A5101795854- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Cytomegalovirus and herpesvirus research
- Pneumonia and Respiratory Infections
- Cancer Genomics and Diagnostics
- Cloud Computing and Resource Management
- Advancements in Battery Materials
- Gas Sensing Nanomaterials and Sensors
- Bacterial Infections and Vaccines
- Cancer-related molecular mechanisms research
- Streptococcal Infections and Treatments
- 3D Printing in Biomedical Research
- Extracellular vesicles in disease
- Bacterial Identification and Susceptibility Testing
- ZnO doping and properties
- Additive Manufacturing and 3D Printing Technologies
- interferon and immune responses
- RNA regulation and disease
- Aerogels and thermal insulation
- Genomics and Rare Diseases
- Chemotherapy-induced cardiotoxicity and mitigation
- PARP inhibition in cancer therapy
- Micro and Nano Robotics
- Magnesium Alloys: Properties and Applications
- Heat Transfer and Optimization
Henan University of Engineering
2024
Henan Energy & Chemical Industry Group (China)
2024
Gannan Medical University
2024
Chongqing University of Science and Technology
2024
Sun Yat-sen University
2024
The University of Queensland
2019-2024
State Key Laboratory of Respiratory Disease
2023-2024
Guangzhou Medical University
2023-2024
Sun Yat-sen University Cancer Center
2024
Shandong University of Science and Technology
2024
Metal-air battery is an environmental friendly energy storage system with unique open structure. Magnesium (Mg) and its alloys have been extensively attempted as anodes for air batteries due to high theoretical density, low cost, recyclability. However, the study on Mg-air (MAB) still at laboratory level currently, mainly owing anodic efficiency caused by poor corrosion resistance. In order reduce losses achieve optimal utilization of Mg anode, design strategies are reviewed from...
Three-dimensional (3D) printing thermosets offers great potential to customize sophisticated constructs for a myriad of applications.
Osteomyelitis, particularly chronic osteomyelitis, remains a major challenge for orthopedic surgeons. The traditional treatment which involves antibiotics and debridement, does not provide complete solution infection bone repair. Antibiotics such as vancomycin (VCM) are commonly used to treat osteomyelitis in clinical settings. VCM use is limited by lack of effective delivery methods that sustained, high doses entirely fill irregular tissue infections.We engineered chitosan (CS)-based...
This review summarizes the properties of stretchable hydrogels and their optimization for TENGs in on-skin electronics, highlighting applications addressing challenges related to durability user comfort.
There is currently no research on the diagnostic value of metagenomic next-generation sequencing (mNGS) for a single pathogens in CSF. The aim this study was to analyse mNGS identifying Streptococcus pneumoniae (S. pneumoniae) paediatric bacterial meningitis.Bacterial meningitis (BM) cases from October 23, 2014, December 31, 2016, and 1, 2017, July 2018 at Beijing Children's Hospital were reviewed. Clinical features analysed.We diagnosed 135 patients with BM study. A total 43 S. identified...
Theranostic nanoplatforms combining various diagnostic and therapeutic units together have attracted increasing attention over the past few decades. Owing to merits of non-invasiveness, spatiotemporal controllability, high treatment efficacy low normal-tissue damage, photothermal therapy (PTT) especially near-infrared-II (NIR-II, 1000–1700 nm) light-triggered PTT becomes one most popular modalities. Interestingly, agents (PTAs) used for often an intrinsic photoacoustic (PA) imaging function,...
Abstract Nanoengineering the composition and morphology of functional nanoparticles endows them to perform multiple tasks functions. An intriguing strategy for creating multifunctional nanomaterials involves construction core–shell nanostructures, which have enabled promising applications in biomedicine, energy, sensing, catalysis. Here, a straightforward nanoengineering approach is presented utilizing liquid metal galvanic replacement create diverse nanostructures. Controlled nanostructures...
Background and PurposezzEncephalitis caused by Listeria monocytogenes (L.monocytogenes) is rare but sometimes fatal.Early diagnosis difficult using routine cerebrospinal fluid (CSF) tests, while next-generation sequencing (NGS) increasingly being used for the detection characterization of pathogens.MethodszzThis study set up applied unbiased NGS to detect L. in CSF collected from three cases clinically suspected listeria meningoencephalitis.ResultszzThree patients with acute/subacute...
Aim: To investigate the influence of fluorine in reducing adsorption immune-reactive proteins onto PEGylated gold nanoparticles. Methods: Reversible addition fragmentation chain transfer polymerization, Turkevich method and ligand exchange were used to prepare polymer-coated Subsequent vitro physicochemical biological characterizations proteomic analysis performed. Results: Fluorine-modified polymers reduced complement other while potentially improving circulatory times modulating liver...
Intestinal immune dysregulation is strongly linked to the occurrence and formation of tumors. RING finger protein 128 (RNF128) has been identified play distinct immunoregulatory functions in innate adaptive systems. However, physiological roles RNF128 intestinal inflammatory conditions such as colitis colorectal cancer (CRC) remain controversial. To elucidate function mechanism CRC. Animal models dextran sodium sulfate (DSS)-induced azoxymethane (AOM)/DSS-induced CRC were established WT...
Tumor growth and metastasis are the major causes of high mortality in breast cancer. We previously constructed pH-sensitive nanoparticles (D/D NPs) for codelivery docetaxel (DTX) dihydroartemisinin (DHA) demonstrated that D/D NPs showed anticancer activity cancer cells vitro. The present study further investigated therapeutic effect on orthotopic vivo examined antitumor mechanism NPs. significantly increased apoptosis 4T1 with a synergistic DTX DHA. reactive oxygen species, reduced...
Abstract IL-3/STAT5 signaling pathway is crucial for the development and activation of immune cells, contributing to cellular response infections inflammatory stimuli. Dysregulation have been associated with autoimmune diseases characterized by cell infiltration organ damage. IL-3 receptor α (IL-3Rα) specifically binds initiates intracellular signaling, resulting in phosphorylation STAT5. However, regulatory mechanisms IL-3Rα remain unclear. Here, we identified E3 ubiquitin ligase RNF128 as...
Severe community-acquired pneumonia (SCAP) results in high mortality as well massive economic burden worldwide, yet limited knowledge of the bio-signatures related to prognosis has hindered improvement clinical outcomes. Pathogen, microbes and host are three vital elements inflammations infections. This study aims discover specific sensitive biomarkers predict outcomes SCAP patients.In this study, we applied a combined metagenomic transcriptomic screening approach specimens gathered from 275...