A5100698673- Monoclonal and Polyclonal Antibodies Research
- Reproductive System and Pregnancy
- Biosensors and Analytical Detection
- Mitochondrial Function and Pathology
- Photosynthetic Processes and Mechanisms
- Diabetes and associated disorders
- Ferroptosis and cancer prognosis
- Plant Genetic and Mutation Studies
- Innovative Microfluidic and Catalytic Techniques Innovation
- RNA modifications and cancer
- Cancer, Hypoxia, and Metabolism
- Epigenetics and DNA Methylation
- Heme Oxygenase-1 and Carbon Monoxide
- Redox biology and oxidative stress
- Cardiac Valve Diseases and Treatments
- Angiogenesis and VEGF in Cancer
- Folate and B Vitamins Research
- High Altitude and Hypoxia
- Connective tissue disorders research
- Genomics, phytochemicals, and oxidative stress
- T-cell and B-cell Immunology
- NF-κB Signaling Pathways
- Gut microbiota and health
- Genetic Syndromes and Imprinting
- Ectopic Pregnancy Diagnosis and Management
Huazhong Agricultural University
2024-2025
Chinese Academy of Sciences
2011-2025
Suzhou Institute of Nano-tech and Nano-bionics
2025
Second Affiliated Hospital of Nanchang University
2024
Nanjing Agricultural University
2024
Dalian Medical University
2024
Dalian University
2024
University of California, Riverside
2024
Nanchang University
2024
Wenzhou Municipal Sci-Tech Bureau
2024
TNF receptor (TNFR)-associated factor TRAF6 is a key activator of NF-κB, playing critical role in the regulation innate immune responses and their connection to adaptive responses. interactions determine receptor-induced cell death versus survival. has been implicated cancer but its contributions have not investigated deeply. In this study, we show that upregulates expression hypoxia-inducible (HIF)-1α. affects HIF-1α protein levels little effect on mRNA level. increases independent oxygen....
Baicalin, the main active ingredient of Scutellaria root, exerts anti-oxidant and anti-apoptotic effects in cardiovascular diseases. However, therapeutic mechanism baicalin remains unknown. Cultured neonatal rat cardiomyocytes were pre-treated with (0–50 µM) for 24 h, subsequently treated tunicamycin (100 ng/ml). Cell viability was detected by MTT assay, cell damage determined LDH release TUNEL assay. The expression CHOP, JNK, caspase-3, eNOS analyzed western blot. NO measured DAF-FM...
China's National Essential Public Health Service Package (NEPHSP) aims to promote health for all at the primary care level and includes a focus on hypertension type-2 diabetes mellitus (T2DM). However, there are limited contemporary data quantify cascades of T2DM in care.
To analyze the characteristics of oral microbiota in plateau and plain youth possible function microbiome.A total 120 healthy young males (80 on plateau, 40 plain) completed this cross-sectional study. Oral microflora samples were collected from all participants. The bacterial 16S rDNA was amplified using PCR sequenced Illumina MiSeq high-throughput sequencing. data analyzed to determine microbial distribution community structure two groups. Metastats used test differences relative species...
This study investigates the molecular mechanisms of CC@AC&SF@PP NPs loaded with AC099850.3 siRNA and sorafenib (SF) for improving hepatitis B virus-related hepatocellular carcinoma (HBV-HCC). A dataset 44 HBV-HCC patients their survival information was selected from TCGA database. Immune genes related to status were identified using ImmPort database WGCNA analysis. prognostic risk model constructed analyzed Lasso regression. Differential analysis performed screen key genes, significance...
Objectives This study aimed to assess the association between plasma glutamate (Glu) and risk of cardiovascular disease (CVD) in patients with type 2 diabetes mellitus (T2DM) whether this differs by gender. Material methods We retrieved clinical information on 1032 consecutive T2DM from a same tertiary care center May 2015 August 2016. Glu was quantified liquid chromatography-tandem mass spectrometry analysis. converted into categorical variable based median concentration whole population,...
Background Abnormal intracellular glucose/fatty acid metabolism of T cells has tremendous effects on their immuno-modulatory function, which is related to the pathogenesis autoimmune diseases. However, association between status and type 1 diabetes unclear. This study aimed investigate uptake glucose fatty acids in its relationship with disease progression diabetes. Methods A total 86 individuals were recruited detect cells. 2-NBDG expression transporter (GLUT1); or BODIPY carnitine...
PurposeTo investigate the therapeutic efficacy of BAR in abortion-prone mice and explore potential mechanisms regarding MDSCs.MethodsRSA (CBA/J females paired with BALB/c males) were administered BAR1 (5.7 g/kg), BAR2 (11.4 progesterone (P4), or distilled water from embryo day (D) 0.5 until D10.5. The absorption rate on D10.5 progeny health status measured. Systemic inflammatory states placenta-uterus milieu assessed by serum cytokine levels architectures as well relative protein mRNA...
Objective: The objective of this study was to investigate the regulation relationship Teneleven translocation 1 (<i>Tet1</i>) in DNA demethylation and proliferation primordial germ cells (PGCs) chickens.Methods: siRNA targeting <i>Tet1</i> used transiently knockdown expression chicken PGCs, genomic methylation status measured. PGCs detected by flow cytometry analysis cell counting kit-8 assay when activation or inhibition Wnt4/β-catenin signaling pathway. And level...
The objective of this study was to identify candidate genes that play important roles in skeletal muscle development ducks.