Kewen Chen

ORCID: 0009-0001-4143-0125
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About
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Research Areas
  • Brake Systems and Friction Analysis
  • Tribology and Wear Analysis
  • Gut microbiota and health
  • Micro and Nano Robotics
  • Railway Engineering and Dynamics
  • High-Velocity Impact and Material Behavior
  • Surface Treatment and Residual Stress
  • Advanced Materials and Mechanics
  • Erosion and Abrasive Machining
  • Advanced Decision-Making Techniques
  • Acute Kidney Injury Research
  • Advanced Sensor and Energy Harvesting Materials
  • Tryptophan and brain disorders
  • Geomagnetism and Paleomagnetism Studies
  • Biomimetic flight and propulsion mechanisms
  • Vibration Control and Rheological Fluids
  • Auditing, Earnings Management, Governance
  • Extracellular vesicles in disease
  • Geomechanics and Mining Engineering
  • Seismic Performance and Analysis
  • Advanced Computational Techniques and Applications
  • Solar-Powered Water Purification Methods
  • Web Data Mining and Analysis
  • Chronic Kidney Disease and Diabetes
  • Evaluation and Optimization Models

Fujian Agriculture and Forestry University
2022-2025

Life University
2025

Second Military Medical University
2024

Changhai Hospital
2024

Xiangtan University
2021-2023

Chongqing University
2022-2023

Nanjing Agricultural University
2022

Southwest Minzu University
2022

China Building Materials Academy
2021

Sichuan University
2008-2018

Type 2 diabetes mellitus (T2DM) is a chronic disease mainly caused by insufficient insulin secretion and resistance. In addition, T2DM often accompanied dysregulation of lipid metabolism inflammatory response. The effect oral administration Sanghuangporus vaninii mixture (SVM) on mice was evaluated. results showed that SVM intervention could change body weight glucose/lipid metabolism-related indicators. it can also improve the level factors to play protective role in pancreas jejunum. 16S...

10.1039/d2fo02268k article EN Food & Function 2022-01-01

Magnetically active soft materials (MASMs) demonstrate considerable potential for applications in sensors, biomedicines, and bionic robotics. However, owing to the low viscosity of unmodified MASMs with weak molding stacking ability, these cannot be printed directly, making fabrication complex structures. A modified MASM printing ink its preparation method are proposed problem material process 3D, effects fumed silica nanoparticles as modifier on rheological mechanical properties were...

10.1021/acsapm.3c00174 article EN ACS Applied Polymer Materials 2023-07-17

Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney (AKI). Recent findings suggest that Testis-Specific Protein Y-encoded-Like 2 (TSPYL2) plays fibrogenic role in diabetes-associated renal injury. However, the TSPYL2 IRI-induced damage not entirely clear. In this study, we found expression was upregulated mouse model AKI and hypoxia/reoxygenation (H/R) cell model. Knockdown attenuated after IRI. More specifically, knockdown or aminocarboxymuconate-semialdehyde...

10.1016/j.isci.2024.109594 article EN cc-by-nc-nd iScience 2024-03-27

As ubiquitous transport nanovesicles in cell biology, plant exosome-like vesicles (PELVs) have enormous potential to deliver drugs safely and effectively. Drug encapsulation mechanical stability of are key limitations influencing their delivery efficiency. However, common methods (i.e., ultrasound, electroporation) for drug loading inevitably affect the inherent vesicle characteristics, which influence stability, leakproof nature, cellular internalization, tumor penetration. Herein, order...

10.1021/acsnano.4c15440 article EN ACS Nano 2025-04-17

Magnetic soft materials (MSM) show excellent potential in robotics, biomedicine, and sensors because of their magnetic response, reversible deformation, controlled motion. A hard material (HASM) that can be obtained by adding particles to a matrix. By programing the spatial magnetization profile HASM object manipulating driving field, it exhibits shape manipulation performance with unconstrained, deformation transformation In this study, ink consisting NdFeB silicone rubber matrix was...

