A5100770414- Acne and Rosacea Treatments and Effects
- Genetic Associations and Epidemiology
- RNA modifications and cancer
- Genomics and Chromatin Dynamics
- Dermatology and Skin Diseases
- Herpesvirus Infections and Treatments
- Video Surveillance and Tracking Methods
- Transgenic Plants and Applications
- Thyroid Disorders and Treatments
- Kruppel-like factors research
- Food Allergy and Anaphylaxis Research
- Genetic Mapping and Diversity in Plants and Animals
- Stock Market Forecasting Methods
- Intracerebral and Subarachnoid Hemorrhage Research
- Thyroid Cancer Diagnosis and Treatment
- RNA Research and Splicing
- Cardiac, Anesthesia and Surgical Outcomes
- Immunodeficiency and Autoimmune Disorders
- Embedded Systems and FPGA Design
- Human Pose and Action Recognition
- Complex Systems and Time Series Analysis
- Intensive Care Unit Cognitive Disorders
- Skin Protection and Aging
- Simulation and Modeling Applications
- Neuroinflammation and Neurodegeneration Mechanisms
Central South University
2023-2025
Xiangya Hospital Central South University
2023-2025
Xi'an Jiaotong University
2017-2025
Jinan University
2021
Yunnan University
2018-2020
Guangdong Provincial People's Hospital
2011
Rosacea is a chronic inflammatory skin disorder, whose underlying cellular and molecular mechanisms remain obscure. Here, we generate single-cell atlas of facial from female rosacea patients healthy individuals. Among keratinocytes, subpopulation characterized by IFNγ-mediated barrier function damage found to be unique lesions. Blocking IFNγ signaling alleviates rosacea-like phenotypes in mice. The papulopustular featured expansion pro-inflammatory fibroblasts, Schwann, endothelial...
ABSTRACT Background Post‐laser melasma induction/exacerbation remains a critical challenge in treating acquired bilateral nevus of Ota‐like macules (ABNOMs). While laser parameters are well‐studied, patient‐specific risk factors across evolving therapeutic eras require elucidation. Methods This retrospective cohort analyzed 2675 ABNOMs patients treated with Q‐switched lasers two eras: C1 (2010–2013; 1064 nm‐only, n = 1069) and C2 (2020–2023; multi‐wavelength, 1606). Risk were assessed...
Abstract Background Rosacea is a chronic inflammatory skin disease. The diagnosis based on the symptoms and physical signs, which still lacks objective laboratory tests or imaging tests. Objectives To propose evaluate upper eyelid network pattern in rosacea. Methods Participants included patients diagnosed with rosacea, other facial erythematous diseases, normal controls, all of whom underwent full‐face utilizing VISIA® system software. According to these images, researchers evaluated...
With the development and gradually popularized application of next-generation sequencing technologies (NGS), genome has been becoming faster cheaper, creating a massive amount sequence data which still grows at an explosive rate. The time cost transmission, storage, processing analysis these genetic have become bottlenecks that hinder genetics biomedicine. Although there are many common compression algorithms, they not effective for sequences due to their inability consider exploit inherent...
Abstract Aim Genome‐wide association studies ( GWAS ) have identified multiple susceptibility loci associated with insulin resistance IR )‐relevant phenotypes. However, the genes responsible for these associations remain largely unknown. We aim to identify ‐relevant phenotypes via a transcriptome‐wide study. Materials and Methods conducted large‐scale multi‐tissue study (Insulin Sensitivity Index, homeostasis model assessment‐IR, fasting insulin) lipid‐relevant traits (high‐density...
Background. One-third to half of IgA nephropathy (IgAN) patients have raised serum levels. Decreased clearance IgA/IgA complex has been observed in IgAN patients. FCAR codes for IgA-specific receptor and plays an important role metabolism. Previous small sample-sized studies reported controversial findings its association with IgAN. Methods. We re-sequenced the 107 112 controls. Association −27T/C their haplotypes were performed 606 versus controls, two independent subsets: 293 single family...
Thyroid dysfunction is a common endocrine disease measured by thyroid-stimulating hormone (TSH) level. Although >70 genetic loci associated with TSH have been reported through genome-wide association studies (GWASs), the variants can only explain small fraction of thyroid function heritability. To identify novel candidate genes for function, we conducted first large-scale transcriptome-wide study (TWAS) using GWAS-summary data levels in up to 119 715 individuals combined precomputed gene...
A method to compress aeroengine test data is discussed in this paper. Three characteristics of are analyzed firstly. They limited value range, variation range and precision. Based on the characteristics, four processes including reducing decimal digits, eliding sign bit, repeated redundant coding bits utilized data. Additional information needed for compression decompression too Two examples with real show that can very low ratio.
The event-based quantitative trading system can avoid human subjective judgment errors in the stock and futures markets, development of strategies based on "high probability" events history obtain ideal returns. It is essentially a discrete event processing system. uses computer to simulate process random with high probability. core its engine part driven by transaction data. These data be regarded as series events. This article summarizes introduces strategy-driven open source framework...