A5009509729- Ocular Surface and Contact Lens
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Ophthalmology and Visual Impairment Studies
- Facial Rejuvenation and Surgery Techniques
- Extracellular vesicles in disease
- Corneal Surgery and Treatments
- Nasolacrimal Duct Obstruction Treatments
- Retinal Imaging and Analysis
- Intraocular Surgery and Lenses
- Ocular Diseases and Behçet’s Syndrome
- Complement system in diseases
- Hedgehog Signaling Pathway Studies
- Immunotherapy and Immune Responses
- Herpesvirus Infections and Treatments
- Retinal and Optic Conditions
- Mycobacterium research and diagnosis
- Acute Kidney Injury Research
- Cardiovascular Health and Disease Prevention
- Cancer and Skin Lesions
- Cytomegalovirus and herpesvirus research
- Autoimmune and Inflammatory Disorders
- Blood Pressure and Hypertension Studies
- Chronic Kidney Disease and Diabetes
Sungkyunkwan University
2012-2025
Catholic University of Korea
2018-2024
Yeouido St. Mary's Hospital
2020-2021
Weatherford College
2020-2021
Soongsil University
2021
Chuncheon Sacred Heart Hospital
2021
Hallym University
2021
Keio University
2021
Seoul St. Mary's Hospital
2018-2019
Kangbuk Samsung Hospital
2012
Abstract Recent studies suggested that an association exists between vision loss and cognitive impairment, although it is still vague whether there are causal relationships or direct low dementia. We were to investigate the dementia in Korean population using National Health Insurance Service (NHIS) database. analyzed data of 6,029,657 subjects aged ≥40 years, drawn from Korea Service. The hazard ratio (HRs) 95% confidence interval (CIs) dementia, Alzheimer’s disease (AD), Vascular (VD)...
Tumor-derived extracellular vesicles (TDEs) have potential for therapeutic cancer vaccine applications since they innately possess tumor-associated antigens, mediate antigen presentation, and can incorporate immune adjuvants enhanced efficacy. However, the original TDEs also contain immune-suppressive proteins. To address this, we proposed a simple yet powerful preconditioning method to improve overall immunogenicity of TDEs. This approach involved inducing endoplasmic reticulum (ER) stress...
To analyze the differences in vitreous cytokine profiles epiretinal membrane eyes with and without an ectopic inner foveal layer (EIFL).Sixty (32 EIFL 28 EIFL) were included. The samples collected during surgery for membrane. levels of measured using a multiplex bead analysis.The mean logMAR visual acuity was worse (0.42 vs. 0.37; P = 0.331) central thickness higher group (496.9 µm 434.2 µm; 0.007) than they EIFL. 164.1 ± 67.7 group. On analysis cytokines, CD163 (21529 pg/dL 10877 pg/dL;...
To investigate the risk factors of diabetic nephropathy in patients with retinopathy requiring panretinal photocoagulation (PRP) and visual prognosis.A retrospective review electronic medical records was conducted at Seoul St. Mary's Hospital, comprising 103 type 2 diabetes mellitus who underwent PRP from 1996 to 2005. Patients 1 mellitus, non-diabetic renal disease, retinal visually significant ocular high-risk proliferative retinopathy, advanced were excluded. The divided into three...
Abstract The impact of underweight on the risk developing primary open-angle glaucoma (POAG) is not known, although association between obesity and POAG has been well studied. We evaluated among patients by studying a nationwide cohort sample in South Korea. analyzed data from Korean National Health Insurance Research Database collected 2009 2012 for 17,000,636 aged 40 years or older. Newly diagnosed was identified using claims 2015. A total 442,829 individuals (2.60%) were classified as...
Abstract Background This study aimed to compare surgically induced astigmatism (SIA) on the anterior and total cornea during cataract surgery through a 2.2 mm steep meridian incision. Methods The included 69 left eyes of patients who had undergone surgery. were classified into three subgroups according preoperative meridian. Following phacoemulsification, an intraocular lens was inserted bag. keratometric measurements taken 12 months postoperatively, (automated keratometer keratometry [K]...
Purpose: To report long-term outcomes of topical ganciclovir (GCV) and corticosteroids in Korean patients with cytomegalovirus (CMV) corneal endotheliitis.Methods: This retrospective study included 13 eyes from CMV endotheliitis, a follow-up period 24.5 ± 8.2 months. The were consistently maintained 2% GCV 1% prednisolone acetate eyedrop.Results: All demonstrated unilateral typical coin-shaped keratic precipitates (KPs) or linear KP, positive polymerase chain reaction aqueous humor. After 2...
To investigate the impact of orthokeratology wear on meibomian glands in Korean pediatric population using tear interferometer.Fifty-three wearers and 79 non-lens were evaluated LipiView® II ocular surface interferometer which shows incomplete blink rate, average lipid layer thickness, meiboscores.No significant differences rate meiboscores for upper eyelids, but thickness lower eyelids significantly higher Ortho-K group than control (p = 0.024 0.007, respectively). Correlation analysis...
