A5046603042- Antibiotic Use and Resistance
- Microscopic Colitis
- Celiac Disease Research and Management
- Inflammatory Bowel Disease
- Child and Adolescent Health
- Antibiotics Pharmacokinetics and Efficacy
- Pneumonia and Respiratory Infections
- Eosinophilic Esophagitis
- Patient Satisfaction in Healthcare
- Antibiotic Resistance in Bacteria
- Human Health and Disease
- Digestive system and related health
- Environmental Science and Water Management
- Gastrointestinal disorders and treatments
- Adolescent and Pediatric Healthcare
- Pediatric Pain Management Techniques
- Nutrition, Genetics, and Disease
- Child Nutrition and Feeding Issues
- Gastrointestinal motility and disorders
- Growth Hormone and Insulin-like Growth Factors
- Respiratory and Cough-Related Research
- Pancreatitis Pathology and Treatment
- Pharmaceutical studies and practices
- Intestinal Malrotation and Obstruction Disorders
- Pregnancy and Medication Impact
University Hospital Centre Zagreb
2018-2025
University of Rijeka
2010-2025
Klinički Bolnički Centar Rijeka
2008-2024
Klinika za psihijatriju Vrapče
2018-2024
Children's Hospital Zagreb
2024
Children's Hospital Srebrnjak
2021
IRCCS Materno Infantile Burlo Garofolo
2020
Harvard University
2017
Harvard University Press
2017
Boston Children's Hospital
2011
During the past decades, there has been a shift in clinical presentation of coeliac disease (CD) to nonclassical, oligosymptomatic, and asymptomatic forms. We assessed CD children adolescents Central Europe.Paediatric gastroenterologists 5 countries retrospectively reported data their patients diagnosed with CD. Clinical was analyzed differences among very young (<3 years) older were studied.Data from 653 (median age 7 years 2 months; 63.9% girls) Croatia, Germany, Hungary, Italy, Slovenia...
Celiac disease (CD) is an autoimmune triggered by gluten in genetically predisposed individuals. Despite the increasing prevalence of CD, many patients remain undiagnosed. Standard serology tests are expensive and invasive, so several point-of-care (POC) for CD have been developed. We aimed to determine first-grade pupils Primorje-Gorski Kotar County, Croatia, using a POC test.A Biocard celiac test that detects IgA antibodies tissue transglutaminase whole blood was used screen healthy...
Coeliac disease (CD) is a systemic autoimmune disorder affecting about 1% of the population. Many patients remain undiagnosed or are diagnosed with substantial delay. We assessed diagnostic delays in symptomatic CD children Central Europe (CE).Paediatric gastroenterologists 5 CE countries retrospectively reported data their 2016. Age at first CD-related symptom(s), visit to paediatric gastroenterologist and confirmed diagnosis were used determine delays.Data from 393 (65% girls, median age 7...
Background: Crohn’s disease (CD) is a chronic inflammatory condition that can affect the gastrointestinal tract and cause significant extraintestinal manifestations. Diagnosing monitoring activity, especially in pediatric patients, remains challenge due to variable clinical presentations limitations of traditional imaging methods. Objective: This study aimed evaluate compare diagnostic accuracy utility small bowel capsule endoscopy (SBCE) versus magnetic resonance enterography (MRE) for...
ABSTRACT Objectives: Celiac disease (CD) remains undiagnosed for a long time in many adult and pediatric patients. We assessed the knowledge about CD among healthcare professionals (HCPs) patients Central Europe (CE). Methods: HCPs from 5 CE countries were asked to complete web‐based questionnaire CD. The questions divided into subsections on epidemiology, clinical presentation, diagnostics, treatment, follow‐up. Achieved scores of different specialists managing with compared regional...
Abstract Purpose In this study, we evaluated antibiotic utilisation pattern at two paediatric clinics in different European (transitional) countries: Croatia (Rijeka) and Russia (Smolensk). Methods Antibiotic during the year 2000 was observed using ATC/defined daily doses (DDD) methodology (ATC code‐J01). Drug‐usage data expressed numbers of DDD/100 bed‐days DU90% profile. Results Rijeka, 35 systemic antibiotics were used Smolensk 22. The overall consumption drugs Rijeka more than three...
The current European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) guidelines introduced the option to diagnose coeliac disease (CD) in children adolescents without upper endoscopy if defined criteria are met. aim of our study was evaluate how frequently paediatric gastroenterologists Central Europe used "no-biopsy" approach often duodenal biopsy could have been omitted. Medical records patients aged < 19 years diagnosed with CD 2016 from five countries were...
