A5058126008- Aquaculture Nutrition and Growth
- Prostate Cancer Treatment and Research
- Renal and related cancers
- Genetic Mapping and Diversity in Plants and Animals
- Wheat and Barley Genetics and Pathology
- MicroRNA in disease regulation
- Renal cell carcinoma treatment
- Reproductive biology and impacts on aquatic species
- Bladder and Urothelial Cancer Treatments
- Anesthesia and Pain Management
- GNSS positioning and interference
- Inertial Sensor and Navigation
- Physiological and biochemical adaptations
- Liver Disease and Transplantation
- Aquaculture disease management and microbiota
- Urological Disorders and Treatments
- Hydrology and Watershed Management Studies
- Cancer-related molecular mechanisms research
- Energy Load and Power Forecasting
- Hydrological Forecasting Using AI
- Prostate Cancer Diagnosis and Treatment
- Urinary and Genital Oncology Studies
- Organ Transplantation Techniques and Outcomes
- Neuroscience of respiration and sleep
- Oral Health Pathology and Treatment
Ministry of Agriculture and Rural Affairs
2024-2025
Qinghai University
2023-2025
Tsinghua University
2022-2025
Zhejiang University
2021-2024
Sun Yat-sen University
2013-2024
Third Affiliated Hospital of Sun Yat-sen University
2015-2024
China Academy of Information and Communications Technology
2020-2024
Gansu Provincial Hospital
2018-2024
Kunming University of Science and Technology
2024
Institute of High Energy Physics
2024
Background and Purpose Macrophages regulate iron homeostasis in the liver play important role hepatic ischaemia/reperfusion (I/R) injury. This study investigates of macrophages overload‐related hepatocyte damage during I/R. Experimental Approach Liver biopsies from patients undergoing partial hepatectomy with or without portal occlusion were recruited markers cell death macrophage extracellular traps (METs) detected. A murine I/R model was also established high‐iron diet‐fed mice....
Summary The AGAMOUS‐LIKE6 ( AGL6 )‐like genes are ancient MADS‐box and functionally studied in a few model plants. knowledge of these wheat remains limited. Here, by studying ‘double homoeolog mutant’ the gene tetraploid wheat, we showed that was required for development all four whorls floral organs with dosage‐dependent effect on floret fertility. Yeast two‐hybrid analyses detected interactions classes proteins ABCDE organ development. found to interact several additional proteins,...
Reactive oxygen species (ROS) play important roles during anther and pollen development. DNA damage may cause chromosome fragmentation that is considered to underlie elimination for haploid induction by matrilineal pollen, a key step in MATRILINEAL-based double breeding technology. But when how occurs unknown. We performed comparative studies of wheat pollens from the wild-type CRISPR/Cas9 edited mutant (mMTL). Chemical assays detected second wave ROS mMTL at three-nuclei-stage subsequently,...
The TCP family genes are plant-specific transcription factors and play important roles in plant development. TCPs have been evolutionarily functionally studied several plants. Although common wheat (Triticum aestivum L.) is a major staple crop worldwide, no systematic analysis of this has conducted. Here, we performed genome-wide survey found 66 that belonged to 22 homoeologous groups. We then mapped these on chromosomes were duplicated including the ortholog maize TEOSINTE BRANCHED 1....
Auxin signaling is essential for the development of grain size and weight, two important components crop yield. However, no auxin/indole acetic acid repressor (Aux/IAA) has been functionally characterized to be involved in wheat (Triticum aestivum L.) grains date. Here, we identified a Aux/IAA gene, TaIAA21, studied its regulatory pathway. We found that TaIAA21 mutation significantly increased length, width, weight. Cross-sections mutant revealed elongated outer pericarp cells compared those...
In this letter, a lowpass filter (LPF) is proposed based on modified complementary split-ring resonator (CSRR) which can be considered as traditional rectangular CSRR attached with two C-shaped structures, and composite composed of simple uniform line four stub-loaded stepped impedance resonators (SLSIRs) connected at the corners. The LPF was designed using first resonant points produced by resonator, operating mechanisms are investigated its equivalent models. fabricated measured. measured...
The kidney function of patients with chronic disease (CKD) is impaired irreversibly. Organ transplantation the only treatment to restore in CKD patients. assessment new potential therapeutic procedures relies heavily on experimental animal models, but it limited by its human predictive capacity. In addition, frequently used two-dimensional vitro renal cell models cannot replicate all features vivo situation. this study, we developed a three-dimensional (3D) organoid model from whole cells as...
Acute kidney injury (AKI) occurs in half of patients with septic shock, resulting unacceptably high mortality. However, effective preventive treatments are still lacking. We hypothesized that pretreatment lipoxin A4 (LXA4), known to promote inflammation resolution, may attenuate AKI via blocking crosstalk between and cellular senescence. In this study, rats developed following cecal ligation puncture (CLP), as evidenced by a dynamic increase serum creatinine, blood urea nitrogen, urinary...
Rationale: Peripheral nerve block is a traditional perioperative analgesic method for its precise pain control and low systemic toxicity.However, single dose of local anesthetic merely provides few hours analgesia, high results in irreversible toxicity, whereas continuous infusion anesthetics expensive complicated.Therefore, it necessary to develop long-acting sensory-selective safe analgesia.Methods: An injectable composite comprising ropivacaine-loaded poly (ε-caprolactone) electrospun...
Triploid rainbow trout is a hypoxia-sensitive fish species, and susceptible to death in summer with high water temperature induced acute hypoxia. The study was conducted evaluate the effect of protein diet carbohydrate on hypoxic tolerance triploid trout. Two isolipidic isoenergetic diets low protein-high level (LPHC) protein-low (HPLC) were specifically formulated. After feeding trial 80 days, two group treated challenge. Plasma biochemical parameters, hepatic anti-stress, antioxidant...
Background:The programmed death 1 (PD1)/programmed ligand (PDL1) targeted therapies have gained positive outcomes in several tumors, but the evidence of expression and prognosis value PD1/PDL1 high risk prostate cancer was rare.Methods: Immunohistochemical analysis PDL1/PD1 by a validated antibody performed retrospectively collected cohort who received adjuvant hormonal therapy (AHT) after radical prostatectomy (RP).The association between determined.Results: In total, 127 patients were...
Adhesion between circulating monocytes and vascular endothelial cells is a key initiator of atherosclerosis. In our previous studies, it was demonstrated that the expression connexin (Cx)43 in modulates cell adhesion, however, effects Cx43 remains to be elucidated. Therefore, present study investigated role process adhesion. A total four different methods with distinct mechanisms were used change function channels human umbilical vein cells: channel inhibitor (oleamide), enhancer (retinoic...
Internet data center buildings have great importance for maintaining the post-earthquake functionality of telecommunication networks. It is essential to maintain internet during earthquakes or recover immediately after earthquakes, which referred as seismic resilience. In this study, a resilience assessment framework based on Chinese code GB/T 38591-2020 introduced first. The damage and repair both structural components non-structural are considered in framework. A method loss quantification...