- Heavy Metal Exposure and Toxicity
- Effects and risks of endocrine disrupting chemicals
- Trace Elements in Health
- Heavy metals in environment
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Birth, Development, and Health
- Genetics and Neurodevelopmental Disorders
- Aluminum toxicity and tolerance in plants and animals
- Pregnancy and Medication Impact
- Air Quality and Health Impacts
- Diet and metabolism studies
- Pregnancy and preeclampsia studies
- Dental Research and COVID-19
- Tryptophan and brain disorders
- Liver Disease Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases
- Selenium in Biological Systems
- Dental Radiography and Imaging
- Gestational Diabetes Research and Management
- Pharmacological Effects and Toxicity Studies
- Antibiotic Use and Resistance
- Health, Environment, Cognitive Aging
- Child Nutrition and Water Access
- Plant Molecular Biology Research
Anhui Medical University
2016-2025
Linyi People's Hospital
2025
Harbin Institute of Technology
2025
Hangzhou Medical College
2025
Zhejiang Provincial People's Hospital
2025
Ministry of Education of the People's Republic of China
2021-2024
Sun Yat-sen University
2024
Heilongjiang Electric Power Workers University
2024
Northeast Agricultural University
2023
Ministry of Agriculture and Rural Affairs
2023
Objective Previous study have shown that lipid accumulation product (LAP), visceral adiposity index (VAI), triglyceride/high-density lipoprotein cholesterol ratio (TG/HDL-C) and triglycerides/glucose (TyG index) could be simple clinical indicators of insulin resistance (IR) based on anthropometric and/or biochemical parameters. However, the rational preferred surrogate marker IR in different population has yet to validated. The aim this was evaluating practicability LAP, VAI, TG/HDL-C, TyG...
Previous studies have found associations between single toxic metals, such as arsenic and cadmium, kidney function in adults with diabetes. However, regards to other metals metal mixtures are still limited.Our study aimed investigate the urinary concentrations of 5 selected using a sample older diabetes mellitus Chinese communities.In (n = 5186), 592 eligible subjects were included this study. Urinary i.e., (As), cadmium (Cd), vanadium (V), cobalt (Co), thallium (Tl), measured by inductively...
The evidence about the effect of essential trace element (ETE) mixture on cognitive function amongst older adults is limited. This study aims to evaluate associations single ETEs and ETE with using a representative sample community-dwelling in China.A total 3814 were included study. Urinary concentrations selenium (Se), vanadium (V), cobalt (Co), strontium (Sr), molybdenum (Mo) detected by inductively coupled plasma mass spectrometry. Cognitive was assessed Chinese version Mini-Mental State...
Attenuated insulin-sensitivity (IS) is a characteristic of type 2 diabetes (T2D) and closely linked to non-alcoholic fatty liver disease (NAFLD). In recent years, many surrogate markers IS have emerged predict NAFLD. A natural log transformation the glucose disposal rate (loge GDR) has been proposed as new model for in patients with T2D. Our aim explore correlation between loge GDR NAFLD normoalbuminuric total 1227 T2D were involved our study. was evaluated by ultrasound. Biochemical...
Aims Non-alcoholic fatty liver disease (NAFLD) is closely related to type 2 diabetes (T2D), with reduced insulin sensitivity being a key factor in their disrupted metabolic processes. The single point estimator (SPISE) novel index. This study aims explore the association between SPISE and NAFLD T2D population. Methods included total of 2,459 patients T2D. was calculated based on high density lipoprotein-cholesterol (HDL-c), triglycerides (TG), body mass index (BMI). Participants were...
Spontaneous clearance of hepatitis B virus (HBV) is frequent in adults (95%) but rare infants (5%), emphasizing the critical role age-related hepatic immunocompetence. However, underlying mechanisms hepatocyte-specific immunosurveillance and age-dependent HBV remain unclear. Here, we identified PGLYRP2 as a pattern recognition receptor with expression, demonstrated that phase separation was driver spontaneous hepatocytes. Mechanistically, recognized potentially eliminated covalently closed...
ABSTRACT Carbapenem-resistant Morganella morganii (CRMM) isolates, particularly those producing Klebsiella pneumoniae carbapenemase-2 (KPC-2) or New Delhi metallo-β-lactamase-1 (NDM-1), are increasingly being recognized as causative agents of nosocomial infections. However, systematic phylogeography and genetic characterization these isolates worldwide still lacking. Here, through seven years surveillance CRMM in a tertiary hospital, we analyzed the genomic characteristics bla KPC-2 - NDM-1...
The combined effects of physical activity (PA) and nitrogen dioxide (NO2) on fasting plasma glucose (FPG) levels have rarely been studied. This study aimed to examine whether long-term exposure NO2 attenuates the association between PA FPG in non-diabetic older adults. A total 2600 elderly Chinese adults were included this cross-sectional study. data collected using International Physical Activity Questionnaire (IPAQ). Space-Time Extra-Trees model was utilized estimate annual concentration...
The relationship between prenatal arsenic exposure at low levels and poor development in children, especially regard to neurodevelopment, has aroused several concerns, but the conclusions have been inconsistent. It still remains unclear whether such adverse effect is associated with a specific profile of developing brain early life. To investigate association utero children’s behaviour, we performed large prospective birth cohort study including 2315 mother-infant pairs Anhui Province,...