<h3>Abstract</h3> <b>Objectives:</b> To investigate the association between duration of exclusive breast feeding and development asthma related outcomes in children at age 6 years. <b>Design:</b> Prospective cohort study. <b>Setting:</b> Western Australia. <b>Subjects:</b> 2187 ascertained through antenatal clinics major tertiary obstetric hospital Perth followed to <b>Main outcome measures:</b> Unconditional logistic regression model or atopy years age, allowing for several important...

A randomly selected group of 331 children who had started to wheeze in childhood and a control 77 were prospectively studied clinically physiologically from 7 21 years age. Most subjects improved during adolescence about 55% those whose wheezing before stopped remained free. Forty-five per cent apparently ceased at 14 minor recurrences between Fewer than 20% with persistent symptoms become totally free adolescence, although there was amelioration symptoms. Girls did less well boys, so that...

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The relationship between reduced pulmonary function in early life and persistent wheeze (PW) school-aged children remains uncertain. In this study, VmaxFRC was assessed at 1 month of age, the presence up to 11 years age prospectively identified. At airway responsiveness (AR) inhaled histamine atopy were assessed. Recent associated with a mean z score for (-0.41 [SD 0.91], n = 31) compared no recent (0.04 1.00], 153, p 0.03). Wheeze 4 6 that persisted most prevalent among those aged (p 0.002)...

Maximal flows at functional residual capacity (VmaxFRC) from partial expiratory flow-volume (PEFV) curves (achieved with rapid compression of the chest) were obtained on 11 healthy newborn babies. Mean VmaxFRC, size corrected by dividing absolute values measured thoracic gas volume, was 1.90 TGV's/s. Specific upstream conductances high, and cross-sectional area flow-limiting segment estimated to be approximately 0.30 cm2 in three infants whom recoil pressures FRC also measured. The major...

Acute viral respiratory illness during infancy has been implicated as a precursor for subsequent lower morbidity in childhood. A prospective, longitudinal study of function, airway responsiveness, and early childhood was performed cohort 253 healthy infants to characterise those who experienced bronchiolitis. Seventeen (7% the cohort), were given diagnosis bronchiolitis first two years life with (1%) requiring hospital admission. Seventy one per cent had family history atopy, 53% asthma, 29%...

1: Lung Growth and Development . 2: Neonatal Respiratory Disorders 3: Epidemiology of Acute Infections 4: Clinical Patterns Infection 5: Noises 6: Asthma - Pathogenesis, Pathophysiology 7: Management 8: Cough 9: Suppurative Disease 10: Cystic Fibrosis 11: Pulmonary Complications Inhalation 12: Tuberculosis in Childhood 13: Defences the Compromised Host 14: The HIV 15: Miscellaneous Diseases 16: Obstructive Sleep Apnoea 17: Congenital Malformations Bronchi, Lungs, Diaphragm Rib Cage 18:...

Cough is a common and distressing symptom that results in significant health care costs from medical consultations medication use. reflex activity with elements of voluntary control forms part the somatosensory system involving visceral sensation, motor response associated behavioural responses. At initial assessment for chronic cough, clinician should elicit any alarm symptoms might indicate serious underlying disease identify whether there specific present cough. If examination, chest...

The goals of this study were to: (1) determine if management according to a standardized clinical pathway/algorithm (compared with usual treatment) improves outcomes by 6 weeks; and (2) assess the reliability validity pathway for chronic cough in children.A total 272 children (mean ± SD age: 4.5 3.7 years) enrolled pragmatic, multicenter, randomized controlled trial 5 Australian centers. Children randomly allocated 1 2 arms: early review use algorithm ("early-arm"); or care until...

Summary The aim of this study was to examine prospectively the relation between duration breast feeding and cognitive outcomes. A cohort 2860 children enrolled before birth provided data from 2393 term infants English‐speaking mothers. Of these, complete infant in first year life verbal IQ (Peabody Picture Vocabulary Test – PPVT‐R) were available for 1450 at 6 years, a performance subtest (Perceptual organisation WISC Block Design) 1375 8 years. Full categorised as none,&gt; 0 &lt; 4 months,...

