- Acupuncture Treatment Research Studies
- Pulmonary Hypertension Research and Treatments
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Traditional Chinese Medicine Studies
- Ferroptosis and cancer prognosis
- Healthcare and Venom Research
- Privacy, Security, and Data Protection
- User Authentication and Security Systems
- Gut microbiota and health
- Privacy-Preserving Technologies in Data
- Cancer-related molecular mechanisms research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Phytochemistry and Biological Activities
- Cell Image Analysis Techniques
- Biofield Effects and Biophysics
- Sodium Intake and Health
- Image and Object Detection Techniques
- Human Pose and Action Recognition
- Reproductive Biology and Fertility
- Neonatal and fetal brain pathology
- Functional Brain Connectivity Studies
- Forensic Anthropology and Bioarchaeology Studies
- Mental Health Research Topics
- Cardiovascular Health and Disease Prevention
Soochow University
2024
Xinxiang Medical University
2024
Sun Yat-sen Memorial Hospital
2024
Sun Yat-sen University
2024
Guangdong Academy of Medical Sciences
2024
Shenyang Aerospace University
2024
Southern Medical University
2024
Guangdong Provincial People's Hospital
2024
China Medical University
2024
Duke University
2012-2023
Infertility affects approximately 10–15% of couples worldwide who are attempting to conceive, with male infertility accounting for 50% cases. Male is related various factors such as hormone imbalance, urogenital diseases, environmental factors, and genetic factors. Owing its relationship cannot be diagnosed through routine examination in most cases, clinically called ‘idiopathic infertility.’ Recent studies have provided evidence that microRNAs (miRNAs) expressed a cell-or stage-specific...
Potential blood pressure- (BP-) lowering mechanisms of the DASH dietary pattern were measured in 20 unmedicated hypertensive adults a controlled feeding study. At screening, participants averaged 44.3 ± 7.8 years, BMI 33.9 6.6 Kg/m(2), and BP 144.2 9.38/88.5 6.03 mmHg. All consumed control diet for one week, then randomized to or another two weeks (week two). With DASH, but not controls, SBP fell by 10.65 12.89 (P = 0.023) 9.60 11.23 0.039) mmHg DBP 5.95 8.01 0.069) 8.60 9.13 0.011) at end...
Protein kinase A (PKA)/cAMP response element-binding (CREB) protein signaling pathway, contributing to impaired neurogenesis parallel depressive-like behaviors, has been identified as the crucial factor involved in antidepressant of acupuncture. However, molecular mechanisms associated with acupuncture, neurogenesis, and behaviors ameliorating remain unexplored. The objective was identify underlying acupuncture through PKA pathway depression rats by employing inhibitor H89 vivo experiments....
Abstract: Ruminococcus gnavus ( R. gnavus) is a gram-positive anaerobe commonly resides in the human gut microbiota. The advent of metagenomics has linked with various diseases, including inflammatory bowel disease (IBD), obesity, and diabetes mellitus (DM), which become growing area investigation. initial focus research primarily centered on assessing abundance its potential association presentation, taking into account variations sample size, sequencing analysis methods. However, recent...
The extracellular signal-regulated kinase (ERK) signaling pathway is considered to be associated with the pathogenesis and treatment of depression. Acupuncture has been demonstrated ameliorate depression-related behavior promote neurogenesis. In this study, we explored role ERK in antidepressant-like effects acupuncture rats exposed chronic unpredictable mild stress (CUMS). Eighty male Sprague–Dawley were randomly divided into eight groups: control group, model + group (Acu group),...
PurposeGemcitabine is a basic chemotherapy drug for pancreatic cancer (PC), but resistance common and causes tumor recurrence metastasis. Therefore, it significant to explore gemcitabine resistance-related molecules individualized treatment prognosis assessment of PC.MethodsIn this study, transcriptome sequencing TCGA database analysis were performed, differentiated gene AHNAK2 was screened. MEXPRESS database, tissue microarray analysis, CIBERSORT TIMER databases used correlate expression...
Abstract Background Hypoxic pulmonary hypertension (HPH) is a challenging lung arterial disorder with remarkably high incidence and mortality rates, the efficiency of current HPH treatment strategies unsatisfactory. Endothelial-to-mesenchymal transition (EndMT) in artery plays crucial role HPH. Previous studies have shown that lncRNA-H19 (H19) involved many cardiovascular diseases by regulating cell proliferation differentiation but H19 EndMT has not been defined. Methods In this research,...
We aim to investigate the therapeutic effect of dauricine on ulcerative colitis (UC). Our results indicated that attenuated reduction colonic length, weight loss, disease activity index, tissue damage, and inflammatory cytokine levels in dextran sulfate sodium mice. In addition, reduced lipopolysaccharide-induced inflammation HT-29 cells. Mechanically, docked with p65, a member nuclear transcription factor kappaB (NF-κB) family, through which release from Together, above inferred had for UC...
Dynamic obstacle avoidance is crucial for a robot to achieve autonomous and safe navigation, especially in complex ever-changing indoor environments. The needs detect obstacles timely manner dynamically plan path. To accomplish this, an environment perception system established using RGB-D depth camera IMU unit, providing the with multimodal information such as 3D vision orientation angles. Firstly, improved target detection model based on YOLOv7-tiny constructed. This utilizes algorithm...
To investigate the effect of acupuncture intervention on depression behavior and expression extracellular signal-regulated protein kinases (ERK 1/2), p-ERK 1/2 brain-derived neurotrophic factor (BDNF) in prefrontal cortex chronic unpredictable mild stress (CUMS) induced rats, so as to explore its antidepressant mechanism.Sixty-four male SD rats were randomly divided into control, model, acupuncture, Fluoxetine, model + Dimethyl sulfoxide (DMSO), PD 98059(an ERK pathway inhibitor), 98059...
<title>Abstract</title> Background Hypoxic pulmonary hypertension (HPH) is a challenging lung arterial disorder with remarkably high incidence and mortality rates, the efficiency of current HPH treatment strategies unsatisfactory. Endothelial-to-mesenchymal transition (EndMT) in artery plays crucial role HPH. Previous studies have shown that lncRNA-H19 (H19) involved many cardiovascular diseases by regulating cell proliferation differentiation but H19 EndMT has not been defined. Methods In...
In TCM theory, the syndrome is crucial to diagnose diseases and treat patients. identification, relation of symptoms usually correlates with represents pattern at symptomatic level. Hence, we learn models for classifying syndromes in depression using 4 different algorithms, which are naive Bayes, Bayes network, SVM C4.5. From results classification, find that dependence has something do accuracies classification. Then, 8 symptom networks corresponding 7 constructed explore interaction...
Purpose: The meridian system is originated from concept of invisible line which connects between internal organ and specific point in the body surface. And points are discovered by observing reaction patients after pushing patient’s skin with doctor’s hand. it so called Ashipoints means make patient scream “Ah!”. In this study, we suppose that ashi-points have relation referred pain, thus observed an aspect revelation pain area visualized evans blue dye. Methods: SD-rats (250 g) were...
Purpose: we will prove the clinical effect of acupunctural treatment to anti-depression. Methods: According principle informed consent and wishes patients, participants were divided into two groups, 35 for acupuncture group(acupuncture treatment), 25 western medicine group(SSRI). Hamilton scales have been evaluated at 0,1,2,4,6,8,12 weeks period. Results: 1. The significant difference effects between groups was detected(P 0.05). 2. There cure rate groups(P<0.05),acupuncture group...