Nassim Ait Abdallah
A5058052371- Systemic Sclerosis and Related Diseases
- Venous Thromboembolism Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Atrial Fibrillation Management and Outcomes
- Hemoglobinopathies and Related Disorders
- Acute Myocardial Infarction Research
- Inflammatory Myopathies and Dermatomyositis
- Dermatologic Treatments and Research
- Mast cells and histamine
- Systemic Lupus Erythematosus Research
- Blood groups and transfusion
- Eosinophilic Disorders and Syndromes
- Iron Metabolism and Disorders
- Pharmacogenetics and Drug Metabolism
- Autoimmune Bullous Skin Diseases
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Blood donation and transfusion practices
- Peripheral Neuropathies and Disorders
- Herpesvirus Infections and Treatments
- Long-Term Effects of COVID-19
- Diagnosis and Treatment of Venous Diseases
- Drug-Induced Ocular Toxicity
- Hematological disorders and diagnostics
- Lymphoma Diagnosis and Treatment
Assistance Publique – Hôpitaux de Paris
2016-2025
Sorbonne Université
2023-2024
University of Rochester
2024
Pitié-Salpêtrière Hospital
2024
Hôpital Charles-Foix
2023
Recherche clinique appliquée à l'hématologie
2020-2022
Hôpital Saint-Louis
2020-2022
Universidad Católica San Antonio de Murcia
2021-2022
Hospital Universitari Germans Trias i Pujol
2020-2022
Université Paris Cité
2021-2022
Erythrocytapheresis (ER) can improve outcome in patients with sickle cell disease (SCD). A good vascular access is required but frequently it be difficult to obtain for patients. Arterio-venous fistulas (AVFs) have been suggested ER SCD supported by limited evidence. We report the largest cohort of performed AVFs from three French reference centers. Data undergoing center were retrospectively collected. The inclusion criteria were: SS or Sβ-Thalassemia and AVF surgery ER. SCD-related...
Key Points Low %HbF is independently associated with silent WMCs on brain imaging in adults SCD. Our results highlight the potential use of therapeutic strategies inducing HbF expression SCD patients white matter changes.
There is little known about SARS-CoV-2 infection in patients with systemic autoinflammatory disease (SAID). This study aimed to describe epidemiological features associated severe form and death. Mortality between without SAID hospitalised for was compared.A national multicentric prospective cohort conducted from the French Rheumatic Musculoskeletal Diseases (RMD) COVID-19 cohort. Patients were matched non-SAID on age±7 years, gender number of comorbidities consider important confounding...
Background Blood transfusion is the cornerstone treatment to reduce clinical severity of sickle cell disease (SCD), but we need maintain haematocrit (Hct) within an acceptable range avoid a deleterious increase in blood viscosity. The aim this study was compare effects manual versus automated red (RBC) Exchange on haematological parameters and Study design methods This prospective, single‐centre, open nonrandomized observational included forty‐three patients: 12 had RBC 31 Exchange. Samples...
The Scleroderma Patient-centered Intervention Network (SPIN) developed an online self-management program (SPIN-SELF) designed to improve disease-management self-efficacy in people with systemic sclerosis (SSc, or scleroderma). aim of this study was evaluate feasibility aspects for conducting a full-scale randomized controlled trial (RCT) the SPIN-SELF Program. This embedded SPIN Cohort and utilized cohort multiple RCT design. In design, at time enrollment, participants consent be assessed...
Abstract Objective To evaluate extent of interstitial lung disease (ILD) and oesophageal involvement using high-resolution computed tomography (HRCT) in early diffuse SSc patients after autologous haematopoietic stem cell transplantation (aHSCT). Methods Overall chest HRCT, function skin score changes were evaluated 33 consecutive before aHSCT during yearly routine follow-up visits between January 2000 September 2016. Two independent radiologists blindly assessed the ILD semi-quantitative...
Abstract Background Systemic sclerosis (scleroderma; SSc) is a rare autoimmune connective tissue disease. Functional impairment of hands common. The Scleroderma Patient-centered Intervention Network (SPIN)-HAND trial compared effects offering access to an online self-guided hand exercise program usual care on function (primary) and functional health outcomes (secondary) in people with SSc at least mild limitations. Methods pragmatic, two-arm, parallel-group cohort multiple randomized...
Systemic sclerosis is a heterogenous disease in which little known about patterns of patient-reported symptom clusters. We aimed to identify classes individuals with similar anxiety, depression, fatigue, sleep disturbance, and pain symptoms evaluate associated sociodemographic disease-related characteristics.
Systemic sclerosis (scleroderma; SSc) is a rare autoimmune connective tissue disease. We completed an initial feasibility trial of online self-administered version the Scleroderma Patient-centered Intervention Network Self-Management (SPIN-SELF) Program using cohort multiple randomized controlled (RCT) design. Due to low intervention offer uptake, we will conduct new with progression full-scale trial, two-arm parallel, partially nested RCT The SPIN-SELF has also been revised include...
Background Patients with inflammatory rheumatic and musculoskeletal diseases (iRMD) receiving mycophenolic acid (MPA) may have a less favourable outcome from COVID-19 infection. Our aim was to investigate whether MPA treatment is associated severe infection and/or death. Methods IRMD patients without highly suspected/confirmed were included in this observational multicentre study. The primary death rate secondary objectives determine the severity of length hospital stay. Outcome comparisons...
Systemic sclerosis (SSc) is a rare autoimmune disease (AD), characterised by early diffuse vasculopathy, activation of the immune response and progressive skin internal organ fibrosis. In severe SSc (dSSc), autologous hematopoietic stem cell transplantation (aHSCT) improves survival, despite its own risk complications transplant related mortality (TRM). We present herein case dSSc patient undergoing aHSCT with low dose cyclophosphamide conditioning sudden acute myopericarditis cardiogenic...
Introduction Adult patients who have suffered acute cardiac or pulmonary failure are increasingly being treated using extracorporeal membrane oxygenation (ECMO), a cardiopulmonary bypass technique. While ECMO has improved the long-term outcomes of these patients, neurological injuries can occur from underlying illness itself. Cerebral autoregulation (CA) allows brain to maintain steady perfusion during changes in systemic blood pressure. Dysfunctional CA is marker injury and worsen...
Background The COVID-19 pandemic has raised concerns about its psychological effects. Sleep disturbances, anxiety and/or depressive symptoms, post-traumatic stress symptoms have been reported in general population. Patients with chronic rheumatism, systemic autoimmune disease or auto-inflammatory disease, due to immunosuppression, are at risk of severe forms infection. Currently, there is little information on impact the mental health these more vulnerable patients. Objectives To compare...
<h3>Background</h3> Since Burt <i>et al.</i> first demonstrated in the ASSIST trial (1) that lung disease high-resolution computed tomography (HRCT) volumetric measurement decreased autologous hematopoietic stem cell transplantation (aHSCT) recipients and increased controls receiving cyclophosphamide iv one year after starting treatment, limited data have been reported concerning evolution of Systemic Sclerosis-Interstitial Lund (SSc-ILD) since its relationship with esophageal volume is...