Reports have suggested that certain infants are predisposed to wheezing in the first 2 yrs of life due abnormal lung function, prior illness. The authors investigated association between infant function and wheeze during life. A cohort 253 was evaluated. Respiratory assessment performed at 1, 6, 12 months age. Parental history asthma, atopy, maternal antenatal smoking habits were recorded. An identified as having wheezed on basis parental report and, where possible, physician diagnosis. One...

Abstract From a cohort of 543 healthy children and adolescents, subjects were studied annually to obtain longitudinal data so that precise predictive values for lung volumes flows from ages 8 19 years could be obtained. Strict guidelines subject selection pulmonary function testing used. These are presented in readily usable form as equations, graphs, tables. Pediatr Pilmonol. 1989; 7:101–109 .

We investigated the relationship between breastfeeding, asthma and atopy, child body mass index (BMI).

Pulmonary function was measured in 277 subjects at 21 yr of age who had wheezed before the 7 yr, and a control group that been followed prospectively for 14 yr. The wheezing covered whole spectrum childhood asthma. Subjects minor wheeze wheeze-free least 3 were, as group, indistinguishable from group. There an increasing incidence abnormality with frequency wheezing. chronic asthma large vital capacity relative to body size age, but this no longer present age. Bronchial lability exercise not...

Inhaled sympathomimetic agents are often used in bronchiolitis with little objective evidence of benefit. The arterial oxygen saturation (SaO2) reflects the adequacy ventilation-perfusion balance. aim current study was to determine effect inhaled salbutamol on SaO2. In a randomised, double blind study, 21 infants, admitted positive for respiratory syncytial virus, had continuous SaO2 measurements made before and after nebulised or placebo. recorded over 30 minutes baseline, then during 10...

Consensus recommendations for managing chronic suppurative lung disease (CSLD) and bronchiectasis, based on systematic reviews, were developed Australian New Zealand children adults during a multidisciplinary workshop. The diagnosis of bronchiectasis requires high-resolution computed tomography scan the chest. People with symptoms but non-diagnostic scans, have CSLD, which may progress to radiological bronchiectasis. CSLD/bronchiectasis is suspected when wet cough persists beyond 8 weeks....

The age at which nonspecific bronchiai hyperresponsiveness (BHR) is first seen in humans unknown, though both genetic and environmental factors have been implicated its development. current study aimed to establish whether BHR histamine can be demonstrated normal infants. Twelve infants, mean of 7.8 months (range, 3 18 months), were studied. None had any history a previous significant respiratory illness. Respiratory function was monitored using the maximal flow residual capacity (maxFRC)...

Although most wheezy infants are considered asthmatic, they generally respond poorly to antiasthma treatment, and there is inadequate knowledge about the pathologic mechanisms that cause wheezing at this age. The aim of study was determine whether strong association between bronchial responsiveness (BR) seen in older subjects also present infants. We compared BR with inhaled histamine 19 recurrently a group age-, height-, weight-, sex-matched control Maximal flow FRC (VmaxFRC) determined...

Seventeen boys and 19 girls, 8–15 yr in age, were studied to ascertain, the two sex groups, predictors of airway size [assessed by measurement tracheal cross-sectional area (CSA) maximal expiratory flows (Vmax)] relative rates growth major divisions airways lung parenchyma. In boys, total capacity (TLC) accounted for 77% variance CSA 66% variability Vmax. contrast, somatic maturation girls only 45% 64% Vmax; TLC was relatively unimportant. but not TLC-corrected significantly inversely...

In light of the obesity epidemic, we aimed to characterize novel childhood adiposity trajectories from birth age 14 years and determine their relation adolescent insulin resistance.A total 1,197 Australian children with cardiovascular/metabolic profiling at were studied serially years. Semiparametric mixture modeling was applied anthropometric data over eight time points generate z scores (weight-for-height BMI). Fasting homeostasis model assessment resistance (HOMA-IR) compared between...

Many asthmatic patients demonstrate bronchial lability with a six-minute period of exercise, which is characterised by an initial bronchodilatation followed bronchoconstriction. This early response has been further analysed investigation the effects repeated 30-second sprints before and after run. It was found that these short did not induce bronchoconstriction, resulted in less bronchoconstriction subsequent run, caused if exercise-induced present. postulated this effect may be related to...