A5053081284- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Health and Risk Factors
- Cardiovascular Function and Risk Factors
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Health disparities and outcomes
- Dementia and Cognitive Impairment Research
- Polymer Foaming and Composites
- Pneumonia and Respiratory Infections
- Alzheimer's disease research and treatments
- Cardiac Health and Mental Health
- Liver Disease Diagnosis and Treatment
- Folate and B Vitamins Research
- biodegradable polymer synthesis and properties
- Blood Pressure and Hypertension Studies
- Sepsis Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Gout, Hyperuricemia, Uric Acid
- Hip and Femur Fractures
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Facial Trauma and Fracture Management
- Ophthalmology and Eye Disorders
- Ocular and Laser Science Research
- Organ Transplantation Techniques and Outcomes
- Advanced Chemical Physics Studies
Capital Medical University
2022-2025
Beijing Tian Tan Hospital
2023-2025
National Clinical Research Center for Digestive Diseases
2023-2025
Yangzhou University
2023-2025
Beijing Institute of Neurosurgery
2024-2025
Northern Jiangsu People's Hospital
2023
Jiangxi Provincial People's Hospital
2023
Southwest Medical University
2023
Zhengzhou University
2017-2019
Lanzhou Army General Hospital
2016
Abstract Background Triglyceride glucose (TyG) index and its related parameters have been introduced as cost-effective surrogate indicators of insulin resistance, while prospective evidence their effects on atherosclerotic cardiovascular disease (ASCVD) remained scattered inconsistent. We aimed to evaluate the association TyG with new-onset ASCVD, predictive capacity were further compared. Method A total 95,342 ASCVD-free participants enrolled from Kailuan study. defined by fasting blood...
Evidence on the longitudinal associations between serum uric acid (SUA) and stroke was limited yielded inconsistent conclusions. We aimed to investigate of cumulative SUA (cumSUA), incorporating time course cumSUA accumulation, with risk stroke.The prospective cohort study enrolled 50 871 participants from Kailuan, China. CumSUA 2006 2010 derived by calculating means values consecutive examinations multiplying intervals visits. Time accumulation categorized as slope versus or splitting...
Background The American Heart Association recently proposed an updated definition of cardiovascular health (CVH) named as Life's Essential 8. We aimed to explore the association between this latest published CVH measurement and years lived without disease (CVD) among Chinese population. Methods Results included 89 755 adults free CVD at baseline from Kailuan study. each participant was scored (from 0 point 100 points) classified (low [0–49 points], moderate [50–79 high [80–100 points])...
Abstract Objective The objective of this study was to evaluate the associations general and central obesity with risk first cardiometabolic disease (FCMD), multimorbidity (CMM), death. Methods A total 86,169 participants who were CMD‐free included from Kailuan cohort categorized into four groups by quartiles BMI, waist hip ratio (WHR), weight‐adjusted index, height ratio. We defined FCMD as onset diabetes, stroke, or myocardial infarction CMM co‐occurrence at least two CMDs. Multistate...
To investigate the association between neuropsychiatric symptoms (NPS) and nutritional status, explore their shared regulatory brain regions on Alzheimer's disease (AD) continuum. A longitudinal, observational cohort study. Data were collected from Chinese Imaging, Biomarkers, Lifestyle study June 1, 2021 December 31, 2022. Overall, 432 patients AD continuum, including amnestic mild cognitive impairment dementia, assessed at baseline, only 165 completed (10.37 ± 6.08) months' follow-up. The...
Abstract INTRODUCTION Malnutrition correlates with neuropsychiatric symptoms (NPSs) in Alzheimer's disease (AD); however, the potential mechanism underlying this association remains unclear. METHODS Baseline and longitudinal associations of nutritional status NPSs were analyzed 374 patients on AD continuum 61 healthy controls. Serum biomarkers, behavioral tests, cerebral neurotransmitters, differentially gene expression evaluated standard malnourished diet–fed transgenic APPswe/PSEN1dE9...
