- Acute Ischemic Stroke Management
- Cerebrovascular and genetic disorders
- Moyamoya disease diagnosis and treatment
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Intracranial Aneurysms: Treatment and Complications
- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
- Tuberculosis Research and Epidemiology
- Neurological Disorders and Treatments
- Renal and Vascular Pathologies
- S100 Proteins and Annexins
- Respiratory Support and Mechanisms
- Inhalation and Respiratory Drug Delivery
- Venous Thromboembolism Diagnosis and Management
Center for Brooklyn History
2025
Brookdale University Hospital and Medical Center
2025
Cornell University
2023
Columbia University
2022-2023
Louisiana State University
2023
Saint Louis University
2023
Jackson Memorial Hospital
2023
University of Miami
2023
National Institute of Neurological Disorders and Stroke
2023
Introduction: Intracranial arterial calcifications (IAC) are considered a surrogate for intracranial large artery atherosclerosis but IAC can also represent non-atherosclerotic aging. People with have an increased risk of dementia. Nonetheless, the interplay between IAC, atherosclerosis, luminal stenosis and stiffness as determinants neurodegeneration remains unclear. Methods: We analyzed 161 brain autopsy cases from Brain Arterial Remodeling Study. dissected each components circle Willis...
Introduction: Previous studies have shown an association between vascular disease and Alzheimer’s disease, but there are few considered a relationship brain arterial remodeling biomarkers of Alzheimer's disease. Our study aims to find the specific characteristics in pathology. Method: We analyzed 132 autopsy cases from Brain Arterial Remodeling Study (BARS), collection brains multiple banks United States abroad. sections were obtained systematically by each bank, anatomical location was...
Red blood cell (RBC) concentrations are known to associate with ischemic stroke. It is unclear whether RBC specifically small vessel disease lacunar infarcts. We investigated the hypothesis that both chronic covert and acute symptomatic brain MRI
Introduction: CADASIL is the most common monogenic small-vessel disease (SVD) form. Large and small brain arteries are intimately related, but it unclear whether people with have changes in their large as a result. We hypothesized that patients affected compared to controls. Methods: conducted comparative analysis by matching 37 104 lacunar stroke from NYP/ Columbia University Medical Center Stroke Registry Study matched age +/-3 sex. measured basilar intracranial carotid artery diameters...
Introduction: Small vessel disease (SVD) is a condition associated with aging and vascular risk factors to which the brain kidney are susceptible. However, whether dysfunction may directly contribute SVD as opposed both organs being affected an epiphenomenon of less clear. We hypothesize that impaired function differentially markers SVD, association greater restricted deep, penetrating arteries. Methods: leveraged existing data from Columbia University Irving Medical Center/ New York...
Introduction: Age-related cognitive impairment is driven by the complex interplay of neurovascular and neurodegenerative disease. There a strong relationship between cerebral microbleeds (CMBs), amyloid angiopathy (CAA), decline observed in conditions such as Alzheimer’s In early, preclinical phase impairment, extent to which CMBs underlying CAA impact volumetric changed brain related disease remains unclear. Methods: We performed cross-sectional analyses from 3 large cohorts: The Northern...
Introduction: Early neurological deterioration (END) in patients with acute stroke is associated poorer outcomes. We aim to investigate whether higher phase reactants blood are END. Identifying predictors of END could help select patient at the highest risk for possible interventions. Methods: In this cross-sectional study, we included 242 onset ischemic admitted Columbia University Irving Medical Center-New York-Presbyterian Hospital from 2006 2015. focused on retrieving C-reactive protein...
Introduction: Stroke is one of the leading causes death worldwide. Our study aimed to investigate clinical variables that influence long-term mortality. Methods: A retrospective was done in patients admitted with stroke Columbia University Irving Medical Center - New York Presbyterian Hospital between 1990 and 2020 from whom data adjudication outcome were available at time analyses. classified as cardioembolic, large vessel, small vessel cryptogenic. We established 5 models which...