A5064249052- Nanoplatforms for cancer theranostics
- Ammonia Synthesis and Nitrogen Reduction
- CRISPR and Genetic Engineering
- Advanced Nanomaterials in Catalysis
- RNA Interference and Gene Delivery
- Hydrogen Storage and Materials
- Cancer Research and Treatments
- Caching and Content Delivery
- Ga2O3 and related materials
- Cancer, Hypoxia, and Metabolism
- E-commerce and Technology Innovations
- Comparative and International Law Studies
- Power Systems and Technologies
- Conflict of Laws and Jurisdiction
- 3D Printing in Biomedical Research
- Internet of Things and Social Network Interactions
- Microbial Fuel Cells and Bioremediation
- Mathematical Biology Tumor Growth
- European and International Law Studies
- Image Processing and 3D Reconstruction
- Hand Gesture Recognition Systems
- Cancer, Lipids, and Metabolism
- Cancer Genomics and Diagnostics
- bioluminescence and chemiluminescence research
- Prostate Cancer Treatment and Research
Nanjing University of Chinese Medicine
2021-2024
Fudan University
2022-2023
Nanjing Medical University
2023
Jiangsu Province Hospital
2023
Dalian University of Technology
2022
Xi'an Jiaotong University
2021
Manipulation of CRISPR delivery for stimuli-responsive gene editing is crucial cancer therapeutics through maximizing efficacy and minimizing side-effects. However, realizing controlled synergistic combination therapy remains a key challenge. Here, near-infrared (NIR) light-triggered thermo-responsive copper sulfide (CuS) multifunctional nanotherapeutic platform constructed to achieve release CRISPR-Cas9 ribonucleoprotein (RNP) doxorubicin tumor involving in therapy, mild-photothermal (PTT),...
Targeting androgen receptor (AR) has shown great therapeutic potential in triple-negative breast cancer (TNBC), yet its efficacy remains unsatisfactory. Here, we aimed to identify promising targeted agents that synergize with enzalutamide, a second-generation AR inhibitor, TNBC. By using strategy for screening drug combinations based on the Sensitivity Index (SI), found MK-8776, selective checkpoint kinase1 (CHK1) showed favorable synergism enzalutamide AR-positive The combination of and...
Near-infrared (NIR)-light-triggered nanomedicine, including photodynamic therapy (PDT) and photothermal (PTT), is growing an attractive approach for cancer due to its high spatiotemporal controllability minimal invasion, but the tumor eradication limited by intrinsic anti-stress response of cells. Herein, we fabricate a tumor-microenvironment responsive CRISPR nanoplatform based on oxygen-deficient titania (TiO
Hepatic stellate cells (HSCs) represent a significant component of hepatocellular carcinoma (HCC) microenvironments which play critical role in tumor progression and drug resistance. Tumor-on-a-chip technology has provided powerful vitro platform to investigate the crosstalk between activated HSCs HCC by mimicking physiological architecture with precise spatiotemporal control. Here we developed tri-cell culture microfluidic chip evaluate impact on progression. On-chip analysis revealed...
Circulating tumor cell clusters/micro-emboli (CTM) possess greater metastatic capacity and survival advantage compared to individual circulating (CTC). However, the formation of CTM subtypes their role in metastasis remain unclear. In this study, we used a microfluidic Cluster-Chip with easy operation high efficiency isolate from peripheral blood, which confirmed correlation clinicopathological features identified critical CTC-platelet clusters breast cancer metastasis. The between platelets...
Electrochemistry is a potential technology to remove nitrate from high-salinity water. Due electrostatic repulsion of cathodes NO3¯ anions, will be pushed anodes thus limiting the reduction reaction at cathodes. To restrain repulsion, an alkali-etched microchannel charcoal (AEMC) was fabricated as cathode. Its channel radius less than 10 μm but length more 4 cm. The function alkali etching create oxygen-containing groups active site. During reaction, anions can flow through cathodic with...
Abstract Cancer treatment by inducing tumor cell immunogenic death (ICD) is critical for therapy. However, ICD activation single pathway often limited in practical application due to its low efficiency. In addition, the pH and anoxic microenvironments solid tumors greatly limit effective of ICD. Herein, hollow manganese dioxide (H-MnO 2 ) nanomaterials were selected load both Mitoxantrone (MTZ) Chlorin e6 (Ce6) structure ability release drugs acidic environments. Thus, synergy photodynamic...
The aim of the paper is to offer advice about setting on investigating feasibility a legal system reciprocal recognition civil case jurisdiction among East Asia region. present conditions for foreign in states are whole similar and this an advantage construction unified mechanism. This gives three selected models jurisdiction, which bilateral judicial assistance treaty, regional multilateral treaties soften principle reciprocity.
Synergistic Therapy In article number 2101155, Yujun Song, Zhengbao Zha, Xin Han, and co-workers report a novel thermo-responsive nanotherapeutic platform, which is triggered by 808 nm near-infrared light irradiation. This exogenously controlled method can be used in combination tumor therapy, including gene-therapy, mild-photothermal chemotherapy, provides versatile strategy for gene editing drug release synergistic therapy with maximizing efficacy minimizing side-effects.
Wireless communication devices are commonly used in rowing training assistance systems, but there is disconnection caused by human occlusion during use. In order to verify the impact of and explore a more optimal deployment method, it has guiding significance system applications use mathematical physical methods simulate attenuation signal strength occlusion. This article selects 2.4G frequency simulates wireless transmission multipath reflection on boat under multi-person interference...
Abstract: In order to improve the athletic performance of rowers in China, this paper proposes a comprehensive design an intelligent propeller pool digitization system based on multisource data fusion. The current level is low, lacking overall consistency research and development, heavily relying subjective judgments from coaches for evaluation. By focusing real-time collection key parameters such as internal load, rowing force, trajectory, well analysis historical data, facilitates...
The intelligent communication network of substation often adopts the form wired communication. Due to its many disadvantages such as complicated lines and partial discharge interference, deployment wireless has become focus scene research. It is great significance in industrial construction carry out signal simulation by using electromagnetic method guide scheme hardware module according data results. Taking 433M band an example, this paper uses FEKO software simulate transmission multipath...
Abstract Cancer treatment by inducing tumor cell immunogenic death (ICD) is a hot research direction. However, ICD activation single pathway often limited in practical application due to its low efficiency. In addition, the pH and anoxic environment which solid tumors occur also greatly limit effective of ICD. Herein, hollow manganese dioxide (H-MnO 2 ) nanomaterials were selected load both Mitoxantrone (MTZ) Chlorin e6 (Ce6) structure ability release drugs acidic environment. Thus, synergy...