We show that it is impossible to experimentally observe the quantum intrinsic orbital angular momentum (IOAM) effect without its axial current. Broadly speaking, we argue spiral or interference characteristics of current density determine occurrence nonlinear tunneling effects in any spacetimedependent systems. Our findings offer a comprehensive theoretical framework addresses limitations Keldysh theory and provides new insights into properties systems, particularly tunneling-dominated...
Complicated time-dependent curved spacetime and electric field are involved in many astrophysical situations, including the early universe, Hawking radiation, Schwinger effect, gravitational pair production. In this Letter, a generalized quantum two-level model (GQTLM) is developed, which applicable to arbitrary field. The found be consistent with kinetic theory, characterized by its simplicity versatility. momentum distribution of particles effects distortions can correctly described....
Recent Mendelian randomization and meta-analysis highlight the relevance of MCP-1 (monocyte chemoattractant protein-1) in stroke. We aimed to investigate associations between clinical outcomes patients with ischemic stroke or transient attack test whether inflammation mediates jointly contributes relationships.
Long-rod penetration in a wide range of velocity means that the initial impact varies from tens meters per second to several kilometers second. The long rods maintain rigid state when is low, nose rod deforms and even blunted gets higher, erodes fails lead consumption projectile very high due instantaneous pressure. That is, low velocity, undergoes rods, deforming non-erosive erosive rods. Because complicated changes projectile, no well-established theoretical model numerical simulation have...
Abstract Background High cardiovascular health (CVH) was associated with lower risk of disease (CVD) and longer life expectancy. However, whether years lived without CVD could increase faster than or at least the same pace as total lifespan remains unknown. We aimed to explore associations CVH status expectancy among middle-aged elderly men women. Methods included 65,587 participants aged ≥ 45 from Kailuan study, who were recruited during June 2006 October 2007. scored classified (low [0–49...
Stroke is a serious disease that threatens human health both in China and worldwide. Identifying establishing its risk factors are prerequisites for intervention evaluation of prognosis. Over the years, factors, such as age, diabetes, hypertension, have gradually been established. However, at present, there no consensus on influence sex prognosis ischaemic stroke.The aims our research was to analyse correlation between poststroke based results Third National Registry [CNSR-III], well other...
Abstract Background: Few evidence is available in the early prediction models of behavioral and psychological symptoms dementia (BPSD) Alzheimer’s disease (AD). This study aimed to develop validate a novel genetic–clinical–radiological nomogram for evaluating BPSD patients with AD explore its underlying nutritional mechanism. Methods: retrospective included 165 from Chinese Imaging, Biomarkers, Lifestyle (CIBL) cohort between June 1, 2021, March 31, 2022. Data on demoimagedatas,...
Abstract Background This study aimed to compare the predictive value of metrics unique stress-induced hyperglycemia (SIH) with fasting blood on poor functional outcomes spontaneous intracerebral hemorrhage (sICH). Methods investigation included 528 patients from a multicenter, observational, prospective cohort study. Poor were defined as modified Rankin Scale(mRS) ≥ 3. Logistic regression analyses used assess relationship between indicators SIH, including glucose (FBG), two definitions...
Background and Purpose: Single Small Subcortical Infarction (SSSI) is a subtype of ischemic stroke with unique pathophysiology, often leading to poor outcomes. This study investigates the association between admission hematocrit (HCT) levels risk progressive in SSSI patients. Methods: We conducted retrospective cohort using data from China National Stroke Registry III, including 2,457 Progressive was defined as an increase NIHSS score by 2 points during hospitalization. Logistic regression...
<title>Abstract</title> <italic><bold>Background</bold></italic> Triglyceride glucose (TyG) index and its related parameters has been introduced as cost-effective surrogate indicators of insulin resistance, while prospective evidence on their effects risk atherosclerotic cardiovascular disease (ASCVD) remained scattered inconsistent. We aimed to evaluate the association TyG with new-onset ASCVD further compare predictive capacity. <italic><bold>Method</bold></italic> A total 95,342...