To evaluate the quality of antimicrobial drug use in a university hospital medical department (Department Medicine, University Hospital Rijeka, Croatia) with 279 hospital-beds wards containing patients from endocrinology, gastroenterology, hematology, clinical immunology, cardiology and coronary care unit, nephrology pulmonology sections hospital.The appropriateness treatment for all in-patients Department Medicine was assessed prospective, longitudinal survey carried out during 21-week...
Purpose To compare the utilisation of systemic antimicrobials at paediatric units university hospitals in Marburg (Germany) and Rijeka (Croatia). Methods A prospective, observational analysis hospital records from 300 incident users each study centre that were younger than 19 years. Antimicrobial was analysed six gender-specific age groups with respect to drug choice, duration treatment stay, indication route administration. The extent antimicrobial use assessed by number courses. Results In...
Hereditary spherocytosis is the most frequent congenital hemolytic anemia and characterized with variable degree of anemia, jaundice, splenomegaly. In case severe hyperbilirubinemia out proportion hemolysis, other causes must be considered. Gilbert syndrome (GS) an autosomal dominant disorder intermittent without any sign symptom liver disease as a result reduced activity uridine diphosphate-glucuronyl transferase 1A1. The calculated rate coexistence these 2 diseases 15 to 35/million births....
The aim of this study was to determine the annual incidence and geographic distribution pediatric inflammatory bowel disease (IBD) in Croatia. This is a prospective, cohort, multicenter observational based on data obtained from Croatian national registry for children with IBD. Children adolescents younger than 18 years diagnosed IBD, time period between June 1, 2016, May 31, 2017, were recruited. In total, 51 new cases identified; 19 Crohn’s disease, 28 ulcerative colitis, 8...
To analyse the consumption rate of new generation antiepileptic drugs (AEDs) compared with traditional AEDs at a university hospital in Croatia. Antiepileptic use was analysed retrospectively for two consecutive years, 2001 and 2002 Departments Neurology, Paediatrics, Psychiatry Neurosurgery University Hospital Centre (UHC) Rijeka. The results obtained are expressed as number defined daily doses (DDDs) per 100 bed days, proposed by WHO. represented 2% 5% 2002. Majority administered taken...
To evaluate the quality of antimicrobial drug prescribing at a university hospital in Department Medicine, by using new scoring system as indicator.a prospective, longitudinal survey, during 21-week period. The necessity treatment all in-patients to whom antimicrobials were prescribed, was assessed based on presence signs and symptoms an infection. If sum's total score 3 or more, deemed justifiable; if less than 3, regarded questionable.Department Medicine (279 hospital-beds) University...
Abstract Purpose In this study, the extent and pattern of inpatient outpatient antimicrobial drug use was investigated in Rijeka, Croatia, impact control measures evaluated. Methods Consumption antibacterials for years 2000 2001 monitored using ATC/DDD methodology. Results During investigation period, utilization at University Hospital Center (UHC) Rijeka has decreased by 14%. setting County Primorje Gorski kotar, similar during both years. At UHC not only amount, but antibacterial also...
Recently published paediatric guidelines for diagnosing coeliac disease do not include recommendations on the follow-up of patients.The aim this study was to assess management practices and experience patients with their appointments in Central Europe.Gastroenterologists five European countries were asked complete web-based questionnaire focusing practices.Answers from 147 gastroenterologists 2041 available analysis. More than half (58.5%) schedule first visit within 3 months after...
Edema is defi ned as abnormal accumulation of fl uid in the interstitium. Differential diagnosis generalized edema very broad. Most often, renal and cardiac causes lead to edema. The potential gastrointestinal are liver failure protein losing enteropathy including celiac disease malnutrition. Generalized rarely an initial manifestat ion disease. Hereby, we present a case 3-year-old boy with disease, initially presented hypoproteinemia.
Cilj: Prikazati jedanaestogodišnjeg bolesnika sa šećernom bolešću tipa 2 s ciljem podizanja svijesti o porastu incidencije šećerne bolesti u pedijatrijskoj populaciji. Prikaz slučaja: Tijekom neurološke obrade devetogodišnjeg dječaka ustanovljeno je da dječak preuhranjen i ima akantozu na vratu. Laboratorijskim pretragama utvrđeni su povišeni jetreni enzimi, a ultrazvučnim pregledom abdomena difuzno ehogenija jetra homogenih odjeka. Iz obiteljske anamneze saznalo se oba roditelja boluju od...