A5040440251- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal Cancer Treatments and Studies
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Cancer Genomics and Diagnostics
- Gallbladder and Bile Duct Disorders
- Multiple and Secondary Primary Cancers
- Hepatitis B Virus Studies
- Radiomics and Machine Learning in Medical Imaging
- Gastric Cancer Management and Outcomes
- Hepatitis C virus research
- Genetic factors in colorectal cancer
- Liver physiology and pathology
- Tracheal and airway disorders
- Medical Imaging Techniques and Applications
- Colorectal Cancer Surgical Treatments
- Medical Imaging and Pathology Studies
- Lung Cancer Diagnosis and Treatment
- Macrophage Migration Inhibitory Factor
- Pediatric Hepatobiliary Diseases and Treatments
- COVID-19 and healthcare impacts
- Amoebic Infections and Treatments
The University of Tokyo
2014-2025
The University of Texas MD Anderson Cancer Center
2020-2025
American College of Surgeons
2022
National Cancer Institute
2022
University of Virginia
2022
Hospices Civils de Lyon
2022
Okinaka Memorial Institute for Medical Research
2019
Okinaka Memorial Adult Disease Research Institute
2019
Toranomon Hospital
2016-2018
Eastern Hepatobiliary Surgery Hospital
2017
Background hepatocarcinogenesis is considered a major cause of postoperative recurrence de novo hepatocellular carcinoma (HCC) in patients with liver cirrhosis (LC). The degree underlying injury has reportedly correlated surgical outcomes HCC. However, the pattern and annual rate HCC are still unclear.To clarify LC.Data from 799 who underwent curative hepatectomy for at Toranomon Hospital Johns Hopkins between January 1, 1995, December 31, 2014, were retrospectively collected analyzed. Of...
BACKGROUND Resection is the most effective treatment for HCC. However, postoperative morbidity common and its impact on long‐term oncological outcome remains unclear. METHODS Long‐term outcomes of 774 patients who underwent curative resection early stage HCC at Johns Hopkins Hospital Toranomon were investigated after stratifying by development overall infectious complications. RESULTS A minor or major complication developed in 281 65 patients, respectively, while mortality was 1.3% ( n =...
p.G12C mutations occur in approximately 3% of metastatic colorectal cancers (mCRC). Recently, two allosteric inhibitors
Abstract Background Most current models for predicting survival after resection of colorectal liver metastasis include largest diameter and number metastases as dichotomous variables, resulting in underestimation the extent risk variation substantial loss statistical power. The aim this study was to develop validate a new prognostic model patients undergoing including continuous variables. Methods A developed using data from who underwent at MD Anderson Cancer Center had RAS mutational data....
To evaluate the association of perioperative ctDNA dynamics on outcomes after hepatectomy for CLM.
Although the usefulness of adjuvant chemotherapy has been established in treatment for stages II/III colorectal cancer, its prognostic advantage liver metastases (CLM) remains controversial.Two hundred and nine patients who underwent curative resection CLM were reviewed. The potential was investigated 3 groups stratified by disease-free interval (DFI): synchronous (S-CLM), early metachronous (EM-CLM, DFI ≤1 year), late (LM-CLM, >1 year).Of 105 after surgery, 47 received uracil-tegafur...
Background Gadoxetic acid (Gd-EOB-DTPA)-enhanced MRI is superior to CT in the detection of colorectal liver metastases (CRLMs) smaller than 10 mm. However, few studies have used findings predict patients' long-term prognosis. Purpose To investigate relationship between Gd-EOB-DTPA–enhanced parenchyma peripheral CRLM and both pathologic vessel invasion Materials Methods This retrospective study included patients who underwent before curative surgery for CRLM, without neoadjuvant chemotherapy,...
The delicate rebalanced hemostatic status of liver transplant recipients may lead to both hemorrhagic and thrombotic tendencies in this population. aim study was investigate the association between pretransplant procoagulants/anticoagulants posttransplant bleeding thrombosis among living donor recipients. subjects were 403 consecutive with chronic disease. Perioperative variables, including preoperative values for procoagulants anticoagulants, assessed determine their hemorrhaging...
It is not known whether perioperative chemotherapy, compared with adjuvant chemotherapy alone, improves disease-free survival (DFS) in patients upfront resectable colorectal liver metastases (CLM). The aim of this study was to estimate the impact neoadjuvant 5-fluorouracil, leucovorin and oxaliplatin (FOLFOX) on DFS CLM.Consecutive who presented up five CLM at two Japanese French centres 2008-2015 were included study. Both institutions favoured FOLFOX, whereas groups systematically preferred...