Mark‐Christoph Ott

ORCID: 0000-0003-4823-8280
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About
Contact & Profiles
Research Areas
  • Pesticide and Herbicide Environmental Studies
  • Bioinformatics and Genomic Networks
  • Gene expression and cancer classification
  • Environmental Toxicology and Ecotoxicology
  • Single-cell and spatial transcriptomics
  • Weed Control and Herbicide Applications
  • Biomedical Text Mining and Ontologies
  • Insect symbiosis and bacterial influences
  • Legume Nitrogen Fixing Symbiosis
  • Cell Image Analysis Techniques
  • Plant Pathogens and Fungal Diseases
  • Animal testing and alternatives
  • Plant tissue culture and regeneration
  • Plant Molecular Biology Research
  • Nematode management and characterization studies
  • Insect and Pesticide Research
  • Insect Pest Control Strategies
  • Insects and Parasite Interactions
  • Dermatological diseases and infestations
  • Insect Resistance and Genetics
  • Semantic Web and Ontologies
  • Photosynthetic Processes and Mechanisms

Bayer (Germany)
2014-2024

Summary Weed control failures due to herbicide resistance are an increasing and worldwide problem that significantly affect crop yields. Metabolism‐based (referred as metabolic resistance) in weeds is not well characterized at the genetic level. An RNA ‐Seq transcriptome analysis was used find candidate genes conferred diclofop a diclofop‐resistant population (R) of major global weed Lolium rigidum . A reference c DNA (19 623 contigs) assembled assigned putative annotations. Global gene...

10.1111/tpj.12514 article EN The Plant Journal 2014-03-22

Abstract The bed bug, Cimex lectularius , has re-established itself as a ubiquitous human ectoparasite throughout much of the world during past two decades. This global resurgence is likely linked to increased international travel and commerce in addition widespread insecticide resistance. Analyses C. sequenced genome (650 Mb) 14,220 predicted protein-coding genes provide comprehensive representation that are traumatic insemination, reduced chemosensory repertoire related obligate...

10.1038/ncomms10165 article EN cc-by Nature Communications 2016-02-02
Jahed Ahmed Oluwafemi Alaba Gazala Ameen Vaishali Arora Mario A Arteaga-Vazquez and 95 more Alok Arun Julia Bailey-Serres Laura Bartley George W. Bassel Dominique C. Bergmann Edoardo Bertolini Kaushal Kumar Bhati Noel Blanco‐Touriñán Steven P. Briggs Javier Brumós Benjamin Buer Adrien Burlaocot Sergio Alan Cervantes-Pérez Sixue Chen Bruno Contreras‐Moreira Francisco J. Corpas Alfredo Cruz‐Ramírez Cesar L. Cuevas‐Velazquez Josh T. Cuperus Lisa I David Stefan de Folter Peter Denolf Pingtao Ding William P Dwyer Matthew M. S. Evans Nancy George Pubudu Handakumbura Maria J Harrison Elizabeth S. Haswell Venura Herath Yuling Jiao Robert E. Jinkerson Uwe John Sanjay Joshi Abhishek Joshi Lydia-Marié Joubert Ramesh Katam Harmanpreet Kaur Yana Kazachkova Sunil K. Kenchanmane Raju Mather Ali Khan Rajdeep S. Khangura Ajay Kumar Arun Kumar Pankaj Kumar Pradeep Kumar Dhruv Lavania Tedrick Thomas Salim Lew Mathew G. Lewsey Chien-Yuan Lin Dianyi Liu Le Liu Tie Liu Ansul Lokdarshi Ai My Luong Iain C. Macaulay Sakil Mahmud Ari Pekka Mähönen Kamal Kumar Malukani Alexandre P. Marand Carly A Martin Claire D. McWhite Devang Mehta Miguel Miñambres Martín Jenny C. Mortimer Lachezar A. Nikolov Tatsuya Nobori Trevor M. Nolan Aaron J. Ogden Marisa S. Otegui Mark‐Christoph Ott José M. Palma Puneet Paul Atique ur Rehman Maida Romera‐Branchat Luís C. Romero Ronelle Roth Saroj Kumar Sah Rachel Shahan Shyam Solanki Bao‐Hua Song Rosangela Sozzani Gary Stacey Anna N. Stepanova Nicolas L. Taylor Marcela K. Tello‐Ruiz Tuan M. Tran Rajiv Kumar Tripathi Batthula Vijaya Lakshmi Vadde Tamás Varga Marija Vidović Justin W. Walley Zhiyong Wang Renate Weizbauer James Whelan

