A5078135828- Mesenchymal stem cell research
- Adipose Tissue and Metabolism
- Body Contouring and Surgery
- Lymphatic System and Diseases
- Burn Injury Management and Outcomes
- Tissue Engineering and Regenerative Medicine
- Wound Healing and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Injury Epidemiology and Prevention
- 3D Printing in Biomedical Research
- Homicide, Infanticide, and Child Abuse
- Periodontal Regeneration and Treatments
- Nanoparticle-Based Drug Delivery
- Organ Transplantation Techniques and Outcomes
- Myofascial pain diagnosis and treatment
- Enhanced Recovery After Surgery
- Adipokines, Inflammation, and Metabolic Diseases
- Dermatologic Treatments and Research
- Electrospun Nanofibers in Biomedical Applications
- Breast Implant and Reconstruction
- Bone fractures and treatments
- Xenotransplantation and immune response
- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical studies and practices
- Transplantation: Methods and Outcomes
Massachusetts General Hospital
2023-2024
Lahey Medical Center
2024
Lahey Hospital and Medical Center
2021-2024
Shriners Hospitals for Children - Boston
2023-2024
Harvard University
2023-2024
Tulane University
2014-2020
Louisiana State University
2020
University of New Orleans
2020
The field of reconstructive surgery faces significant challenges in addressing limb loss and disfigurement, with current organ preservation methods limited by short storage times. Decellularization offers a promising solution for generating engineered alternatives removing cellular material while preserving the extracellular matrix (ECM) providing scaffolds tissue regeneration. In this study, we developed robust protocol decellularizing whole digits from long-term freezer storage, achieving...
Adipose derived stromal/stem cells (ASCs) hold potential as cell therapeutics for a wide range of disease states; however, many expansion protocols rely on the use fetal bovine serum (FBS) culture nutrient supplement. The current study explores substitution lysates from expired human platelets (HPLs) an FBS substitute.Expired authorized blood center were lysed by freeze/thawing and used to examine ASCs with respect proliferation using hematocytometer counts, colony forming unit-fibroblast...
Obesity, defined as a body mass index of 30 kg/m2 or above, has increased considerably in incidence and frequency within the United States globally. Associated comorbidities including cardiovascular disease, type 2 diabetes mellitus, metabolic syndrome, nonalcoholic fatty liver disease have led to focus on mechanisms promoting prevention treatment obesity. Commonly utilized vitro models employ human mouse preadipocyte cell lines 2-dimensional (2D) format. Due structural, biochemical,...
Abstract Background Opioids are a mainstay of pain management. To limit the use opioids, enhanced recovery after surgery (ERAS) protocols implement multimodal approaches to treat postoperative pain. Objectives The aim this paper was be first assess efficacy an ERAS protocol for plastic outpatients that includes ultrasound-guided, surgeon-led regional blocks. Methods A retrospective review patients undergoing outpatient on performed. These were compared well-matched group not (pre-ERAS)....
Background Precise flap planning and perforator selection are paramount for successful surgery. Portable color-flow ultrasound (PCFU) is a convenient, low-cost, easily accessible imaging modality that pivotal in the of flaps where anatomic variability rule. Methods Perforator mapping was performed using an L12–4 linear-array probe connected to Android tablet. Images were obtained with Lumify app (Philips Lumify, usa.philips.com). characteristics recorded (arterial diameter, emergence points...
This study is the first to correlate sonographic findings of subcutaneous tissue structural and biomechanical properties.
Burn wound healing is a complex and long process. Despite extensive experience, plastic surgeons specialized teams in burn centers still face significant challenges. Among these challenges, the extent of burned soft tissue can evolve early phase, creating delicate balance between conservative treatments necrosing removal. Thermal burns are most common type, depth varies depending on multiple parameters, such as temperature exposure time. also time, secondary aggravation "shadow zone" remains...
Burn wound healing is a complex and long process. Despite extensive experience, plastic surgeons specialized teams in burn centers still face significant challenges. Among these challenges, the extent of burned soft tissue can evolve early phase, creating delicate balance between conservative treatments necrosing removal. Thermal burns are most common type, depth varies depending on multiple parameters, such as temperature exposure time. also time, secondary aggravation "shadow zone" remains...
Background The demand for body contouring surgery continues to rise. inclusion of the superficial fascial system (SFS) during closure such procedures has been shown improve outcomes; however, currently reported wound complication rates remain high. authors assess whether decreased quantities SFS are associated with complications in these patients. Methods A retrospective study patients undergoing was performed. Preoperatively, ultrasound images were obtained SFS. Using Cellprofiler, mean...
Pediatric burn patients that are victims of child abuse is a serious concern in our society today. Unfortunately, while existing literature describes the rates pediatric patients, no exists comparing stratified by genital burns. Our objective was to analyze regarding whether rate significantly different from unstratified patients. Terms “genital burns” with “child abuse” were searched through PubMed, Ovid, and Embase. 10 articles available 221 selected based on pertinence. Exclusion criteria...
PURPOSE: Wound dehiscence and extensive scarring continue to be the leading complications following body contouring procedures. Lack of structural support deep skin closure can result in hypertrophic scarring, recurrence laxity, wound dehiscence, thus decreasing patient satisfaction increasing reoperation rates. The superficial fascial system (SFS) has long been implicated as main source mechanical strength subcutaneous tissues. However, no studies date have shown this relationship....