10.1177/1045389x231167797 article EN Journal of Intelligent Material Systems and Structures 2023-04-15

Resin-based friction materials have been widely used in the braking of automobiles and power machinery. Based on experiments for variation law wear morphology, a new model coefficient resin-based was proposed, which includes effects both micro convex body surface material frictional film generated during process. This quantitative established modelling shear strength, compressive strength film, contact load morphology. The morphology were adjusted by changing content basalt fibers flaky...

10.3390/ma16134791 article EN Materials 2023-07-03

BACKGROUND: Renal ischemia-reperfusion injury (IRI) is common in renal transplantation, shock, and nephrolithotomy. OBJECTIVE: To quantitatively assess rabbit IRI with contrast-enhanced ultrasound (CEUS) investigate associations between ren

10.3233/ch-131768 article EN Clinical Hemorheology and Microcirculation 2015-01-01

Abstract Under the action of an external magnetic field, particles will be arranged along direction field. The laws physics that control these processes are well described in literature. However, when move fluid, with different initial distances have mutual influences, so there motion. Therefore, based on motion theory Stokes this article discusses law contact and separation two circular Newtonian fluid. First, we conduct theoretical simulation modeling under a uniform verify correctness...

10.1088/1361-6463/ac353a article EN Journal of Physics D Applied Physics 2021-11-01

Insulin resistance is the major factor involved in pathogenesis of type 2 diabetes. Although oral drug metformin (MH) widely used to reduce hyperglycemia, it associated with adverse effects. Therefore, there an urgent need search for safe and natural foods that do not cause effects as alternatives commercial drugs. In this study, active substances from Spirulina platensis, Grifola frondosa, Panax ginseng, chromium-rich yeast were obtain functional formulations (SFFs), its therapeutic on mice...

10.1155/2022/3910116 article EN cc-by Oxidative Medicine and Cellular Longevity 2022-07-13

Abstract Additive manufacturing has been widely used in the field of bonded magnets manufacturing. However, there are some key issues to be faced order obtain (BMs) with high performance. In this study, four different particle sizes flake NdFeB powder (volume‐weighted mean diameter [VMD] 5.60 μm, 19.21 33.25 and 66.69 μm) were obtained by vibratory sieving. Flexible filaments for 3D printing BMs produced using polyamide‐6 (PA6) as substrate, production process is reported paper....

10.1002/pc.27007 article EN Polymer Composites 2022-08-26

Purpose Resin-based friction materials are the most widely used key in industry for braking and transmission. However, coefficient of resin-based significantly decreases at temperatures above 300°C, which reduces their performance. Design/methodology/approach This study combines elevated-temperature mechanical experiments with wear to explain thermal degradation resistance performance temperature recovery materials. It also investigates influence material strength worn morphology on elevated...

10.1108/ilt-07-2023-0233 article EN Industrial Lubrication and Tribology 2023-11-03

Abstract Sanghuangporus vaninii is a traditional edible and medicinal fungi with long history in China. Recent studies have focused on its potential treating diabetes, although the underlying mechanism remains unclear. This study aimed to investigate antidiabetic hypolipidemic effects of formula S. compounds (SVC) diabetic mice explore improvement intestinal microbiota. Oral administration SVC significantly reduced fasting blood glucose improved insulin sensitivity lipid indexes. In addition...

10.1002/efd2.70007 article EN cc-by eFood 2024-10-01

As an effective forming technique, peen is widely used in sheet metal components with large dimensions. However, the production efficiency seriously limited as several peening tests are required before actual production. To address this issue, a numerical simulation method of was proposed. In work, elastoplastic finite element model developed to study relations between process parameters and effects. A set different coverages velocities were conducted validate model. Results indicate that...

10.1177/09544089231207086 article EN Proceedings of the Institution of Mechanical Engineers Part E Journal of Process Mechanical Engineering 2023-10-17
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