Abstract Background In the present study, we evaluated correlation between meibomian gland dropout and meibum quality in same central 8 glands of eyelid. Methods Ninety-nine eyes 91 patients with dry eye were included study. Dropout eyelids was graded as 0, 1, 2, or 3, according to area. The follows: grade no secretion; inspissated/toothpaste consistency; cloudy liquid clear secretion. For 68 patients, analysis performed. To precisely analyze direct meibography quality, 31 23 focal...
Abstract To analyze the relationship between systemic lipid profile levels and meibomian gland dysfunction (MGD) subtype in Korea. The ophthalmic data of 95 eyes serum profiles patients were reviewed. These factors compared with those general population using from Korean National Health Nutrition Examination Survey (KNHANES), which evaluated 2,917 subjects. Of these, comparison group (1:5 ratio; n = 475) was selected propensity score matching according to age sex. In addition, we analyzed...
Abstract Retinal vessels share similar anatomical and physiological characteristics with the cerebral microvasculature, abnormal blood flow is reportedly associated depressive disorder. However, there limited evidence regarding relationship between depression risk of retinal vein occlusion (RVO). This study aimed to investigate association prospective RVO using nationally representative longitudinal data. retrospective, nationwide, population-based cohort included 9,178,222 people aged 20...
Purpose: The purpose of this study was to investigate whether the intraocular lens (IOL) simulator can simulate how world appears patients with multifocal IOLs by allowing see far and near objects through IOL simulator. Methods: Twenty eyes from 20 (age = 50–70 years old) were included in study. we developed consists a trial frame adapter, tube, concave lens, spacer, wet cell, an IOL. We used two IOLs: Tecnis monofocal bifocal (add +3.25 diopter [D]). Patients wore on distant corrected...
Abstract To compare the risk of cancer development between patients with glaucoma and those without, we conducted a nationwide population-based cohort study using Korean National Health Insurance Database. Individuals diagnosis 2007 2016 were identified, controls 1:1 matched based on age sex. We calculated incidence rates(IR) hazard ratios(HR) before after adjusting for age, gender, diabetes, smoking history, body mass index. A total 107,536 individuals same number without included. The IR...
Purpose: The purpose of this study was to present a new surgical technique convert single roll Descemet membrane (DM) into double using 2 cannulas in balanced salt solution–filled Petri dish during DM endothelial keratoplasty. Methods: A stained with trypan blue placed dish. Two (28G) were introduced from opposite ends the roll, inserted and slowly spread apart change roll. aspirated modified Jones tube loaded, maintaining double-roll configuration endothelium-down orientation bevel-up...
Purpose: To compare corneal astigmatism, keratometry and higher order aberrations between the light emitting diode topography analyzer Scheimpflug Imager.Methods: This prospective study involved 45 patients (45 eyes) who visited Seoul St. Mary's hospital before cataract surgery from June 7, 2017, to August 2, 2017.For each eye, keratometry, astigmatism its axis of cornea, higher-order were evaluated with a Imager (Pentacam HR ® , Oculus, Wetzlar, Germany) color-LED topographer (Cassini...
Purpose: To report a case of pilomatrixoma that presented as periorbital area painful, perforating, rapidly growing mass. Case summary: A 35-year-old man with left lower mass 5 months duration. On examination, it measured 13 mm sized and was located at the lateral side area. The accompanied pain. perforation yellowish crust on observed. Conclusion: In patients presenting painful perforating mass, should be considered differential diagnosis solitary
Abstract Purpose Corneal asphericity ( Q ‐value) represents the difference in curvature from center to periphery of cornea. This study evaluated horizontal and vertical asymmetry corneal myopic children its relationship with various ocular parameters. Methods retrospective included 22 eyes 11 Korean children. parameters, such as thickness, apical radius curvature, high order aberrations including total RMS, spherical aberration, coma, trefoil were analyzed by Pentacam. Axial lengths anterior...
Abstract Purpose To compare meibomian gland (MG) morphology and function, blinking pattern in Korean pediatric subjects with or without overnight orthokeratology wear. Methods The retrospective study was conducted. Twenty‐eight participants were divided two groups: control ( n = 11) group 16). Control examined before OOK lens fitting during Meiboscore(0‐3), lipid layer thickness (um), quality (%) measured using LipiView ® II Ocular Surface Interferometer (TearScience, Morrisville, NC)....
Abstract Purpose: To analyze the correlation between systemic lipid profile levels and each meibomian gland dysfunction (MGD) subtype in Korea. Methods: The ophthalmic data of 95 eyes serum profiles patients were reviewed. These factors compared with those general population using from Korean National Health Nutrition Examination Survey (KNHANES), which evaluated 2,924 subjects. Of these, 475 propensity score-matched normal controls selected for comparison MGD based on a 1:5 ratio. In...