Bohao Fang

ORCID: 0000-0001-5283-067X
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About
Contact & Profiles
Research Areas
  • Genetic diversity and population structure
  • Genetic and phenotypic traits in livestock
  • Genetic Mapping and Diversity in Plants and Animals
  • Fish Ecology and Management Studies
  • Evolution and Genetic Dynamics
  • Animal Behavior and Reproduction
  • Chromosomal and Genetic Variations
  • Amphibian and Reptile Biology
  • Genomics and Phylogenetic Studies
  • Metal Forming Simulation Techniques
  • Geotechnical Engineering and Soil Stabilization
  • Aquatic Invertebrate Ecology and Behavior
  • Identification and Quantification in Food
  • Bat Biology and Ecology Studies
  • Evolution and Paleontology Studies
  • Laser and Thermal Forming Techniques
  • Genomics and Chromatin Dynamics
  • Fungal and yeast genetics research
  • Plant and animal studies
  • Animal Vocal Communication and Behavior
  • Geotechnical Engineering and Underground Structures
  • Therapeutic Uses of Natural Elements
  • Innovations in Concrete and Construction Materials
  • Isotope Analysis in Ecology
  • Genetics, Bioinformatics, and Biomedical Research

Harvard University Press
2024-2025

Harvard University
2021-2024

East China University of Science and Technology
2024

Anhui Medical University
2024

University of Helsinki
2018-2022

Hunan University
2021

Jilin Jianzhu University
2020

Wuhan University
2016-2018

Knowledge on species’ breeding biology is the building blocks of avian life history theory. A review for current status knowledge at a global scale needed to highlight priority future research. We collected all available information three critical nesting parameters (clutch size, incubation period and nestling period) close 10 000 bird species in world identified taxonomic, geographic habitat gaps distribution biology. The results show that only one third extant are well known regarding...

10.1111/jav.00934 article EN Journal of Avian Biology 2016-09-02

Stickleback fishes in the family Gasterosteidae have become model organisms ecology and evolutionary biology. However, even case of most widely studied species this – three-spined stickleback (Gasterosteus aculeatus) worldwide phylogenetic relationships colonization history different populations lineages remain poorly resolved. Using a large collection samples covering parts distribution range, we subjected thousands single nucleotide polymorphisms to coalescent analyses order reconstruct...

10.1016/j.ympev.2018.06.008 article EN cc-by-nc-nd Molecular Phylogenetics and Evolution 2018-06-12

Abstract Population genetic theory predicts that small effective population sizes (Ne) and restricted gene flow limit the potential for local adaptation. In particular, probability of evolving similar phenotypes based on shared mechanisms (i.e., parallel evolution), is expected to be reduced. We tested these predictions in a comparative genomic study two ecologically geographically codistributed stickleback species (viz. Gasterosteus aculeatus Pungitius pungitius). found P. pungitius harbors...

10.1093/molbev/msab144 article EN Molecular Biology and Evolution 2021-05-05

Abstract Repeated and independent adaptation to specific environmental conditions from standing genetic variation is common. However, if limited, the evolution of similar locally adapted traits may be restricted genetically different potentially less optimal solutions or prevented happening altogether. Using a quantitative trait locus (QTL) mapping approach, we identified genomic regions responsible for repeated pelvic reduction (PR) in three crosses between nine‐spined stickleback...

10.1111/mec.15808 article EN cc-by Molecular Ecology 2021-01-19

Hybridization and convergent evolution are phenomena of broad interest in evolutionary biology, but their occurrence poses challenges for reconstructing affinities among affected taxa. Sticklebacks the genus Pungitius a case point: relationships taxonomic validity different species populations this circumpolarly distributed complex remain contentious due to traits regarded as diagnostic taxonomy, possibly also frequent hybridization To clarify globally, well study prevalence extent...

10.1111/mec.15204 article EN Molecular Ecology 2019-08-08

Abstract Recent comparative genomic studies have identified many human accelerated elements (HARs) with elevated substitution rates in the lineage. However, it remains unknown to what extent transcription factor binding sites (TFBSs) are under evolution humans and other primates. Here, we introduce two pooling-based phylogenetic methods dramatically enhanced sensitivity examine TFBSs. Using these new methods, show that more than 6000 TFBSs annotated genome experienced Hominini, apes, Old...

10.1038/s41467-023-36421-3 article EN cc-by Nature Communications 2023-02-11

10.1007/s00170-025-15082-0 article EN cc-by The International Journal of Advanced Manufacturing Technology 2025-02-03

Structural variants (SVs) are widespread in vertebrate genomes, yet their evolutionary dynamics remain poorly understood. Using 45 long-read de novo genome assemblies and pangenome tools, we analyze SVs within three closely related species of North American jays (Aphelocoma, scrub-jays) displaying a 60-fold range effective population size. We find rapid evolution architecture, including ~100 Mb variation size driven by dynamic satellite landscapes with unexpectedly long (> 10 kb) repeat...

10.1101/2025.02.11.637762 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2025-02-13

Incomplete lineage sorting (ILS) can lead to biased divergence time estimates. To explore if and how ILS has influenced the results of a recent worldwide phylogeny three-spined sticklebacks (Gasterosteus aculeatus), we estimated times among major clades by applying both concatenation approach multispecies coalescent (MSC) model single-nucleotide polymorphisms. further test influence different calibration strategies, applied calibrations root younger nodes in addition ones used previous...