With growing populations and pressing environmental problems, future economies will be increasingly plant-based. Now is the time to reimagine plant science as a critical component of fundamental science, agriculture, stewardship, energy, technology healthcare. This effort requires conceptual technological framework identify map all cell types, comprehensively annotate localization organization molecules at cellular tissue levels. framework, called Plant Cell Atlas (PCA), for understanding...

10.7554/elife.66877 article EN cc-by eLife 2021-09-07

Abstract The pollen beetle M eligethes aeneus is the most important coleopteran pest in E uropean oilseed rape cultivation, annually infesting millions of hectares and responsible for substantial yield losses if not kept under economic damage thresholds. This species primarily controlled with insecticides but has recently developed high levels resistance to pyrethroid class. aim present study was provide a transcriptomic resource investigate mechanisms resistance. cDNA sequenced on both R...

10.1111/imb.12099 article EN Insect Molecular Biology 2014-04-07

Environmental risk assessment traditionally relies on a wide range of in vivo testing to assess the potential hazards chemicals environment. These tests are often time-consuming and costly can cause test organisms' suffering. Recent developments reliable low-cost alternatives, both vivo- silico-based, opened door reconsider current toxicity assessment. However, many these new approach methodologies (NAMs) rely high-quality annotated genomes for surrogate species regulatory Currently, lack...

10.1021/acs.est.3c08701 article EN cc-by-nc-nd Environmental Science & Technology 2024-01-21

Generalization of transcriptomics results can be achieved by comparison across experiments. This generalization is based on integration interrelated studies into a compendium. Such focus the bigger picture enables both characterizations fate an organism and distinction between generic specific responses. Numerous methods for analyzing datasets exist. Yet, most these gene-wise dimension reduction to obtain marker genes gene sets for, example, pathway analysis. Relying only isolated biological...

10.1093/plphys/kiab325 article EN PLANT PHYSIOLOGY 2021-07-16

Weed control failures due to herbicide resistance are an increasing and worldwide problem significantly impacting crop yields. Herbicide increased metabolism in weeds is not well characterized at the genetic level. An RNA-Seq transcriptome analysis was used identify genes conferring metabolism-based (MBHR) a population (R) of major global weed (Lolium rigidum), which diclofop-methyl experimentally evolved through recurrent selection from susceptible (S) progenitor population. A reference...

10.5073/jka.2014.443.007 article EN Julius-Kühn-Archiv 2014-02-11

Abstract Generalization of transcriptomics results can be achieved by comparison across experiments, which is based on integration interrelated studies into a compendium. Both characterization the fate organism as well distinguishing between generic and specific responses gained in such broader context. There are numerous methods for analyzing data sets, most focusing gene-wise dimension reduction to obtain marker genes gene e.g. pathway analysis. Relying only isolated biological modules...

10.1101/2020.11.16.384305 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2020-11-17

Abstract Environmental risk assessment traditionally relies on a wide range of in vivo testing to assess the potential hazard chemicals environment. These tests are often time-consuming, costly and can cause test organisms’ suffering. Recent developments reliable low-cost alternatives, both - silico -based, opened door reconsider current toxicity assessment. However, many these new approach methodologies (NAMs) rely high quality annotated genomes for surrogate species regulatory Currently,...

10.1101/2023.10.11.561851 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2023-10-14
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