A5058183790- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- CAR-T cell therapy research
- Radiopharmaceutical Chemistry and Applications
- Monoclonal and Polyclonal Antibodies Research
- Immune Cell Function and Interaction
- Galectins and Cancer Biology
- Antibiotic Resistance in Bacteria
- NF-κB Signaling Pathways
- Cancer, Hypoxia, and Metabolism
- Ubiquitin and proteasome pathways
- Bacterial Identification and Susceptibility Testing
- Immunotherapy and Immune Responses
- Antibiotic Use and Resistance
- Circadian rhythm and melatonin
- Cytokine Signaling Pathways and Interactions
- Cannabis and Cannabinoid Research
- CRISPR and Genetic Engineering
- Healthcare Systems and Reforms
- Cancer Research and Treatments
- Vibrio bacteria research studies
- Peptidase Inhibition and Analysis
- Animal testing and alternatives
- Childhood Cancer Survivors' Quality of Life
- Urinary Tract Infections Management
University Medical Center HCMC
2020-2023
AbbVie (United States)
2023
St. John's University
2021
Santa Clara Valley Medical Center
2020
The University of Texas MD Anderson Cancer Center
2004-2018
University of Pittsburgh
2016-2018
// Jiayu Chen 1,2,* , Zijun Y. Xu-Monette 2,* Lijuan Deng 2 Qi Shen Ganiraju C. Manyam 3 Azahara Martinez-Lopez 4 Li Zhang Santiago Montes-Moreno Carlo Visco 5 Alexandar Tzankov 6 Lihui Yin Karen Dybkaer 7 April Chiu 8 Attilio Orazi 9 Youli Zu 10 Govind Bhagat 11 Kristy L. Richards 12 Eric D. Hsi 13 William W.L. Choi 14 J. Han van Krieken 15 Jooryung Huh 16 Maurilio Ponzoni 17 Andrés J.M. Ferreri Xiaoying Zhao 18 Michael B. Møller 19 John P. Farnen 20 Jane N. Winter 21 Miguel...
Abstract Purpose: Patients with B-cell lymphomas often relapse after frontline therapy, and novel therapies are urgently needed to provide long-term remission. We established lymphoma patient-derived xenograft (PDX) models assess their ability mimic tumor biology identify patient treatment options. Experimental Design: the PDX from 16 patients diffuse large lymphoma, mantle cell follicular marginal zone or Burkitt by inoculating cells into a human bone chip implanted mice. subjected...
Objectives: Antimicrobial resistance is a serious threat to health and economic well-being worldwide. The impact of antibiotic-resistant infections reflected by higher mortality, increased lengths hospital stay (LOS), healthcare costs. We analyzed the direct costs attributable treating patients infected with methicillin-resistant Staphylococcus aureus (MRSA) carbapenem-resistant Enterobacterales (CRE) in tertiary-care referral Vietnam. Methods: A retrospective descriptive cross-sectional...
Carbapenem-resistant Enterobacteriaceae (CRE) infection is an urgent threat to public health. The impact of CRE includes increased difficulty in treatment, and a high risk death. intensive care unit (ICU) patients are particularly vulnerable due severe illness comorbidities,. This study aims determine the prevalence identify associated factors ICU setting. cross-sectional was conducted at tertiary-level hospital, utilizing patient medical records gather data. population included aged 18...
Abstract Mantle cell lymphoma (MCL) is a rare and incurable subtype of B-cell lymphoma. In phase II study ibrutinib in MCL patients, most the patients responded had long durable remissions; however, 22.7% were considered to be non-responsive ibrutinib, an additional 22/110 displayed initial positive responses but also experienced disease progression within 12 months treatment, with both classified as primary resistant. Therefore, understanding mechanisms mediating resistance may identify new...
Abstract Lymphoma is the most common hematological malignancy, and B-cell lymphoma accounts for 85% of all lymphomas. The current overall cure rate estimated at ~30%, even with development application novel therapies, majority patients relapse after treatment due to drug resistance. evaluation targets using established cell lines limited by inexact correlation between responsiveness observed in line versus patient sample. However, patient-derived xenograft (PDX) mouse models have been shown...
e19536 Background: Diffuse large B-cell lymphoma (DLBCL) and mantle cell (MCL) represent the most common aggressive forms of Non-Hodgkin (NHL) respectively. Previous work has demonstrated CB1 antagonists as potential therapeutics for both DLBCL MCL. Our drug formulation VYR-206 was developed from existing obesity treatment Rimonabant, a antagonist, by addition our tetraazacyclic (N4) conjugate derivative. The N4 allows image guided theranostic application diagnosis, precision assessment...
Abstract Purpose: D-glucosamine has been reported to inhibit proliferation of cancer cells in culture and vivo. We have then synthesized Tc-99m- ethylenedicysteine-glucosamine (EC-DG). found Tc-99m-EC-DG was involved cell lung, breast head neck cultures could assess treatment outcome vivo by planar scintigraphy. is a safe imaging agent lung patients. This study amied (1) novel response unlabeled rhenium-EC-DG (Re-EC-DG) involving the translation regulation hypoxia inducible factor...