A5103220114- Nanoplatforms for cancer theranostics
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Nanoparticle-Based Drug Delivery
- Advanced Memory and Neural Computing
- Graphene research and applications
- Cancer, Hypoxia, and Metabolism
- Photodynamic Therapy Research Studies
- Supply Chain and Inventory Management
- Energy, Environment, Economic Growth
- Teaching and Learning Programming
- Quantum and electron transport phenomena
- Jewish and Middle Eastern Studies
- Open Education and E-Learning
- Synthesis and properties of polymers
- Educational Games and Gamification
- Ferroelectric and Negative Capacitance Devices
- 2D Materials and Applications
- Semiconductor Quantum Structures and Devices
- Molecular Sensors and Ion Detection
- Environmental Impact and Sustainability
- Sustainable Supply Chain Management
- Membrane Separation and Gas Transport
- Security and Verification in Computing
- Cybercrime and Law Enforcement Studies
Liaocheng University
2024-2025
Anhui Jianzhu University
2025
East China University of Science and Technology
2024
Shanghai University of Electric Power
2024
Shanghai Jiao Tong University
2001-2023
Gwinnett College
2022-2023
Georgia Gwinnett College
2022-2023
Beijing Technology and Business University
2023
Beijing Institute of Technology
2020-2022
Beijing Haidian Hospital
2022
Cancer cells in hypoxic tumors are remarkably resistant to photodynamic therapy. Here, we hypothesize that an oxygen and Pt(II) self-generating multifunctional nanocomposite could reverse the hypoxia-triggered PDT resistance. The contains Pt(IV) chlorin e6, which upconversion nanoparticles loaded convert 980 nm near-infrared light into 365 660 emissions. Upon accumulation at tumor site, a laser is used trigger generate O2 for consumption process produce cytotoxic reactive species. composite...
Intelligent materials with adaptive response to external stimulation lay foundation integrate functional systems at the material level. Here, experimental observation and numerical simulation, we report a delicate nano-electro-mechanical-opto-system naturally embedded in individual multiwall tungsten disulfide nanotubes, which generates distinct form of in-plane van der Waals sliding ferroelectricity from unique combination superlubricity piezoelectricity. The enables programmable...
Herein, a new three-dimensional Eu-MOF, [Me2NH2]2[Eu3(mtptc)2(CH3COO)3]·DMA·H2O (1), has been elaborately prepared through the reaction of europium nitrate and symmetric tetra-carboxylate ligand, 5′-methyl-[1,1′:3′,1″-triphenyl]-3,3″,5,5″-tetracarboxylic acid (H4mtptc). Noteworthily, compound 1 represents marked stability covering acid–base in pH range 2–14, thermal maintaining skeleton integrity when heated at 350 °C, solvent some common solvents, air open more than 4 weeks characterized by...
A water-blocking polyzwitterion ionic liquid (poly([2-(methacryloyloxy)ethyl]dimethyl-(3-sulfopropyl)- co-tert -butyl) (P(SBMA- co -BuA)) coating is designed on Zn anode as a protective layer. Highly stable batteries are achieved via modified anodes.
Novel ultrasound-responsive polymer vesicles with ultrathin walls and a special packing model were generated from an amphiphilic multiblock copolyamide.
Despite the great advances achieved in hypoxia-associated tumor therapy, efficacy of hypoxia-activated prodrugs alone is usually limited owing to moderate oxygen supply at area. Herein, we develop a polymerized platinum(iv) compound-based nanogel (polyprodrug) containing bioreductive and prodrug (tirapazamine, TPZ) as combo (polyprodrug@TPZ) for synergistic chemotherapy. Upon exposure microenvironment, moieties polyprodrug are reduced platinum(ii) species, which significantly upregulates...
N -Functionalized amino ligand-stabilized ruthenium complexes catalyze the hydrogenation of unsaturated carbonyl derivatives into corresponding alcohols with CC bonds retained under ambient H 2 pressure in water.
