Yukun Mei

ORCID: 0000-0003-4780-7605
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About
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Research Areas
  • Oral microbiology and periodontitis research
  • RNA modifications and cancer
  • Nanoplatforms for cancer theranostics
  • Esophageal Cancer Research and Treatment
  • Adipokines, Inflammation, and Metabolic Diseases
  • Innovations in Medical Education
  • Ferroptosis and cancer prognosis
  • Dental Education, Practice, Research
  • Cancer-related molecular mechanisms research
  • Corrosion Behavior and Inhibition
  • Metal and Thin Film Mechanics
  • Polymer Surface Interaction Studies
  • Salivary Gland Disorders and Functions
  • Sirtuins and Resveratrol in Medicine
  • Medical and Biological Ozone Research
  • Autophagy in Disease and Therapy
  • Inflammasome and immune disorders
  • Photoacoustic and Ultrasonic Imaging
  • Radiology practices and education
  • 2D Materials and Applications
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Literature, Magical Realism, García Márquez
  • Planarian Biology and Electrostimulation
  • Perovskite Materials and Applications
  • Protease and Inhibitor Mechanisms

Xi'an Jiaotong University
2022-2025

Nanjing Medical University
2019-2025

Jiangsu Province Hospital
2023-2025

China University of Petroleum, Beijing
2024

Stomatology Hospital
2019

ABSTRACT Sirtuin 1 (Sirt1), a protein deacetylase, is novel target for bone metabolism. To investigate whether overexpression of Sirt1 in mandibular mesenchymal stem cells (M-MSCs) increased alveolar mass vivo, we generated transgenic mice (Sirt1TG), with gene expression driven by the Prx1 gene, which represents lineage. Our results demonstrated that M-MSCs volume 1-month-old, 9-month-old, and 18-month-old Sirt1TG compared age-matched wild-type (WT) mice, ovariectomized WT stimulating M-MSC...

10.1002/jbmr.3677 article EN Journal of Bone and Mineral Research 2019-01-28

Considering the high recrudescence and long-lasting unhealed large-sized wound that affect aesthetics cause dysfunction after resection of maxillofacial malignant skin tumors, a groundbreaking strategy is urgently needed. Photothermal therapy (PTT), which has become complementary treatment however, powerless in tissue defect regeneration. Therefore, novel multifunctional sodium nitroprusside Fe

10.1186/s12951-024-02409-4 article EN cc-by Journal of Nanobiotechnology 2024-04-23

Abstract High recurrence rates and critical bone defects after surgical treatment seriously hinder the curing rate of malignant tumors. Thus, developing a multifunctional platform to achieve effective tumor elimination regeneration is urgently needed. Recently, gas therapy combined with hyperthermia has shown an intriguing synergetic therapeutic effect on tumor, avoiding limited spot areas, insufficient heat in deep or surrounding regions, other inherent limitations photothermal therapy....

10.1002/bmm2.70011 article EN cc-by BMEMat 2025-04-19

Schematic diagram of the preparation process polydopamine-metal ion coating and functional verification coating.

10.1039/d5ra00301f article EN cc-by-nc RSC Advances 2025-01-01

The aim of this research was to investigate the functions Piezo channels in dentin defect, including mechanical signalling and odontoblast responses.

10.1016/j.identj.2023.07.002 article EN cc-by-nc-nd International Dental Journal 2023-10-11

Background The psychological status of Chinese postgraduate students majoring in stomatology after the COVID-19 restrictions still remains unclear. objective this study is to evaluate mental through a cross-sectional survey and gather related theoretical evidence for intervention on stomatology. Methods An online was administered, subjective well-being, anxiety, stress depression symptoms were assessed using 5-item World Health Organization Well-Being Index (WHO-5), item Generalized Anxiety...

10.3389/fpubh.2024.1376540 article EN cc-by Frontiers in Public Health 2024-05-03

Mini clinical evaluation exercise (mini-CEX) and objective structured examination (OSCE) are widely acknowledged as effective measures of resident standardization training (RST) in European American countries. However, China primary mini-CEX OSCE forms mainly limited undergraduate examination. Little knowledge is available regarding the validity right way /OSCE system advanced dental education so far. This study aimed to explore whether combination represents a global-dimension assessment...

10.1186/s12909-022-03956-w article EN cc-by BMC Medical Education 2022-12-22

Abstract Background Esophageal cancer is associated with high incidence and mortality worldwide. Differential expression genes (DEGs) weighted gene co-expression network analysis (WGCNA) are important methods to screen the core as bioinformatics methods. Methods The DEGs WGCNA were combined hub genes, pathway enrichment analyses performed on module in WGCNA. CCNB1 was identified based intersection between greenyellow Expression levels prognostic values of verified UALCAN, GEPIA2, HCMDB,...

10.1186/s12935-021-01826-x article EN cc-by Cancer Cell International 2021-02-25

Periodontitis is a prevalent oral disease that can significantly impact patients' life quality and systemic health. However, non-surgical subgingival scaling largely compromised due to poor patient compliance, leading high recurrence rate of periodontitis. Therefore, this research aims explore new approaches enhance the effectiveness existing local drug administration therapies.

10.1016/j.identj.2024.05.013 article EN cc-by-nc-nd International Dental Journal 2024-08-01

A novel spherical MoS2/WO3 composite was fabricated via a hydrothermal method for the photocatalytic degradation of RhB from wastewater. The structure and morphology photocatalyst were systematically characterized. nanospheres formed p-n heterojunction, with charge migration following Z-scheme mechanism. composites exhibited superior activity, achieving 94.5% rate in just 60 min under visible light irradiation, far surpassing performance pure WO3 MoS2. This enhanced activity attributed to...

10.3390/catal15010003 article EN Catalysts 2024-12-24

Abstract Objective Mini clinical evaluation exercise (mini-CEX) and objective structured examination (OSCE) are widely acknowledged as effective measures of resident standardization training (RST) in European American countries. However, China primary mini-CEX OSCE forms mainly limited undergraduate examination. Little knowledge is available regarding the validity right way /OSCE system advanced dental education so far. This study aimed to explore whether combination represents a...

10.21203/rs.3.rs-1493771/v1 preprint EN cc-by Research Square (Research Square) 2022-03-31

Abstract Background Esophageal cancer is associated with high incidence and mortality worldwide. Differential expression genes (DEGs) weighted gene co-expression network analysis (WGCNA) are important methods to screen the core as bioinformatics methods. Methods The DEGs WGCNA were combined hub genes, pathway enrichment analyses performed on module in WGCNA. CCNB1 was identified based intersection between greenyellow Expression levels prognostic values of verified UALCAN, GEPIA2, HCMDB,...

10.21203/rs.3.rs-120258/v2 preprint EN cc-by Research Square (Research Square) 2021-02-10
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