A5046942540- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal disorders and treatments
- Gallbladder and Bile Duct Disorders
- IgG4-Related and Inflammatory Diseases
- Phagocytosis and Immune Regulation
- Pediatric Hepatobiliary Diseases and Treatments
- Fibroblast Growth Factor Research
- Metabolism, Diabetes, and Cancer
- MicroRNA in disease regulation
- Liver Disease Diagnosis and Treatment
- Immune cells in cancer
- Child Nutrition and Water Access
- Music Technology and Sound Studies
- Kidney Stones and Urolithiasis Treatments
- Climate Change and Health Impacts
- Colorectal Cancer Screening and Detection
- Spinal Dysraphism and Malformations
- Abdominal Trauma and Injuries
- Diet, Metabolism, and Disease
- Lipid metabolism and disorders
- Cancer, Hypoxia, and Metabolism
- Gastric Cancer Management and Outcomes
- Kruppel-like factors research
- Anorectal Disease Treatments and Outcomes
Yonsei University
2024
Severance Hospital
2024
Second Military Medical University
2014-2022
Changhai Hospital
2014-2022
Shanghai Business School
2022
Stony Brook University
2019-2022
Zhengzhou University
2022
Zhejiang University
2019
Nanjing General Hospital of Nanjing Military Command
2018
SwissLitho (Switzerland)
2016
Diabetes mellitus (DM) is a common complication of chronic pancreatitis (CP) and increases the mortality. The identification risk factors for DM development may contribute to early detection potential reduction in patients with CP. Patients CP admitted Changhai Hospital (Shanghai, China) from January 2000 December 2013 were enrolled. Cumulative rates after onset calculated by Kaplan-Meier method. Risk diagnosis identified Cox proportional hazards regression model. A total 2011 During...
We aimed to investigate outcomes of pancreatic extracorporeal shock wave lithotripsy (P-ESWL) for the removal large stones coexisting with pseudocysts (PPCs) in chronic pancreatitis (CP).This is a prospective study performed CP patients at least 1 stone (≥5 mm). Patients were divided into PPC group (stones PPCs) or control alone). initially subjected successive P-ESWL treatments, followed by ERCP. Primary adverse events, and secondary clearance, long-term pain relief, improved...
Objectives This study aims to evaluate prospectively the safety and efficacy of extracorporeal shock wave lithotripsy (ESWL) in Chinese patients. Methods A total 214 patients with painful chronic pancreatitis pancreatic stones who underwent ESWL followed by endoscopic retrograde cholangiopancreatography from March 2011 February 2012 Changhai Hospital were enrolled. The main duct clearance rate complications recorded prospectively. Symptoms, weight, quality life, function assessed before...
Background Chronic pancreatitis (CP) is a chronic inflammatory disease of the pancreas. This study aimed to compare natural course alcoholic (ACP) and idiopathic (ICP). Methods CP patients admitted our center from January 2000 December 2013 were enrolled. Characteristics compared between ACP ICP patients. Cumulative rates diabetes mellitus (DM), steatorrhea, pancreatic stone, pseudocyst, biliary stricture, cancer after onset diagnosis calculated, respectively. The cumulative DM steatorrhea...
Abstract This study aimed to investigate the occurrence of and determine risk factors for steatorrhea in chronic pancreatitis (CP). It was based on analysis both retrospectively prospectively acquired database CP patients admitted our center from January 2000 December 2013. Demographic data, course disease, medical history follow-up evaluations were documented detail. Cumulative rate calculated by using Kaplan–Meier method. For factor analysis, multivariate Cox proportional hazards...
Abstract Chronic pancreatitis (CP) is an inflammatory disease characterized by progressive fibrosis of pancreas. Early diagnosis will improve the prognosis patients. This study aimed to obtain serum miRNA biomarkers for early CP. In current study, we analyzed differentially expressed miRNAs (DEmiRs) CP patients from Gene Expression Omnibus (GEO), and DEmiRs in plasma (n = 10) clinic microarrays. levels were further tested clinical samples including 20), late 20) healthy controls 18). The...
<b>Background and aims</b> Pancreatic extracorporeal shock wave lithotripsy (P-ESWL) is recommended as the first-line treatment for pancreatic stones. However, how well P-ESWL performs in pediatric patients remains unclear. We aimed to evaluate safety efficacy of with chronic pancreatitis. <b>Methods </b>This prospective observational study was conducted painful pancreatitis who underwent P-ESWL. Patients aged under 18 years were included group; over same period assigned control group. For...
Abstract Background and Aim Pancreatic pseudocyst is a common complication of chronic pancreatitis. The identification risk factors development nomogram for pancreatic pseudocysts in pancreatitis patients may contribute to the early diagnosis intervention pseudocysts. Methods Patients with admitted our center from January 2000 December 2013 were enrolled. Cumulative rates after onset calculated. randomly assigned, 2:1 ratio, training validation cohort. Based on cohort, identified through Cox...
