A5115596518- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Metabolomics and Mass Spectrometry Studies
- Physiological and biochemical adaptations
- Inflammasome and immune disorders
- Invertebrate Immune Response Mechanisms
- Insect and Pesticide Research
- Advanced Photonic Communication Systems
- Microbial Metabolic Engineering and Bioproduction
- Catalytic Processes in Materials Science
- Optical Network Technologies
- Biochemical effects in animals
- Pancreatic function and diabetes
- Amyotrophic Lateral Sclerosis Research
- Sphingolipid Metabolism and Signaling
- RNA modifications and cancer
- Ginseng Biological Effects and Applications
- Phytochemistry and Biological Activities
- CRISPR and Genetic Engineering
- Analytical Chemistry and Chromatography
- Hippo pathway signaling and YAP/TAZ
- Natural product bioactivities and synthesis
- Catalysis and Hydrodesulfurization Studies
- Advanced Fiber Laser Technologies
- Immune cells in cancer
Qingdao University
2024
Chongqing Public Health Medical Center
2024
Chongqing Medical University
2024
Qingdao Agricultural University
2020-2024
Guangdong University of Technology
2024
China Communications Construction Company (China)
2024
Tongji Hospital
2024
Hong Kong Polytechnic University
2024
Jingdong (China)
2024
Beijing Jishuitan Hospital
2024
Abstract The proficiency of phyllosphere microbiomes in efficiently utilizing plant-provided nutrients is pivotal for their successful colonization plants. methylotrophic capabilities Methylobacterium/Methylorubrum play a crucial role this process. However, the precise mechanisms facilitating efficient remain elusive. In present study, we investigate significance methanol assimilation shaping success mutualistic relationships between methylotrophs and A set strains originating from...
Using microarray analysis, we found that aging sarcopenia is associated with a sharp increase in the mRNA of matricellular protein CCN1 (Cyr61/CTGF/Nov). was upregulated 113-fold muscle aged vs. young rats. increased both rats (2.8-fold) and mice (3.8-fold). When progenitor cells (MPCs) were treated recombinant CCN1, cell proliferation decreased but there no change myogenic marker myoD. However, CCN1-treated MPCs did express senescence (SA-βgal). Interestingly, p53, p16(Ink4A), pRP...
Background Inflammation is recognized as an important contributor of ischemia/reperfusion (I/R) damage after ischemic stroke. Sphingomyelin synthase 2 ( SMS 2), the key enzyme for biosynthesis sphingomyelin, can function a critical mediator inflammation. In present study, we investigated role in mouse model cerebral I/R. Methods and Results Cerebral I/R was induced by 60‐minute transient middle artery occlusion knockout ‐/‐ ) mice wild‐type mice. Brain injury determined neurological deficits...
T-2 toxin treatment causes male reproduction system dysfunction, although the exact mechanism remains unclear. In this research, Kunming mice and TM4 cells were treated with varying concentrations of for evaluating adverse effect on reproductive function. MCC950 or NAC was used to block NLRP3 inflammasome activation eliminate reactive oxygen species (ROS) accumulation in cell, respectively. The results showed that: (1) caused testicular atrophy, destroyed microstructure ultrastructure...
This study examined whether diets with high dietary methionine levels could alleviate chronic heat stress in Chinese mitten crab Eriocheir sinensis. Crabs were fed three of 0.49%, 1.29% and 2.09% for six weeks. The analyzed concentration was 0.48%, 1.05% 1.72%, respectively. different supplemental concentrations at 24 °C 30 °C, trial divided into groups five replicates each group, 40 juvenile crabs (initial average weight 0.71 ± 0.01 g) replicate. During the trial, twice daily (the diet 4%...
Lymphocyte decline, particularly the depletion of NK cells, is a prominent feature immunosuppression following severe tissue injury, heightening susceptibility trauma patients to life-threatening infections. Previous research indicates that reduction in number cells closely associated with process cell death. Nonetheless, precise mechanism death remains unknown. Here, we discovered traumatic undergo several pathways, dominated by apoptosis and pyroptosis coexistence necrotic death,...
Evidence has shown that effects from inflammation and mitochondrial dysfunction lead to pyroptosis apoptosis of nucleus pulposus (NP) cells. Damaged mitochondria release dangerous molecules such as reactive oxygen species (ROS), activating the NLRP3 inflammasome. SS-31 is a mitochondria-targeting peptide been used in treatment many diseases by scavenging ROS ameliorating function. This study found ameliorated lipopolysaccharide (LPS)-induced loss cell viability, production, NP Moreover,...
Deoxynivalenol (DON) is the most common mycotoxin in food and feed, which can cause undesirable effects, including diarrhea, emesis, weight loss, growth delay livestock. Intestinal epithelial cells were main target of DON, oxidative stress inflammatory injury. Tanshinone IIA (Tan IIA) fat-soluble diterpene quinone, abundant active ingredient salvia miltiorrhiza plant with antioxidant anti-inflammatory characteristics. However, it not clear whether Tan protect against or inhibit intestinal...
Insecticides are commonly utilized in agriculture and forestry for pest control, but their dispersal can pose hazards to humans environment. Understanding resistance, inheritance patterns, fitness costs help manage resistance. A λ-cyhalothrin-resistant population (LCR) of
The Sox family of HMG (high mobility group)‐box transcription factors are highly conserved in vertebrates. members involved various developmental processes. Among them Sox17 has been demonstrated to function as an endoderm determinant zebrafish and Xenopus , respectively. However, little is known about the role mouse embryonic stem cell (ESC) differentiation. In our research, we investigated effect on ESC embryoid body (EB) results that overexpression upregulated a set endoderm‐specific gene...
The similar nervous system structure between crustaceans and insects the high-water solubility of thiamethoxam can lead to more severe toxicity crustaceans. However, effects on are unclear. Therefore, a 96-h acute test was performed explore hepatotoxicity neurotoxicity Chinese mitten crab (Eriocheir sinensis) at concentrations 0 µg/L, 150 µg/L 300 µg/L. antioxidant detoxification systems (including phases I II) were significantly activated after exposure juvenile crabs for 24 h in group,...