered in Germany. This has since been associated with clinical signs decreased milk production, watery diarrhoea and fever dairy cows, subsequently also congenital malformations calves, lambs goat kids. In affected countries, initial surveillance for infection based on examination malformed progeny. These suspicions were followed up by real-time reverse transcription polymerase chain reaction...
We investigated whether ASF carrier pigs that had completely recovered from an acute infection with ASFV Netherlands '86, could transmit the disease to naive by direct contact transmission. For this, we used survived infection, disease, and become carriers of ASFV. These clinically healthy were put together one-by-one pigs. Two twelve developed infection. Using results experiment quantified transmission parameters βcarrier (0.039/day) Tcarrier (25.4 days). With survival rate 0.3 for our...
African swine fever (ASF) is a fatal disease for domestic pigs, leading to serious economic losses in countries where ASF endemic. Despite extensive research, efficient vaccines against are lacking. Since peripheral blood cells important mediators vaccines, we study the impact of on parameters pigs with different ages and infected doses virus. Four groups were studied: (1) 12 weeks age/low virus dose; (2) age/high (3) 18 (4) dose. By varying age and/or ASFV inoculation dose, monitor during...
The aim of this study was to evaluate the general characteristics commercially available enzyme-linked immunosorbent assays (ELISAs) detect antibody against classical swine fever (CSF), as well assess their potential use accompanying marker tests able differentiate infected from vaccinated animals (DIVA). Chekit* CSF-Sero and HerdChek* CSFV Ab, both which antibodies E2 protein virus (CSFV), had highest sensitivity. Both were practicable showed good reproducibility. Comparable sensitivity...
Pigs have long been hypothesized to play a central role in the emergence of novel human influenza A virus (IAV) strains, by serving as mixing vessels for mammalian and avian variants. However, key issue viral persistence swine populations at different scales is ill understood. We address this gap using epidemiological models calibrated against seroprevalence data from Dutch finishing pigs estimate ‘critical herd size’ (CHS) IAV persistence. then examine phylogenetic evidence comparing IAV....
Outbreaks of respiratory disease constitute a major health problem in herds finishing pigs and their aetiology often remains unclear. In this study, 16 outbreaks with acute clinical signs were investigated to determine which infectious agents involved. From each herd four diseased two clinically healthy examined pathologically for the presence viruses, bacteria mycoplasmas. addition, paired blood samples from 10 groupmates tested antibodies against commonly known causal disease. A clear...