In the work, a 3D Zn-based MOF, [CH3(NH2)2][Zn2(obdb)(OH)]·DMF (compound 1) has been formed successfully through self-assembly of Zn(II) ion and organic linker H4obdb (4',4‴-oxybis[1,1'-biphenyl]-3,5-dicarboxylic acid, high-symmetrical tetra-carboxylate ligand) under solvothermal conditions. structure compound 1, Zn symmetry-generated ones constitute tetra-nuclear cluster [Zn4(μ2-COO)8(μ3-OH)2], then by coordination clusters linkers, stair-like framework containing 1D rectangular channel...
Recent years have witnessed significant progress in molecular probes for cancer diagnosis. However, the conventional are designed to be “always‐on” by attachment of tumor‐targeting ligands, which limits their abilities diagnose tumors universally due variations targeting efficiency and complex environment different cancers. Here, it is proposed that a color‐convertible, activatable probe responding universal tumor microenvironment tumor‐specific diagnosis without ligands. Based on hallmark...
Abstract Polymeric drug delivery system termed as “polyprodrug amphiphile” poly(2‐methylacryloyloxyethyl phosphorylcholine)‐ b ‐poly(10‐hydroxy‐camptothecin methacrylate (pMPC‐ ‐pHCPT) is developed for the prolonged‐acting cancer therapy. It obtained by two‐step reversible addition–fragmentation chain transfer polymerization of zwitterionic monomer MPC and an esterase‐responsive polymerizable prodrug methacrylic anhydride–CPT, respectively. This diblock polymer composed both antifouling...
Tourism is linked to multiple dimensions, such as the economy, society, and environment, relationships among its influencing factors are complex, diverse, overlapping. This study constructed an evaluation index system measure degree of coordinated development tourism, transportation, regional then built a tourism-transportation-based Spatial Durbin Model (SDM) regarding process tourism in Beijing-Tianjin-Hebei region (BTHR) from 2010 2020. paper explains current status sustainable BTHR...
Two-dimensional (2D) material solution attracts intense attention from the fields of energy, healthcare, and electronics. Raman spectroscopy is a versatile tool for studying properties 2D materials. Despite numerous elaborate studies solid-state materials, few have focused on solution-phase In this work, we systematically investigated representative MoS2 using angle-resolved polarized spectroscopy, helicity-resolved resonant spectroscopy. With careful analysis, find that spectra feature...
Smart buildings have a large number of dispatchable resources, both for power production and consumption functions, the energy intelligent building clusters has good complementary interactive relationship, which can better promote local distributed energy. In order to realize goal “dual-carbon” construction new system mainly based on renewable energy, this paper takes Business Building (BSB) cluster with photovoltaic (PV) generation as research object. A peer-to-peer (P2P) trading model...
Abstract Geometric diodes, which take advantage of geometric asymmetry to achieve current flow preference, are promising for THz rectification. Previous studies relate diodes’ rectification quantum coherent or ballistic transport, is fragile and critical the high-quality transport system. Here we propose a different physical mechanism demonstrate robust originating from asymmetric bias induced barrier lowering, generally applies common semiconductors in normal environments. Key factors...
Hypoxia-induced multi-drug resistance (MDR) often develops in the chemotherapy process of most anticancer drugs (e.g., doxorubicin, DOX) and results treatment failure clinic. Herein, a PEG-Pt(IV) prodrug was co-self-assembled with DOX into nanodrugs (PEG-Pt(IV)@DOX NPs). They can accumulate tumor sites due to their longer blood retention half-life. Under light irradiation, situ self-generate oxygen (O2) reduce hypoxic zone tissue effectively simultaneously release active cis-Pt(II) DOX. The...
The efficiency of bandwidth scheduling in high-performance networks (HPNs) is critical to the utilization network resources and satisfaction user requests. We consider a periodic problem maximize number satisfied fixed-slot reservation requests, referred as multiple (MFSBS), which shown be NP-complete. first design minimum resource occupation algorithm for special type M-FSBS with identical slots, MinRO-IS, further propose generalized version MinRO arbitrary slots. also four greedy...