To identify the risk factors and develop nomograms for common bile duct (CBD) stricture in chronic pancreatitis (CP) patients.CBD is a complication CP has variable clinical presentation ranging from asymptomatic to overt jaundice cholangitis.Patients with admitted Changhai Hospital (Shanghai, China) January 2000 December 2013 were enrolled. Cumulative rates of CBD after onset diagnosis calculated. Patients randomly assigned, 2:1 ratio, training validation cohort. On basis cohort, symptomatic...
Oncogenic KRAS plays a vital role in controlling tumor metabolism by enhancing aerobic glycolysis. Obesity driven chronic consumption of high-fat diet (HFD) is major risk factor for oncogenic KRAS-mediated pancreatic ductal adenocarcinoma (PDAC). However, the HFD metabolic reprogramming has been obscure. Here, using genetically engineered mouse models expressing an endogenous level KRASG12D acinar cells, we demonstrate that hyperactivation obesogenic HFD, as compared to carbohydrate-rich...
The objective of this study was to evaluate the safety and efficacy pancreatic extracorporeal shock wave lithotripsy (P-ESWL) in chronic pancreatitis (CP) patients with stones after previous surgery.This is a single-center prospectively conducted pained CP undergoing P-ESWL. Patients surgery history (PSH) were included PSH group, without during same period assigned control group. primary outcomes complications associated P-ESWL pain relief. Secondary stone clearance improved quality-of-life...
Pediatric patients always suffer from chronic pancreatitis (CP), especially those with steatorrhea. This study aimed to identify the incidence of and risk factors for steatorrhea in pediatric CP. To our best knowledge, there is no document natural history CP.CP admitted center January 2000 December 2013 were enrolled. Patients assigned (< 18 years old) adult group according their age at onset Cumulative rates both groups calculated. Risk identified, respectively.The median follow-up duration...
Background: Pancreatic stones are pathognomonic of chronic pancreatitis (CP). This study aimed to determine the incidence, identify risk factors, and develop a nomogram for pancreatic in CP patients. Methods: Patients with admitted our center from January 2000 December 2013 were enrolled. Cumulative rates after onset diagnosis calculated. randomly assigned, 2:1 ratio, training validation cohort. Based on cohort, factors identified through Cox proportional hazards regression model, was...
Various media information in life can have an important impact on our understanding of music. In this paper, we present a demo, Mind Band, which is Cross-Media artificial intelligent composing platform using elements such as emoji, image and humming. practice, base system the valence-arousal model. We use emotion analysis to map them music pieces, are generated by Variational Autoencoder - Generative Adversarial Networks provide users with immersive experience uploading emoji/image/humming...
KRAS mutations are prevalent in patients with pancreatic ductal adenocarcinoma (PDAC) and critical to fostering tumor growth part by aberrantly rewiring glucose, amino acid, lipid metabolism. Obesity is a modifiable risk factor for cancer. Corroborating this epidemiological observation, mice harboring mutant highly vulnerable obesogenic high-fat diet (HFD) challenges leading the development of PDAC high penetrance. However, contributions other macronutrient diets, such as diets rich...
Respiratory disease remains one of the leading causes morbidity and mortality in China. However, little is known about research status respirology three major regions China-Mainland (ML), Hong Kong (HK) Taiwan (TW). A 10-year survey literature was conducted to compare regions' outputs respirology.A bibliometric study.China.A search PubMed database, updated as September 2012, led identification related articles from 2000 2009. The number total articles, randomised controlled trials, case...
Objectives The aim of this study was to establish a standard describe the spatial distribution pancreatic stones in chronic pancreatitis (CP). Methods Two hundred forty-seven CP patients with from June December 2012 were enrolled. Two-dimensional images coronal projection 3-dimensional computed tomography gained. number (n) all and geometric deviation (σ) distances between centroid centroids every stone that represented nonuniformity calculated by Stone Reconstruction Identification...
Abstract Oncogenic RAS is a critical driver for the initiation and progression of several types cancers. However, effective therapeutic strategies by targeting RAS, in particular G12D G12V , associated downstream pathways have been so far unsuccessful. Treatment oncogenic RAS-ravaged cancer patients remains currently unmet clinical need. Consistent with major role metabolism, activation elevates both reactive oxygen species (ROS)-generating NADPH oxidase (NOX) activity ROS-scavenging...
Objective The pathogenesis of chronic pancreatitis (CP) is not completely clear. With further studies, smoking toxic to the pancreas. This study classified smoking-related CP as a new etiology and defined cutoff smoking. Design Patients with admitted from January 2000 December 2013 were included in study. characteristics compared between patients, drinking group patients who never smoke or drink (control group). cumulative rates steatorrhea, diabetes mellitus (DM), pancreatic pseudocyst...