10.1016/j.ympev.2019.106646 article EN cc-by Molecular Phylogenetics and Evolution 2019-10-18

Genomic structural variants (SVs) play a crucial role in adaptive evolution, yet their average fitness effects and characterization with pangenome tools are understudied wild animal populations. We constructed for House Finches ( Haemorhous mexicanus ), model studies of host-pathogen coevolution, using long-read sequence data on 16 individuals (32 de novo - assembled haplotypes) one outgroup. identified 887,118 SVs larger than 50 base pairs, mostly (60%) involving repetitive elements,...

10.1073/pnas.2409943121 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2024-11-12

Abstract Genomic structural variants (SVs) play a crucial role in adaptive evolution, yet their average fitness effects and characterization with pangenome tools are understudied wild animal populations. We constructed for House Finches, model studies of host-pathogen coevolution, using long-read sequence data on 16 individuals (32 de novo- assembled haplotypes) one outgroup. identified 643,207 SVs larger than 50 base pairs, mostly (60%) involving repetitive elements, reduced SV diversity...

10.1101/2024.05.15.594184 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-05-17

The high-altitude-adapted frog Rana kukunoris, occurring on the Tibetan plateau, is an excellent model to study life history evolution and adaptation harsh high-altitude environments. However, genomic resources for this species are still underdeveloped constraining attempts investigate underpinnings of adaptation.

10.1186/s12983-022-00482-9 article EN cc-by Frontiers in Zoology 2023-01-06

P. pastoris is a common host for effective biosynthesis of heterologous proteins as well small molecules. Accurate regulation gene transcription and protein synthesis necessary to coordinate synthetic circuits optimize cellular energy distribution. Traditional methanol or other inducible promoters, natural engineered, have defects in either fermentation safety expression capacity. The utilization chemical inducers typically adds complexity the product purification process, but there no...

10.1016/j.jare.2024.08.008 article EN cc-by-nc-nd Journal of Advanced Research 2024-08-01

Endemic to the Tibetan Plateau, Nanorana parkeri figures among highest altitude amphibians in world. The present work, which was conducted an alpine marsh at 4300 m altitude, is first report of species' reproductive ecology. breeding season, as indicated by presence amplectant pairs and fresh eggs ponds, lasted from early Mary July. ratios adult male female were 1.3 hibernation ponds 2.3 spawning ones. Males smaller than females. Amplexus typically axillary (81.7%), with a few exceptional...

10.1080/00222933.2016.1205155 article EN Journal of Natural History 2016-07-11

Abstract Population genetic theory predicts that small effective population sizes ( N e ) and restricted gene flow limit the potential for local adaptation. In particular, probability of evolving similar phenotypes based on shared mechanisms (i.e. parallel evolution), is expected to be reduced. We tested these predictions in a comparative genomic study two ecologically geographically co-distributed stickleback species (viz. Gasterosteus aculeatus Pungitius pungitius ). found P. harbours less...

10.1101/2021.01.26.428263 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-01-26

Abstract An important model system for the study of genomic mechanisms underlying parallel ecological adaptation in wild is three-spined stickleback ( Gasterosteus aculeatus ), which has repeatedly colonized and adapted to freshwater from sea throughout northern hemisphere. Previous studies have identified numerous regions showing consistent genetic differentiation between marine ecotypes, but these are typically based on limited geographic sampling biased towards Eastern Pacific. We...

10.1101/826412 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2019-10-31

Abstract Repeated and independent adaptation to specific environmental conditions from standing genetic variation is common. However, if limited, the evolution of similar locally adapted traits may be restricted genetically different potentially less optimal solutions or prevented happening altogether. Using a quantitative trait locus (QTL) mapping approach, we identified genomic regions responsible for repeated pelvic reduction (PR) in three crosses between nine-spined stickleback...

10.1101/2020.01.17.908970 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-01-17

Abstract Life-history theory predicts that organisms inhabiting harsh environments such as high altitudes should invest less in reproduction and more survival. Testis size is associated with the intensity of male-male competition for mating thus may be treated an indicator male reproductive investment. Hence, it expected will reduce their testis increasingly environments. Here we test this prediction a toad species, Scutiger boulengeri , endemic to Tibetan plateau using data from three...

10.1163/15707563-17000016 article EN Animal Biology 2018-01-01

Partial separation of a peripheral population may lead to its divergence and, potentially, speciation due genetic drift followed by selection and geographic isolation. This process cause taxonomic uncertainty because reproductive isolation in allopatry cannot be verified directly. The two Nearctic allopatric species magpies (Aves, Corvidae:

10.1093/cz/zoad048 article EN cc-by-nc Current Zoology 2023-11-01

Qian, Y.; Fang, B.; Jin, Y., and Wang, R., 2020. Experimental study on effect of disc spacing soil failure state expanded pile under the action horizontal force application in oceanographic engineering. In: Yang, D.F. H. (eds.), Recent Advances Marine Geology Environmental Oceanography. Journal Coastal Research, Special Issue No. 108, pp. 283–287. Coconut Creek (Florida), ISSN 0749-0208.In engineering, concrete piles represent a new type foundation. This article observes small-scale...

10.2112/jcr-si108-057.1 article EN Journal of Coastal Research 2020-09-28

10.5281/zenodo.4722879 article Zenodo (CERN European Organization for Nuclear Research) 2021-05-05

The European whitefish (Coregonus lavaretus) species complex is a classic example of recent adaptive radiation. Here, we examine population introduced to northern Finnish Lake Tsahkal in the late 1960s, where three divergent morphs (viz. littoral, pelagic, and profundal feeders) were found 10 generations after. Using demographic modeling based on genomic data, show that evolved during phase strict isolation, refuting rapid sympatric divergence scenario. lake now an artificial hybrid zone...

10.1111/evo.14559 article EN cc-by-nc Evolution 2022-07-07
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