A5066484602- Refrigeration and Air Conditioning Technologies
- Nanoplatforms for cancer theranostics
- Extracellular vesicles in disease
- Solar-Powered Water Purification Methods
- Adsorption and Cooling Systems
- Membrane Separation Technologies
- Advanced machining processes and optimization
- MicroRNA in disease regulation
- Advanced Manufacturing and Logistics Optimization
- Advanced Surface Polishing Techniques
- Scheduling and Optimization Algorithms
- Heat Transfer and Optimization
- Photoacoustic and Ultrasonic Imaging
- Advanced Thermodynamic Systems and Engines
- Thermal properties of materials
- Melanoma and MAPK Pathways
- Photodynamic Therapy Research Studies
- Sustainable Building Design and Assessment
- Wastewater Treatment and Reuse
- Semiconductor materials and devices
- Marine Biology and Environmental Chemistry
- Construction Project Management and Performance
- Assembly Line Balancing Optimization
- Optimization and Packing Problems
- High-Temperature Coating Behaviors
Huazhong University of Science and Technology
2019-2025
State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing
2022-2025
Union Hospital
2023-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Chongqing Medical University
2022-2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2022-2024
Hong Kong Polytechnic University
2023
Shenzhen University
2023
Union Hospital
2021-2022
Hubei Normal University
2016-2022
Abstract Background Tumor cell-derived exosomes (TEx) have emerged as promising nanocarriers for drug delivery. Noninvasive multimodality imaging tracing the in vivo trafficking of TEx may accelerate their clinical translation. In this study, we developed a TEx-based nanoprobe via hydrophobic insertion mechanism and evaluated its performance dual single-photon emission computed tomography (SPECT) near-infrared fluorescence (NIRF) colon cancer. Results were successfully isolated from HCT116...
Colon cancer contributes to high mortality rates as the result of incomplete resection in tumor surgery. Multimodal imaging can provide preoperative evaluation and intraoperative image-guiding. As biocompatible nanocarriers, extracellular vesicles hold great promise for multimodal imaging. In this study, we aim synthesized an vesicles-based nanoprobe visualize colon with positron-emission tomography/computed tomography (PET/CT) near-infrared fluorescence (NIRF) imaging, investigated its...
Abstract Background Cancer stem cells (CSCs) are crucial for the growth, metastasis, drug resistance, recurrence, and spread of tumors. Napabucasin (NAP) could effectively inhibit CSC, but its mechanism has not been fully explained. Additionally, NAP also drawbacks poor water solubility low utilization. Therefore, this study only elaborated new inhibiting CSCs, built NAP-loaded nanoprobes using apoptotic tumor-derived microparticles (TMPs) as carriers to combine diagnose treat colon cancer...
Abstract Background Photodynamic therapy (PDT) is a promising antitumor strategy with fewer adverse effects and higher selectivity than conventional therapies. Recently, series of reports have suggested that PDT induced by Cerenkov radiation (CR) (CR-PDT) has deeper tissue penetration traditional PDT; however, the coupling radionuclides photosensitizers may cause severe side effects. Methods We designed tumor-targeting nanoparticles ( 131 I-EM@ALA) loading 5-aminolevulinic acid (ALA) into an...
Multimodal image-guided photothermal therapy (PTT) has great application potential in cancer treatment due to its advantages of low side effects and good efficacy. There is an urgent need for PTT nanocarriers with high loading efficiency modified surfaces. Goat milk-derived extracellular vesicles (GMVs) ideal nanoplatforms their anti-inflammatory ability, tumor retention yield, biosafety. This study used GMVs design a theranostic nanoprobe positron emission tomography/computer...
Ischemic stroke, one of the most universal causes human mortality and morbidity, is pathologically characterized by inflammatory cascade, especially during progression ischemia/reperfusion (I/R) injury. F-Box Protein 3 (FBXO3), a substrate-recognition subunit SKP1-cullin 1-F-box protein (SCF) E3 ligase complexes, has recently been proven to be severed as an underlying pro-inflammatory factor in pathological processes diverse diseases. Given these considerations, current study aims at...
In order to better provide a theoretical basis for the machining of luxury vinyl tiles, helical milling experiment was conducted by using diamond cutting tools, and special attention given trends force surface roughness in respect tool geometry parameters. The results showed that resultant negatively correlated helix angle speed, but positively with depth. Then, increased decrease an increase depth, while as speed raised, first declined then increased. Thirdly, depth shown have greatest...
The No-wait Flowshop Scheduling Problem (NWFSP) has always been a research hotspot because of its importance in various industries. This paper uses matheuristic approach that combines exact and heuristic algorithms to solve it with the objective minimize makespan. Firstly, according symmetry characteristics NWFSP, local search method is designed, where first job last symmetrical position remain unchanged, then, three-level neighborhood division corresponding rapid evaluation at each level...
Abstract Chrysotile asbestos has excellent physical and chemical properties, but its high biotoxicity is very damaging to human health, due durability, aspect ratio, the exist of iron. By simple treatment chrysotile asbestos, silicon oxide nanofibers rich in hydroxyl groups on surface can be prepared. In this study, we synthesized a series polyurethane/silicon nano-composite coatings with special performance following blending method that introduced into polyurethane. Measurement results...