A5020497100- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Urticaria and Related Conditions
- Dermatology and Skin Diseases
- Ocular Infections and Treatments
- Facial Rejuvenation and Surgery Techniques
- Periodontal Regeneration and Treatments
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Proteoglycans and glycosaminoglycans research
- Skin Protection and Aging
- Allergic Rhinitis and Sensitization
- Wound Healing and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Hematopoietic Stem Cell Transplantation
- Connexins and lens biology
- Dermatologic Treatments and Research
- Mesenchymal stem cell research
- Ocular Diseases and Behçet’s Syndrome
- Nasolacrimal Duct Obstruction Treatments
- COVID-19 Impact on Reproduction
Yeouido St. Mary's Hospital
2016-2025
Catholic University of Korea
2016-2025
Smith-Kettlewell Eye Research Institute
2018-2019
Stanford University
2018-2019
Menlo School
2018
Seoul St. Mary's Hospital
2009-2016
Christie's
2016
Kim's Eye Hospital
2015
St. Mary’s Hospital
2010
To determine cytokine and chemokine concentrations in the tears of patients with dry eye disease (DED) analyze possible relationships clinical severity DED.Patients were examined using Ocular Surface Disease Index, corneal conjunctival staining, tear breakup time, impression cytology. They divided into four groups according to Dry Eye Workshop classification. Tears collected from 133 DED 70 healthy controls. Concentrations cytokines, chemokines, soluble receptors samples analyzed current...
To evaluate the therapeutic effect of allogeneic serum eye drops for treatment dry in patients with chronic graft-versus-host disease (cGVHD) following bone marrow transplantation.Sixteen cGVHD hematological stem cell transplantation (allo-SCT) and diagnosed syndrome refractory to conventional were prospectively enrolled this study. Allogeneic obtained from healthy related donors after serologic testing. Symptom scores, tear breakup time (tBUT), Schirmer test without anesthesia (Schirmer I...
In this study, an in situ forming corneal stromal substitute based on collagen type I crosslinked by bio-orthogonal strain-promoted azide-alkyne cycloaddition (SPAAC) is presented. The gel has greater transparency compared to non-crosslinked gels. mechanical properties of the gels are controlled changing functional group ratios and conjugated concentrations. Higher concentrations yield enhances properties, where storage modulus increases from 42.39 ± 8.95 112.03 3.94 Pa after SPAAC...
Abstract Background This study aimed to determine the relationship between dyslipidemia and dry eye disease (DED) in a Korean population. Methods population-based enrolled 5,627 adults (aged >19 years) who were participating first year of fifth annual Korea National Health Nutrition Examination Survey from 2010 2011. Clinically diagnosed DED its symptoms surveyed, biochemical blood analysis data collected. Dyslipidemia was defined as any following: hypercholesterolemia (total cholesterol...
The aim of this study was to investigate the influence overnight orthokeratology (OOK) on ocular surface and meibomian glands in children adolescents.Prospective, noncomparative included disease index (OSDI), tear osmolarity, corneal conjunctival fluorescein staining, film breakup time (TBUT), Schirmer I test, meiboscore using noncontact meibography. Immunofluorescence confocal microscopy interleukin-1β (IL1β), interleukin-6 (IL6), epidermal growth factor (EGF), matrix metalloproteinase...
Purpose To elucidate the prevalence of cataract, glaucoma, pterygia, and diabetic retinopathy among Korean postmenopausal women with or without estrogen replacement therapy (ERT). Methods A cross-sectional, nationally representative sample from 4th Korea National Health Nutrition Examination Survey (KNHANES IV) (2007–2009) was used. Participants were interviewed for determination socioeconomic gynecologic factors. Each woman also underwent an ophthalmologic examination provided a blood risk...
To assess corneal inflammation from alkali chemical burns, we examined the therapeutic effects of in situ-forming hyaluronic acid (HA) hydrogels crosslinked via blue light-induced thiol-ene reaction on a rat burn model. Animals were divided into three groups (n = 7 rats per group): untreated, treated with 0.1% HA eye drops, and hydrogels. Crosslinking hydrogel followed by administration drops carried out once day days 0-4. Corneal re-epithelialization, opacity, neovascularization, thickness,...
The purpose of this study was to investigate the dysfunction autonomic control that may be a contributing factor in normal tension glaucoma (NTG) by showing short-term heart rate variability NTG patients.Newly diagnosed patients and an age-matched group were enrolled prospective study. Blood pressure obtained electrocardiogram monitored for 5 minutes after 30-minute rest supine position. Electrocardiographic signals transferred analyzer. time frequency domain parameters analyzed between two...
Purpose: To evaluate the compatibility and usability of test results obtained from IDRA Keratograph 5M in clinical settings by comparing their performance patients with dry eye disease.Methods: From December 27 to 30, 2022, a study was conducted on 30 diagnosed utilizing both devices. The parameters compared analyzed included lipid layer thickness, tear meniscus height, film break-up time, meibography. A paired t-test used for statistical comparison. thickness graded scale 0 4 based...
Dry eye disease (DED) is a common disorder characterized by unstable tear film homeostasis. Its symptoms range from foreign body sensations to pain and fluctuations in visual function. Current diagnostics include physical examination ocular surface imaging. Matrix metalloproteinase-9 (MMP-9) tears correlates with clinical signs of DED; however, because the limited sample volume, quantitative real-time detection MMP-9 significant need, complicated biochemical complexity tears. We developed an...
We compared the 3-year outcomes with regard to efficacy, stability, and safety of LASIK surface ablation performed at multiple centers in Korea.The charts 5109 eyes that underwent or ablation, including LASEK, epi-LASIK, photorefractive keratectomy (PRK), between 2002 2005 were reviewed. Of these, 577 LASIK-treated propensity score-matched surface-ablated included this cohort study. A standardized case report form (CRF) was completed based on a review follow-up chart. The CRF preoperative,...
Abstract The available treatment options include corneal transplantation for significant defects and opacity. However, shortage of donor corneas safety issues in performing are the main limitations. Accordingly, we adopted injectable situ-forming hydrogels collagen type I crosslinked via multifunctional polyethylene glycol (PEG)-N-hydroxysuccinimide (NHS) evaluated vivo biocompatibility. New Zealand White rabbits (N = 20) were randomly grouped into keratectomy-only keratectomy with...
Sjögren's syndrome (SS) is a chronic systemic autoimmune disease affecting mainly middle-aged women [1].It has wide clinical spectrum that extends from sicca symptoms on the mucosal surfaces to extraglandular manifestations [2].Lymphocytic infiltration and destruction of exocrine glands (mainly salivary lacrimal glands) histologic hallmark SS, resulting in dry eye
To identify complications in the posterior eye segment patients who have undergone allogeneic hematopoietic stem cell transplantation (HSCT).This retrospective cohort study enrolled 747 with hematologic disease had HSCT at Seoul St. Mary's Hospital from January 2009 to December 2012. The were evaluated by reviewing information medical records Department of Hematology and Ophthalmology, including types, onset times, locations, resolution times according treatment periods for HSCT; addition, a...
Purpose: To compare changes in the anterior and posterior corneal parameters chamber depth (ACD) measured by a rotating Scheimpflug camera scanning-slit topography before after intrastromal ring segment (ICRS) implantation.Methods: Twenty-five eyes of 21 keratoconus patients who had Intacs (Addition Technology, Sunnyvale, CA) ICRS implantation were included. The participants 3 months with topography. Outcome measures included uncorrected (UDVA) corrected (CDVA) distance visual acuities,...